Search Results - "Rajki, Anikó"
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P2 Calcium Induced Intramitochondrial cAMP Signalling Enhances Aldosterone Secretion
Published in Artery research (01-12-2019)“…Elevation of plasma [K + ] and [angiotensin II] (Ang II), two major physiological stimuli of adrenal zona glomerulosa cells, increase aldosterone production by…”
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2
Mitochondrial cAMP exerts positive feedback on mitochondrial Ca2+ uptake via the recruitment of Epac1
Published in Journal of cell science (15-05-2018)“…We have previously demonstrated in H295R adrenocortical cells that the Ca2+-dependent production of mitochondrial cAMP (mt-cAMP) by the matrix soluble adenylyl…”
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3
Calcium-dependent mitochondrial cAMP production enhances aldosterone secretion
Published in Molecular and cellular endocrinology (05-09-2015)“…•HCO3− activates mitochondrial adenylyl cyclase (sAC) in human adrenocortical cells.•Angiotensin II causes a mitochondrial [cAMP] rise in a…”
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4
Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB 1 ) Receptor
Published in Frontiers in endocrinology (Lausanne) (20-10-2021)“…The G protein-coupled type 1 cannabinoid receptor (CB R) mediates virtually all classic cannabinoid effects, and both its agonists and antagonists hold major…”
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5
Molecular and functional characterization of Hv1 proton channel in human granulocytes
Published in PloS one (23-11-2010)“…Voltage-gated proton current (I(Hv)) has been characterized in several cell types, but the majority of the data was collected in phagocytes, especially in…”
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6
Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3
Published in iScience (21-07-2023)“…Molecular interactions between anorexigenic leptin and orexigenic endocannabinoids, although of great metabolic significance, are not well understood…”
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7
Mitochondrial Ca2+ uptake correlates with the severity of the symptoms in autosomal dominant optic atrophy
Published in Cell calcium (Edinburgh) (01-01-2015)“…Graphical abstract…”
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8
Control mechanisms of mitochondrial Ca2+ uptake – feed-forward modulation of aldosterone secretion
Published in Molecular and cellular endocrinology (28-04-2012)“…► Regulation of mitochondrial Ca2+ uptake is elusive. ► We review the role of p38MAPK/nPKC isoforms and Mg2+ in the control of Ca2+ uptake. ► We study the…”
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9
Mitochondrial cAMP augments Ca2+ uptake into the organelle to support steroidogenesis
Published in Biochimica et biophysica acta. Bioenergetics (01-09-2018)Get full text
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10
Extramitochondrial OPA1 and adrenocortical function
Published in Molecular and cellular endocrinology (05-12-2013)“…•OPA1 has been detected in the extramitochondrial compartment in H295R cells.•OPA1 does not facilitate cAMP-induced phosphorylation of hormone sensitive…”
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11
Participation of p38 MAPK and a novel-type protein kinase C in the control of mitochondrial Ca2+ uptake
Published in Cell calcium (Edinburgh) (01-03-2008)“…Abstract Angiotensin II elicits cytosolic and mitochondrial Ca2+ signal in H295R adrenocortical cells. We found that Ca2+ uptake rate and peak values in small…”
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12
Effect of cytosolic Mg2+ on mitochondrial Ca2+ signaling
Published in Pflügers Archiv (01-02-2009)“…Cytosolic Ca 2+ signals are followed by mitochondrial Ca 2+ uptake, which, in turn, modifies several biological processes. Mg 2+ is known to inhibit Ca 2+…”
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13
Mitochondrial Ca2+ uptake is inhibited by a concerted action of p38 MAPK and protein kinase D
Published in Cell calcium (Edinburgh) (01-08-2009)“…Abstract Angiotensin II elicits cytosolic Ca2+ signal that is transferred into the mitochondria. Previously we found in H295R cells that this signal transfer…”
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14
Control mechanisms of mitochondrial Ca(2+) uptake - feed-forward modulation of aldosterone secretion
Published in Molecular and cellular endocrinology (28-04-2012)“…Mitochondrial Ca(2+) signal activates metabolism by boosting pyridine nucleotide reduction and ATP synthesis or, if Ca(2+) sequestration is supraphysiological,…”
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15
Reactive oxygen species, Ca2+ signaling and mitochondrial NAD(P)H level in adrenal glomerulosa cells
Published in Cell calcium (Edinburgh) (01-10-2006)“…The acute effects of ultraviolet light, the superoxide-generating xanthine-xanthine oxidase system and H(2)O(2) to on calcium signaling and mitochondrial…”
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16
Mitochondrial cAMP exerts positive feedback on mitochondrial Ca 2+ uptake via the recruitment of Epac1
Published in Journal of cell science (16-05-2018)“…We have previously demonstrated in H295R adrenocortical cells that the Ca -dependent production of mitochondrial cAMP (mt-cAMP) by the matrix soluble adenylyl…”
Get full text
Journal Article -
17
Molecular and Functional Characterization of H.sub.v1 Proton Channel in Human Granulocytes
Published in PloS one (23-11-2010)“…Voltage-gated proton current (I.sub.Hv) has been characterized in several cell types, but the majority of the data was collected in phagocytes, especially in…”
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Journal Article -
18
Mitochondrial Ca 2+ uptake is inhibited by a concerted action of p38 MAPK and protein kinase D
Published in Cell calcium (Edinburgh) (2009)“…Angiotensin II elicits cytosolic Ca 2+ signal that is transferred into the mitochondria. Previously we found in H295R cells that this signal transfer is…”
Get full text
Journal Article -
19
Participation of p38 MAPK and a novel-type protein kinase C in the control of mitochondrial Ca 2+ uptake
Published in Cell calcium (Edinburgh) (2008)“…Angiotensin II elicits cytosolic and mitochondrial Ca 2+ signal in H295R adrenocortical cells. We found that Ca 2+ uptake rate and peak values in small…”
Get full text
Journal Article -
20
Reactive oxygen species, Ca 2+ signaling and mitochondrial NAD(P)H level in adrenal glomerulosa cells
Published in Cell calcium (Edinburgh) (2006)“…The acute effects of ultraviolet light, the superoxide-generating xanthine–xanthine oxidase system and H 2O 2 to on calcium signaling and mitochondrial…”
Get full text
Journal Article