Search Results - "Raju, S. Vamsee"

Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia by Lin, Vivian Y, Fain, Matthew D, Jackson, Patricia L, Berryhill, Taylor F, Wilson, Landon S, Mazur, Marina, Barnes, Stephen J, Blalock, J Edwin, Raju, S Vamsee, Rowe, Steven M

“…Cigarette smoking is associated with chronic obstructive pulmonary disease and chronic bronchitis. Acquired ion transport abnormalities, including cystic…”
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A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-β-Mediated CFTR Expression by Dutta, Rajib K., Chinnapaiyan, Srinivasan, Rasmussen, Lawrence, Raju, S. Vamsee, Unwalla, Hoshang J.

“…Transforming growth factor β (TGF-β), signaling induced by cigarette smoke (CS), plays an important role in the progression of airway diseases, like chronic…”
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Cigarette smoke and CFTR: implications in the pathogenesis of COPD by Rab, Andras, Rowe, Steven M, Raju, S Vamsee, Bebok, Zsuzsa, Matalon, Sadis, Collawn, James F

“…Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder consisting of chronic bronchitis and/or emphysema. COPD patients suffer from…”
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Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in the Lower Airways in COPD by Dransfield, Mark T., MD, Wilhelm, Andrew M., MD, Flanagan, Brian, MD, Courville, Clifford, MD, Tidwell, Sherry L., RRT, Raju, S. Vamsee, PhD, Gaggar, Amit, MD, PhD, Steele, Chad, PhD, Tang, Li Ping, DVM, Liu, Bo, MD, Rowe, Steven M., MD, MSPH

“…Background Cigarette smoke and smoking-induced inflammation decrease cystic fibrosis transmembrane conductance regulator (CFTR) activity and mucociliary…”
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A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease by Sloane, Peter A, Shastry, Suresh, Wilhelm, Andrew, Courville, Clifford, Tang, Li Ping, Backer, Kyle, Levin, Elina, Raju, S Vamsee, Li, Yao, Mazur, Marina, Byan-Parker, Suzanne, Grizzle, William, Sorscher, Eric J, Dransfield, Mark T, Rowe, Steven M

“…Mucus stasis in chronic obstructive pulmonary disease (COPD) is a significant contributor to morbidity and mortality. Potentiators of cystic fibrosis…”
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Cigarette Smoke Induces Systemic Defects in Cystic Fibrosis Transmembrane Conductance Regulator Function by VAMSEE RAJU, S, JACKSON, Patricia L, JONES, Caleb W, BOYDSTON, Jeremy A, CLANCY, J. P, BOWEN, Larry E, ACCURSO, Frank J, BLALOCK, J. Edwin, DRANSFIELD, Mark T, ROWE, Steven M, COURVILLE, Clifford A, McNICHOLAS, Carmel M, SLOANE, Peter A, SABBATINI, Gina, TIDWELL, Sherry, LI PING TANG, BO LIU, FORTENBERRY, James A

“…Several extrapulmonary disorders have been linked to cigarette smoking. Smoking is reported to cause cystic fibrosis transmembrane conductance regulator (CFTR)…”
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HIV Increases the Risk of Cigarette Smoke-Induced Emphysema Through MMP-9 by Staitieh, Bashar S., Malik, Simran, Auld, Sara C., Wigger, Gregory W., Fan, Xian, Roth, Andrew T., Chatterjee, Tanima, Arora, Itika, Raju, S. Vamsee, Heath, Sonya, Aggrawal, Saurabh

“…HIV is associated with an increased risk for emphysema. Matrix metalloproteinase 9 (MMP-9) is a lung tissue remodeling enzyme associated with emphysema. We…”
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Roflumilast reverses CFTR-mediated ion transport dysfunction in cigarette smoke-exposed mice by Raju, S Vamsee, Rasmussen, Lawrence, Sloane, Peter A, Tang, Li Ping, Libby, Emily Falk, Rowe, Steven M

“…Dysfunction in cystic fibrosis transmembrane conductance regulator (CFTR) can be elicited by cigarette smoke and is observed in patients with chronic…”
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The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke by Raju, S Vamsee, Lin, Vivian Y, Liu, Limbo, McNicholas, Carmel M, Karki, Suman, Sloane, Peter A, Tang, Liping, Jackson, Patricia L, Wang, Wei, Wilson, Landon, Macon, Kevin J, Mazur, Marina, Kappes, John C, DeLucas, Lawrence J, Barnes, Stephen, Kirk, Kevin, Tearney, Guillermo J, Rowe, Steven M

“…Acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction may contribute to chronic obstructive pulmonary disease pathogenesis and is a…”
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Evaluation of secondhand smoke effects on CFTR function in vivo by Rasmussen, Lawrence W, Stanford, Denise, Patel, Krina, Raju, S Vamsee

