Search Results - "Rajoria, Shilpi"

Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants by Shanmugam, Arulkumaran, Rajoria, Shilpi, George, Andrea L, Mittelman, Abraham, Suriano, Robert, Tiwari, Raj K

“…Adjuvants serve as catalysts of the innate immune response by initiating a localized site of inflammation that is mitigated by the interactions between…”
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Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors by Khoo, Ting Chean, Tubbesing, Kate, Rudkouskaya, Alena, Rajoria, Shilpi, Sharikova, Anna, Barroso, Margarida, Khmaladze, Alexander

“…Transferrin (Tf) is an essential serum protein which delivers iron throughout the body via transferrin-receptor (TfR)-mediated uptake and iron release in early…”
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Endothelial progenitor cell biology in disease and tissue regeneration by George, Andrea L, Bangalore-Prakash, Pradeep, Rajoria, Shilpi, Suriano, Robert, Shanmugam, Arulkumaran, Mittelman, Abraham, Tiwari, Raj K

“…Endothelial progenitor cells are increasingly being studied in various diseases ranging from ischemia, diabetic retinopathy, and in cancer. The discovery that…”
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Hypoxia and estrogen are functionally equivalent in breast cancer-endothelial cell interdependence by George, Andrea L, Rajoria, Shilpi, Suriano, Robert, Mittleman, Abraham, Tiwari, Raj K

“…Rapid breast tumor development relies on formation of new vasculature to supply the growing malignancy with oxygenated blood. Previously we found that estrogen…”
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Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer by Rajoria, Shilpi, Suriano, Robert, George, Andrea, Shanmugam, Arulkumaran, Schantz, Stimson P, Geliebter, Jan, Tiwari, Raj K

“…Thyroid cancer is the most common endocrine related cancer with increasing incidences during the past five years. Current treatments for thyroid cancer, such…”
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Molecular target based combinational therapeutic approaches in thyroid cancer by Rajoria, Shilpi, Suriano, Robert, George, Andrea L, Kamat, Ameet, Schantz, Stimson P, Geliebter, Jan, Tiwari, Raj K

“…Thyroid cancer, as with other types of cancer, is dependent on angiogenesis for its continued growth and development. Interestingly, estrogen has been shown to…”
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Ex vivo derived primary melanoma cells: implications for immunotherapeutic vaccines by Suriano, Robert, Rajoria, Shilpi, L George, Andrea, Geliebter, Jan, Wallack, Marc, Tiwari, Raj K

“…Transformation of the pigment producing melanocytes into melanoma is a complex multi-step process involving the enhanced expression of various antigens…”
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Metastatic phenotype is regulated by estrogen in thyroid cells by Rajoria, Shilpi, Suriano, Robert, Shanmugam, Arulkumaran, Wilson, Yushan Lisa, Schantz, Stimson P, Geliebter, Jan, Tiwari, Raj K

“…Over 200 million people worldwide are affected by thyroid proliferative diseases, including cancer, adenoma, and goiter, annually. The incidences of thyroid…”
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Spatial light modulator based active wide-field illumination for ex vivo and in vivo quantitative NIR FRET imaging by Zhao, Lingling, Abe, Ken, Rajoria, Shilpi, Pian, Qi, Barroso, Margarida, Intes, Xavier

“…Fluorescence lifetime imaging is playing an increasing role in drug development by providing a sensitive method to monitor drug delivery and receptor-ligand…”
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In vivo receptor mediated near‐infrared transferrin uptake using fluorescence lifetime fret: implications in the targeted drug delivery (58.9) by Rajoria, Shilpi, Zhao, Lingling, Intes, Xavier, Barroso, Margarida

“…Traditional cancer therapy generally leads to harmful side effects, thus warranting development of targeted therapies which are better tolerated by cancer…”
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Imaging Tumor Targeted Delivery using FRET in vivo by Rudkouskaya, Alena, Anderson, Kate, Rajoria, Shilpi, Zhao, Lingling, Sinsuebphon, Nattawut, Intes, Xavier, Barroso, Margarida

“…Abstract only Our goal is to develop <em style=”mso‐bidi‐font‐style: normal;”>in vivo non‐invasive optical imaging assays for optimization of anti‐cancer drug…”
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Abstract 1432: CXCL8 is a secretory inflammatory stimulus of the activated TME that modulates breast cancer phenotype by George, Andrea L., Bednarczyk, Robert, Rajoria, Shilpi, Hanly, Elyse, Suriano, Robert, Mittelman, Abraham, Tiwari, Raj K.

