Search Results - "Rajita Sinha"

Chronic Stress, Drug Use, and Vulnerability to Addiction by Sinha, Rajita

“…Stress is a well‐known risk factor in the development of addiction and in addiction relapse vulnerability. A series of population‐based and epidemiological…”
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New Findings on Biological Factors Predicting Addiction Relapse Vulnerability by Sinha, Rajita

“…Relapse is a highly prevalent phenomenon in addiction. This paper examines the new research on identifying biological factors that contribute to addiction…”
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The role of stress in addiction relapse by Sinha, Rajita

“…Stress is an important factor known to increase alcohol and drug relapse risk. This paper examines the stress-related processes that influence addiction…”
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The Effects of Stress on Physical Activity and Exercise by Stults-Kolehmainen, Matthew A., Sinha, Rajita

“…Background Psychological stress and physical activity (PA) are believed to be reciprocally related; however, most research examining the relationship between…”
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Alcohol, stress, and glucocorticoids: From risk to dependence and relapse in alcohol use disorders by Blaine, Sara K., Sinha, Rajita

“…In this review, we detail the clinical evidence supporting the role of psychological and physiological stress in instrumental motivation for alcohol…”
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Psychological and biological resilience modulates the effects of stress on epigenetic aging by Harvanek, Zachary M., Fogelman, Nia, Xu, Ke, Sinha, Rajita

“…Our society is experiencing more stress than ever before, leading to both negative psychiatric and physical outcomes. Chronic stress is linked to negative…”
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Hippocampal seed connectome-based modeling predicts the feeling of stress by Goldfarb, Elizabeth V., Rosenberg, Monica D., Seo, Dongju, Constable, R. Todd, Sinha, Rajita

“…Although the feeling of stress is ubiquitous, the neural mechanisms underlying this affective experience remain unclear. Here, we investigate functional…”
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Dynamic neural activity during stress signals resilient coping by Sinha, Rajita, Lacadie, Cheryl M., Constable, R. Todd, Seo, Dongju

“…Active coping underlies a healthy stress response, but neural processes supporting such resilient coping are not well-known. Using a brief, sustained exposure…”
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Cumulative Adversity and Smaller Gray Matter Volume in Medial Prefrontal, Anterior Cingulate, and Insula Regions by Ansell, Emily B, Rando, Kenneth, Tuit, Keri, Guarnaccia, Joseph, Sinha, Rajita

“…Background Cumulative adversity and stress are associated with risk of psychiatric disorders. While basic science studies show repeated and chronic stress…”
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Origin and Function of Stress-Induced IL-6 in Murine Models by Qing, Hua, Desrouleaux, Reina, Israni-Winger, Kavita, Mineur, Yann S., Fogelman, Nia, Zhang, Cuiling, Rashed, Saleh, Palm, Noah W., Sinha, Rajita, Picciotto, Marina R., Perry, Rachel J., Wang, Andrew

“…Acute psychological stress has long been known to decrease host fitness to inflammation in a wide variety of diseases, but how this occurs is incompletely…”
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Memory biases in alcohol use disorder: enhanced memory for contexts associated with alcohol prospectively predicts alcohol use outcomes by Goldfarb, Elizabeth V, Fogelman, Nia, Sinha, Rajita

“…Memory for prior drinking experiences may powerfully drive later alcohol use in familiar drinking contexts, yet we know little about what patients with alcohol…”
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Stress, cortisol, and other appetite‐related hormones: Prospective prediction of 6‐month changes in food cravings and weight by Chao, Ariana M., Jastreboff, Ania M., White, Marney A., Grilo, Carlos M., Sinha, Rajita

“…Objective To examine whether baseline chronic stress, morning cortisol, and other appetite‐related hormones (leptin, ghrelin, and insulin) predict future…”
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A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment by Wemm, Stephanie E., Larkin, Chloe, Hermes, Gretchen, Tennen, Howard, Sinha, Rajita

“…•Craving increases in response to laboratory stressors which then predicts future alcohol relapse.•It is not known if stressors provoke craving and if…”
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Chronic alcohol-related neural and peripheral stress system dysfunction: Effects on alcohol craving, relapse and recovery by Sinha, Rajita, Ph.D

“…Findings indicate hyperactive basal and neutral state autonomic and hypothalamic-pituitary-adrenal (HPA) axis measures (heart rate, cortisol, cortisol/ACTH…”
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Drug-induced stress responses and addiction risk and relapse by Wemm, Stephanie E., Sinha, Rajita

“…A number of studies have assessed the effects of psychoactive drugs on stress biology, the neuroadaptations resulting from chronic drug use on stress biology,…”
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Sex differences in neural stress responses and correlation with subjective stress and stress regulation by Goldfarb, Elizabeth V., Seo, Dongju, Sinha, Rajita

“…Emotional stress responses, encompassing both stress reactivity and regulation, have been shown to differ between men and women, but the neural networks…”
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Co-Occurring Mental and Substance Use Disorders: The Neurobiological Effects of Chronic Stress by Brady, Kathleen T., Sinha, Rajita

“…The high rate of co-occurrence of substance use disorders and other psychiatric disorders is well established. The population of people with co-occurring…”
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DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations by Liang, Xiaoyu, Justice, Amy C., So-Armah, Kaku, Krystal, John H., Sinha, Rajita, Xu, Ke

“…The process of diagnosing hazardous alcohol drinking (HAD) is based on self-reported data and is thereby vulnerable to bias. There has been an interest in…”
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Sex Differences in Guanfacine Effects on Drug Craving and Stress Arousal in Cocaine-Dependent Individuals by FOX, Helen C, MORGAN, Peter T, SINHA, Rajita

“…Currently, no FDA-approved medication exists for the treatment of cocaine use disorder. Furthermore, as women become increasingly more at risk for the…”
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Enhanced Negative Emotion and Alcohol Craving, and Altered Physiological Responses Following Stress and Cue Exposure in Alcohol Dependent Individuals by SINHA, Rajita, FOX, Helen C, HONG, Kwangik A, BERGQUIST, Keri, BHAGWAGAR, Zubin, SIEDLARZ, Kristen M

“…Chronic alcohol abuse is associated with changes in stress and reward pathways that could alter vulnerability to emotional stress and alcohol craving. This…”
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