Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases

Neurodegeneration and neurodegenerative disorders have been a global health issue affecting the aging population worldwide. Recent advances in stem cell biology have changed the current face of neurodegenerative disease modeling, diagnosis, and transplantation therapeutics. Stem cells also serve the...

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Bibliographic Details
Published in:	Frontiers in molecular biosciences Vol. 3; p. 72
Main Authors:	Singh, Shripriya, Srivastava, Akriti, Srivastava, Pranay, Dhuriya, Yogesh K, Pandey, Ankita, Kumar, Dipak, Rajpurohit, Chetan S
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 08-11-2016
Subjects:	diagnosis disease modeling Induced pleuripotent stem cells (iPSCs) Molecular Biosciences Neurodegenerative disorders Stem Cells stem cells diagnosis neurodegenerative disorders disease modeling Induced pluripotent stem cells (iPSCs)
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Summary:	Neurodegeneration and neurodegenerative disorders have been a global health issue affecting the aging population worldwide. Recent advances in stem cell biology have changed the current face of neurodegenerative disease modeling, diagnosis, and transplantation therapeutics. Stem cells also serve the purpose of a simple tool for screening therapeutic drugs and chemicals. We present the application of stem cells and induced pluripotent stem cells (iPSCs) in the field of neurodegeneration and address the issues of diagnosis, modeling, and therapeutic transplantation strategies for the most prevalent neurodegenerative disorders. We have discussed the progress made in the last decade and have largely focused on the various applications of stem cells in the neurodegenerative research arena.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 Reviewed by: Vimal Kishor Singh, Delhi Technological University, India; Abhijit Biswas, University of Notre Dame, USA Edited by: Megha Agrawal, University of Illinois at Chicago, USA This article was submitted to Molecular Diagnostics, a section of the journal Frontiers in Molecular Biosciences
ISSN:	2296-889X 2296-889X
DOI:	10.3389/fmolb.2016.00072