“…Abstract The tumor microenvironment (TME) is a heterogeneous niche consisting of numerous stromal cells, structural components, and secreted molecules from…”
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Abstract 2829: Patient-derived primary melanoma cells that differentially express melano-specific antigens as a model for vaccines by Suriano, Robert, George, Andrea L., Rajoria, Shilpi, Geliebter, Jan, Tiwari, Raj K., Wallack, Marc

“…Abstract Transformation of pigment producing melanocytes into melanoma is a complex multi-step process involving the generation and/or over expression of…”
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Abstract 4558: Synergistic effect of alcohol and estradiol in breast cancer by Singh, Ajeet, Shanmugam, Arulkumaran, Rajoria, Shilpi, George, Andrea, Suriano, Robert

“…Abstract Breast cancer is the most common malignancy and the second leading cause of death among women in the United States. In addition to the various risks…”
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The Role of Macrophage-Induced Inflammation in Thyroid Cancer Progression by Saman, Masoud, Rajoria, Shilpi, Tuli, Neha, Hanley, Elyse, Shin, Edward J., Tiwari, Raj

“…Objectives: Tumor microenvironment, specifically inflammation-mediated molecular changes, define tumor phenotype. Papillary thyroid cancer (PTC) is the…”
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Abstract 96: Estrogen modulates cellular and molecular markers of hypoxic tumor microenvironment in thyroid cancer by Rajoria, Shilpi, Hanly, Elyse, George, Andrea, Suriano, Robert, Geliebter, Jan, Saman, Masoud, Schantz, Stimson, Tiwari, Raj K.

“…Abstract Thyroid proliferative diseases are three to four times more prevalent in women than in men. Our laboratory has systemically elucidated the role of…”
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Abstract 1048: Targeted BRAF therapy attenuates the promotional activity of estrogen in thyroid cancer by Hanly, Elyse K., Rajoria, Shilpi, George, Andrea L., Suriano, Robert, Geliebter, Jan, Pantelides, Harry, Shin, Edward J., Tiwari, Raj K.

“…Abstract Thyroid cancer, which is three to four times more prevalent in women than men, is the most common endocrine-related cancer in the United States and…”
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Abstract 304: Proinflammatory secretory chemokine CXCL8 regulates intercellular cross-talk in the breast cancer tumor microenvironment by Jussim, Casey, George, Andrea L., Rajoria, Shilpi, Suriano, Robert, Shanmugam, Arulkumaran, Mittelman, Abraham, Tiwari, Raj K.

“…Abstract The cellular composition of the tumor microenvironment (TME) and soluble effector molecules mediating intercellular cross-talk are important…”
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Abstract 1494: Intrinsic and extrinsic TME factors modulate breast cancer progression by George, Andrea L., Rajoria, Shilpi, Suriano, Robert, Mittelman, Abraham, Tiwari, Raj K.

“…Abstract The tumor microenvironment (TME) of breast cancer is a heterogeneous population of tumor cells, infiltrating endothelial cells, immunomodulatory…”
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Abstract 1520: Estrogen modulates angiogenic factors of thyroid tumor microenvironment by Rajoria, Shilpi, George, Andrea, Suriano, Robert, Shin, Edward J., Geliebter, Jan, Tiwari, Raj K.

“…Abstract Thyroid cancer is the most common endocrine related cancer with the incidences occurring three to four times higher in women than in men, thus…”
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