“…[...]of reduced CFTR-mediated ion transport, CF airways fail to maintain optimal surface hydration and clear inhaled pathogens. Exposure to SHS is a risk…”
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Comparative transcriptomics in human COPD reveals dysregulated genes uniquely expressed in ferrets by Hussain, Shah S, Edwards, Yvonne J K, Libby, Emily Falk, Stanford, Denise, Byzek, Stephen A, Sin, Don D, McDonald, Merry-Lynn, Raju, S Vamsee, Rowe, Steven M

“…Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with poor treatment options. However, most mouse models of COPD produce a primarily…”
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Maternal Smoking Induces Acquired CFTR Dysfunction in Neonatal Rats by McCormick, Lydia L, Phillips, Scott E, Kaza, Niroop, Tang, Li Ping, Rasmussen, Lawrence, Byzek, Stephen A, Raju, S Vamsee, Rowe, Steven Mark

“…Cystic fibrosis, an autosomal-recessive genetic disorder, is a consequence of dysfunctional CFTR function and results in defective respiratory host defense,…”
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Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis and Other Diseases of Mucus Clearance by Raju, S. Vamsee, BPharm, PhD, Solomon, George M., MD, Dransfield, Mark T., MD, Rowe, Steven M., MD, MSPH

“…Chronic obstructive pulmonary disease (COPD) is a major public health problem. No therapies alter the natural history of the disease. Chronic bronchitis is…”
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Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis by Lambert, James A, Raju, S Vamsee, Tang, Li Ping, McNicholas, Carmel M, Li, Yao, Courville, Clifford A, Farris, Roopan F, Coricor, George E, Smoot, Lisa H, Mazur, Marina M, Dransfield, Mark T, Bolger, Graeme B, Rowe, Steven M

“…Cigarette smoking causes acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction and is associated with delayed mucociliary clearance…”
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Recovery of Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction after Smoking Cessation by Courville, Clifford A, Raju, S Vamsee, Liu, Bo, Accurso, Frank J, Dransfield, Mark T, Rowe, Steven M

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Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction and Radiographic Bronchiectasis in Current and Former Smokers: A Cross-Sectional Study by Teerapuncharoen, Krittika, Wells, J Michael, Raju, S Vamsee, Raraigh, Karen S, Atalar Aksit, Melis, Cutting, Garry R, Rasmussen, Lawrence, Nath, P Hrudaya, Bhatt, Surya P, Solomon, George M, Dransfield, Mark T, Rowe, Steven M

“…Recently published data indicated that cigarette smoking causes acquired CFTR dysfunction, manifested by increased sweat chloride (2), altered sweat rate (3),…”
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Haemophilus influenzae persists in biofilm communities in a smoke-exposed ferret model of COPD by Hunt, Benjamin C, Stanford, Denise, Xu, Xin, Li, Jindong, Gaggar, Amit, Rowe, Steven M, Raju, S Vamsee, Swords, W Edward

“…Non-typeable (NTHi) is a common inhabitant of the human nasopharynx and upper airways that can cause opportunistic infections of the airway mucosa including…”
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Use of ferrets for electrophysiologic monitoring of ion transport by Kaza, Niroop, Raju, S Vamsee, Cadillac, Joan M, Trombley, John A, Rasmussen, Lawrence, Tang, Liping, Dohm, Erik, Harrod, Kevin S, Rowe, Steven M

“…Limited success achieved in translating basic science discoveries into clinical applications for chronic airway diseases is attributed to differences in…”
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Validation of gene editing efficiency with CRISPR-Cas9 system directly in rat zygotes using electroporation mediated delivery and embryo culture by Challa, Anil K., Stanford, Denise, Allen, Antonio, Rasmussen, Lawrence, Amanor, Ferdinand K., Raju, S. Vamsee

“…Successful use of the CRISPR-Cas9 system for gene manipulation relies on identifying effective and efficient guide RNA sequences (gRNAs). When the goal is to…”
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Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting by Kuprys, Paulius V., Tsukamoto, Hidekazu, Gao, Bin, Jia, Lin, McGowan, Jacob, Coopersmith, Craig M., Moreno, Maria Camargo, Hulsebus, Holly, Meena, Avtar S., Souza-Smith, Flavia M., Roper, Philip, Foster, Michelle T., Raju, S. Vamsee, Marshall, S. Alex, Fujita, Mayumi, Curtis, Brenda J., Wyatt, Todd A., Mandrekar, Pranoti, Kovacs, Elizabeth J., Choudhry, Mashkoor A.

“…On January 26, 2018, the 23rd annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the University of Colorado Denver, Anschutz…”
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