Search Results - "Rajmonova, Anezka"
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Vertical targeting of the PI3K/AKT pathway at multiple points is synergistic and effective for non-Hodgkin lymphoma
Published in Experimental hematology & oncology (01-11-2024)“…The phosphatidylinositol 3‑kinase/protein kinase B (PI3K/AKT) signaling pathway is critically active in many cell types, both normal and neoplastic. Many…”
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Journal Article -
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Impact of PIK3CA gain and PTEN loss on mantle cell lymphoma biology and sensitivity to targeted therapies
Published in Blood advances (22-10-2024)“…•PIK3CA gain and PTEN loss decrease the dependence of MCL cells on BCR signaling and antiapoptotic BCL2.•PIK3CA gain and PTEN loss lead to complex metabolic…”
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Journal Article