Search Results - "Raju, Diana"

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease by Schonauer, Sophie, Körschen, Heinz G., Penno, Anke, Rennhack, Andreas, Breiden, Bernadette, Sandhoff, Konrad, Gutbrod, Katharina, Dörmann, Peter, Raju, Diana N., Haberkant, Per, Gerl, Mathias J., Brügger, Britta, Zigdon, Hila, Vardi, Ayelet, Futerman, Anthony H., Thiele, Christoph, Wachten, Dagmar

“…The lysosomal acid β-glucosidase GBA1 and the non-lysosomal β-glucosidase GBA2 degrade glucosylceramide (GlcCer) to glucose and ceramide in different cellular…”
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Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics by Raju, Diana, Schonauer, Sophie, Hamzeh, Hussein, Flynn, Kevin C, Bradke, Frank, Vom Dorp, Katharina, Dörmann, Peter, Yildiz, Yildiz, Trötschel, Christian, Poetsch, Ansgar, Breiden, Bernadette, Sandhoff, Konrad, Körschen, Heinz G, Wachten, Dagmar

“…Glycosphingolipids are key elements of cellular membranes, thereby, controlling a variety of cellular functions. Accumulation of the simple glycosphingolipid…”
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Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains by Raju, Diana N, Hansen, Jan N, Rassmann, Sebastian, Stüven, Birthe, Jikeli, Jan F, Strünker, Timo, Körschen, Heinz G, Möglich, Andreas, Wachten, Dagmar

“…Inside the female genital tract, mammalian sperm undergo a maturation process called capacitation, which primes the sperm to navigate across the oviduct and…”
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The Non-lysosomal β-Glucosidase GBA2 Is a Non-integral Membrane-associated Protein at the Endoplasmic Reticulum (ER) and Golgi by Körschen, Heinz G., Yildiz, Yildiz, Raju, Diana Nancy, Schonauer, Sophie, Bönigk, Wolfgang, Jansen, Vera, Kremmer, Elisabeth, Kaupp, U. Benjamin, Wachten, Dagmar

“…GBA1 and GBA2 are both β-glucosidases, which cleave glucosylceramide (GlcCer) to glucose and ceramide. GlcCer is a main precursor for higher order…”
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Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics: e1005063 by Raju, Diana, Schonauer, Sophie, Hamzeh, Hussein, Flynn, Kevin C, Bradke, Frank, Dorp, Katharina vom, Dörmann, Peter, Yildiz, Yildiz, Trötschel, Christian, Poetsch, Ansgar, Breiden, Bernadette, Sandhoff, Konrad, Körschen, Heinz G, Wachten, Dagmar

“…Glycosphingolipids are key elements of cellular membranes, thereby, controlling a variety of cellular functions. Accumulation of the simple glycosphingolipid…”
Get full text