Search Results - "Rajic, Jovana"
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Synchrotron-based FTIR microspectroscopy reveals DNA methylation profile in DNA-HALO structure
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2023)“…[Display omitted] •Synchrotron-based FTIR analysis reveals subtle changes in DNA methylation status.•Changes in DNA conformation lead to changes in IR…”
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Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile-The Example of SRXN1 Gene
Published in Antioxidants (20-03-2023)“…The role of catechins in the epigenetic regulation of gene expression has been widely studied; however, if and how this phenomenon relates to the redox…”
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3
Absence of PARP‐1 affects Cxcl12 expression by increasing DNA demethylation
Published in Journal of cellular and molecular medicine (01-04-2019)“…Poly [ADP‐ribose] polymerase 1 (PARP‐1) has an inhibitory effect on C‐X‐C motif chemokine 12 gene (Cxcl12) transcription. We examined whether PARP‐1 affects…”
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α-Lipoic Acid Increases Collagen Synthesis and Deposition in Nondiabetic and Diabetic Rat Kidneys
Published in Oxidative medicine and cellular longevity (2021)“…α-Lipoic acid (ALA) is widely used as a nutritional supplement and therapeutic agent in diabetes management. Well-established antioxidant and hypoglycemic…”
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Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1
Published in Archives of biological sciences (2019)“…Previously, we described the link between C-X-C motif chemokine 12 (Cxcl12) gene induction and DNA hypomethylation in the absence of poly(ADP-ribose)…”
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Association of CXCL12 gene promoter methylation with periodontitis in patients with diabetes mellitus type 2
Published in Archives of oral biology (01-12-2016)“…Highlights • Impairment in periodontal parameters was detected in D/P group relative to P group. • The highest percent of CXCL12 DNA methylation is observed in…”
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CXC chemokine ligand 12α-mediated increase in insulin secretion and survival of mouse pancreatic islets in response to oxidative stress through modulation of calcium uptake
Published in Archives of biological sciences (2018)“…We examined whether CXCL12? improves insulin secretion by influencing the Ca2+ oscillation pattern and Ca2+ influx ([Ca2+]i), thereby enhancing the viability…”
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Oxidative stress-mediated beta cell death and dysfunction as a target for diabetes management
Published in Frontiers in endocrinology (Lausanne) (23-09-2022)“…The biggest drawback of a current diabetes therapy is the treatment of the consequences not the cause of the disease. Regardless of the diabetes type,…”
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Evaluation of the Antidiabetic Potential of Xanthone-Rich Extracts from Gentiana dinarica and Gentiana utriculosa
Published in International journal of molecular sciences (21-08-2024)“…Despite the existence of various therapeutic approaches, diabetes mellitus and its complications have been an increasing burden of mortality and disability…”
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Beneficial Effects of Probiotic Lactobacillus paraplantarum BGCG11 on Pancreatic and Duodenum Function in Diabetic Rats
Published in International journal of molecular sciences (13-07-2024)“…Diabetes mellitus, as a chronic metabolic disorder, significantly impacts the pancreas and among other organs, affects duodenal function. Emerging evidence…”
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DNA methylation of miR-200 clusters promotes epithelial to mesenchymal transition in human conjunctival epithelial cells
Published in Experimental eye research (01-08-2020)“…Epithelial to mesenchymal transition (EMT) contributes to fibrosis associated pathologies including scarring of different ocular tissues. Recently targeting…”
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Centaurium erythraea extract improves survival and functionality of pancreatic beta-cells in diabetes through multiple routes of action
Published in Journal of ethnopharmacology (05-10-2019)“…Centaurium erythraea Rafn (CE) is used as a traditional medicinal plant in Serbia to treat different ailments due to its antidiabetic, antipyretic,…”
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Liposome Encapsulation Enhances the Antidiabetic Efficacy of Silibinin
Published in Pharmaceutics (13-06-2024)“…Silibinin has considerable therapeutic potential for the treatment of diabetes through anti-inflammatory, antioxidant, and immunomodulatory properties…”
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Centaurium erythraea methanol extract improves the functionality of diabetic liver and kidney by mitigating hyperglycemia-induced oxidative stress
Published in Journal of functional foods (01-03-2022)“…[Display omitted] •Persistent oxidative stress leads to the development of diabetic complications.•Centaurium erythraea extract (CEE) reduced protein…”
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15
MENSTRUAL LEAVE AND GENDER EQUALITY
Published in Strani pravni život (01-01-2024)“…Menstrual leave is one of the latest developments in Spanish law. By amending their labour law in order to recognize the right to menstrual leave, Spanish…”
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EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells
Published in Frontiers in endocrinology (Lausanne) (16-03-2023)“…Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presence of polyhormonal cells are main characteristics of diabetes. The…”
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Oral administration of probiotic Lactobacillus paraplantarum BGCG11 attenuates diabetes-induced liver and kidney damage in rats
Published in Journal of functional foods (01-11-2017)“…•Probiotic Lactobacillus paraplantarum BGCG11 showed decreased hyperglycemia in diabetic rats.•The probiotic treatment adjusted the diabetes-induced redox…”
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Centaurium erythraea methanol extract protects red blood cells from oxidative damage in streptozotocin-induced diabetic rats
Published in Journal of ethnopharmacology (18-04-2017)“…Centaurium erythraea Rafn (CE) is a traditional medicinal herb in Serbia with antidiabetic, digestive, antipyretic and antiflatulent effects To investigate the…”
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Chlamydia trachomatis Infection Is Associated with E-Cadherin Promoter Methylation, Downregulation of E-Cadherin Expression, and Increased Expression of Fibronectin and α-SMA-Implications for Epithelial-Mesenchymal Transition
Published in Frontiers in cellular and infection microbiology (14-06-2017)“…( ) can induce scarring disease of the ocular mucosa, known as trachoma, the most common infectious cause of blindness worldwide. We hypothesized that…”
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TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation
Published in Epigenetics & chromatin (05-04-2022)“…Poly(ADP-ribosyl)ation (PARylation), a posttranslational modification introduced by PARP-1 and PARP-2, has first been implicated in DNA demethylation due to…”
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