Search Results - "Rakba, Nafissa"

Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C by Guyader, Dominique, Thirouard, Anne-Sophie, Erdtmann, Lars, Rakba, Nafissa, Jacquelinet, Sylvie, Danielou, Hélène, Perrin, Michèle, Jouanolle, Anne-Marie, Brissot, Pierre, Deugnier, Yves

“…Background/Aims Patients with chronic hepatitis C have frequently mild to moderate liver iron overload which increases with fibrosis stage. Thus, it has been…”
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Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines by Rakba, Nafissa, Loyer, Pasca, Gilot, David, Delcros, Jean Guy, Glaise, Denise, Baret, Paul, Pierre, Jean Louis, Brissot, Pierre, Lescoat, Gérard

“…We investigated the effects of a new iron chelator, O-Trensox (TRX), compared with desferrioxamine (DFO), on proliferation and apoptosis in cultures of the…”
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Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study by Gaboriau, François, Chantrel-Groussard, Karine, Rakba, Nafissa, Loyer, Pascal, Pasdeloup, Nicole, Hider, Robert C., Brissot, Pierre, Lescoat, Gérard

“…The present study analyzes the iron mobilization, the cytoprotective, and the antiproliferative effects of the lipophilic hydroxypyridinone CP411, in…”
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Bgugaine, a pyrrolidine alkaloid from Arisarum vulgare, is a strong hepatotoxin in rat and human liver cell cultures by Rakba, Nafissa, Melhaoui, Ahmed, Loyer, Pascal, Guy Delcros, Jean, Morel, Isabelle, Lescoat, Gérard

“…Toxicity of bgugaine, a pyrrolidine alkaloid extracted from the tubers of Arisarum vulgare, was studied in three different liver cell culture models: (1) the…”
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New 8-hydroxyquinoline and catecholate iron chelators: influence of their partition coefficient on their biological activity11Abbreviations: Kpart, partition coeffient; DFO, desferrioxamine B; TRX, O-Trensox; pFe = −log[Fe3+aq] at pH 7.4 with [Ligand] = 10 μM and [Fe] = 1 μM; LDH, lactate dehydrogenase; and PBS, phosphate-buffered saline by Henry, Christophe, Rakba, Nafissa, Imbert, Daniel, Thomas, Fabrice, Baret, Paul, Serratrice, Guy, Gaude, Didier, Pierre, Jean-Louis, Ward, Roberta J., Crichton, Robert R., Lescoat, Gerard

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New 8-hydroxyquinoline and catecholate iron chelators: influence of their partition coefficient on their biological activity by Henry, Christophe, Rakba, Nafissa, Imbert, Daniel, Thomas, Fabrice, Baret, Paul, Serratrice, Guy, Gaude, Didier, Pierre, Jean-Louis, Ward, Roberta J., Crichton, Robert R., Lescoat, Gerard

“…Four new hexadendate chelators, three hydroxyquinoline-based, Csox, O-Trensox, Cox750, and one catecholate-based CacCam—which have comparable skeletal…”
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Iron Mobilisation and Cellular Protection by a New Synthetic Chelator O-Trensox by Rakba, Nafissa, Aouad, Fouad, Henry, Christophe, Caris, Catherine, Morel, Isabelle, Baret, Paul, Pierre, Jean-Louis, Brissot, Pierre, Ward, Roberta J, Lescoat, Gérard, Crichton, Robert R

“…We tested a new synthetic, 8-hydroxyquinoline-based, hexadentate iron chelator, O-Trensox and compared it with desferrioxamine B (DFO). Iron mobilisation was…”
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580 Iron and chronic hepatitis C: clinical, biological, histological correlations and impaact on fibrosis progression by Guyader, Dominique, Rakba, Nafissa, Thirouard, Anne-Sophie, Jacquelinet, Sylvie, Danielou, Hélène, Perrin, Michèle, Jouanolle, Anne-Marie, Brissot, Pierre, David, Véronique, Deugnier, Yves

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