Search Results - "Rajendra Prasad, Karnam Jayarampillai"
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1
Synthesis of novel benzo naphtho naphthyridines from 2,4‐dicloroquinolines
Published in Journal of heterocyclic chemistry (01-09-2021)“…A schematic study on the condensation of 2,4‐dichloroquinolines (1) with 1‐naphthyamine (2) in the presence of CuI as a catalyst to functionalized mono (3) and…”
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2
Amine-catalyzed direct assembly of indanedione-fused spirobenzo[a]carbazoles from α,α-dicyanomethylidenecarbazoles
Published in Synthetic communications (02-09-2019)“…An unprecedented amine-catalyzed stereoselective reaction of α,α-dicyanomethylidenecarbazoles with indane-1,3-dione and aryl/heteroaryl aldehydes afforded a…”
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3
Microwave‐supported synthesis of pyridocarbazoles
Published in Journal of heterocyclic chemistry (01-10-2022)“…We developed a microwave‐assisted preparation of pyrido[2,3‐c]carbazole from 3‐amino‐9‐ethylcarbazole. The use of microwave heating resulted in shorter…”
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4
Synthesis, antimicrobial, antimycobacterial and structure–activity relationship of substituted pyrazolo-, isoxazolo-, pyrimido- and mercaptopyrimidocyclohepta[ b]indoles
Published in European journal of medicinal chemistry (2012)“…A new class of heterocycles, specifically substituted pyrazolo-, isoxazolo- and pyrimidocyclohepta[ b]indoles, has been prepared by condensation of substituted…”
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5
Synthesis, spectroscopic, in vitro cytotoxicity and crystal structures of novel fluorinated dispiroheterocycles: DFT approach
Published in Monatshefte für Chemie (2018)“…The reaction of azomethine ylide generated in situ from ninhydrin and sarcosine/thiaproline with fluorinated cyclopent[ b ]indole dipolarophiles in refluxing…”
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6
InCl3-catalyzed four-component reaction: a novel synthesis of N-carbazolyl dihydropyridines
Published in Tetrahedron letters (14-12-2011)Get full text
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7
Efficient Synthesis of Functionalized Thienocarbazoles Catalyzed by l‐proline
Published in Journal of heterocyclic chemistry (01-05-2017)“…A new synthetic route has been developed for the synthesis of highly substituted thienocarbazoles via l‐proline mediated Gewald reaction. The approach offers…”
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8
Syntheses of indolo[3,2,1- d,e]phenanthridines and isochromeno[3,4- a] carbazoles: palladium catalyzed intramolecular arylation via C–H functionalization
Published in Tetrahedron letters (09-11-2011)“…A new synthetic route has been developed for the preparation of indolo[3,2,1- d,e]phenanthridines and isochromeno[3,4- a]carbazoles via palladium catalyzed…”
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9
Enhanced Method for the Synthesis and Comprehensive Characterization of 1-(4-Phenylquinolin-2-yl)propan-1-one
Published in ACS omega (21-11-2023)“…We present an enhanced method for synthesizing a novel compound, 1-(4-phenylquinolin-2-yl)propan-1-one (3), through the solvent-free Friedländer quinoline…”
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10
A Regioselective Synthesis of Carbazole‐Appended Dispiropyrrolothiazoles/Pyrrolidines: Synthesis, Computational Studies and In Vitro Anticancer Activity
Published in ChemistrySelect (Weinheim) (06-09-2019)“…Anti‐oncological active carbazole appended dispiroindenoquinoxalinepyrrolothiazoles and dispiroacenaphthylenepyrrolidines were synthesized regioselectively via…”
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11
Efficient synthesis of benzo[h]carbazol[3,2‐b][1,6]naphthyridines
Published in Journal of heterocyclic chemistry (01-07-2022)“…The use of CuI as a promoter to examine amination in the reaction of aminocarbazole (1) and 2‐methyl‐4‐chloroquinoline (2) resulted in a functionalized series…”
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12
Regio- and stereoselective synthesis of dispirooxindole-pyrrolocarbazole hybrids via 1,3-dipolar cycloaddition reactions: Cytotoxic activity and SAR studies
Published in European journal of medicinal chemistry (01-01-2018)“…A library of novel dispiro compounds containing oxindole-pyrrolo-carbazole hybrid frame works has been synthesized in a fully regio- and stereoselective…”
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13
Synthesis of hetero annulated isoxazolo-, pyrido- and pyrimido carbazoles: Screened for in vitro antitumor activity and structure activity relationships, a novel 2-amino-4-(3'-bromo-4'-methoxyphenyl)-8-chloro-11H-pyrimido[4,5-a]carbazole as an antitumor agent
Published in European journal of medicinal chemistry (10-03-2017)“…Claisen-Schmidt condensation of 2,3,4,9-tetrahydro-1H-carbazol-1-one with 3-bromo-4-methoxy benzaldehyde afforded the…”
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14
Solvent-free synthesis of dibenzo[b,j][1,10]phenanthroline derivatives using Eaton's reagent as catalyst
Published in Synthetic communications (19-05-2017)“…A new class of dibenzo[b,j][1,10]phenanthrolines has been prepared. The synthon acridones were achieved in very good yield by a one-pot reaction of…”
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15
Synthesis, spectral analysis and quantum chemical studies on molecular geometry, chemical reactivity of 7-chloro-9-(2′-chlorophenyl)-2,3-dihydroacridin-4(1H)-one and 7-chloro-9-(2′-fluorophenyl)-2,3-dihydroacridin-4(1H)-one
Published in Journal of molecular structure (15-01-2017)“…7-Chloro-9-(2'-chlorophenyl)-2,3-dihydroacridin-4(1H)-one (3a) and 7-chloro-9-(2'-fluorophenyl)-2,3-dihydroacridin-4-(1H)-one (3b) were synthesized from…”
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16
Indium triflate and ionic liquid-mediated Friedländer synthesis of 2-acylquinolines
Published in Synthetic communications (02-11-2017)“…Friedländer synthesis of 2-acylquinolines from the reaction of symmetrical and unsymmetrical 1,2-diketones with 2-aminoarylketones in the presence of indium…”
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17
Rational eco-compatible synthesis and biological screening of new highly functionalized pyrido[2,3- a ]carbazole derivatives: A novel class of antioxidant and anticancer agents
Published in Synthetic communications (18-06-2018)“…A solvent-free, one-pot, and operationally simple protocol was adopted to synthesize a new series of multifunctionalized pyrido[2,3-a]carbazole derivatives…”
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18
Theoretical and experimental investigations on molecular structure of 7-Chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one with cytotoxic studies
Published in Journal of molecular structure (05-04-2016)“…7-Chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one (3) is synthesized from 2-amino-5-chlorobenzophenone (1) and 1,2-cyclohexanedione (2) in the presence of…”
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19
A facile regioselective 1,3-dipolar cycloaddition protocol for the synthesis of new class of quinolinyl dispiro heterocycles
Published in Tetrahedron letters (01-10-2014)“…The 1,3-dipolar cycloaddition reaction of azomethine ylides generated in situ from isatin and secondary amino acids with quinolinyl dipolarophiles in refluxing…”
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20
Design and synthesis of novel pyrrolo[2,3-a]carbazoles: 7-Chloro-2-oxo-3a-(2′-oxo-2′,3′-dihydro-1′H-indol-3′-yl)-2,3,3a,4,5,10-hexahydro-pyrrolo[3,2-a]carbazole-1-carbonitrile as an efficient anticancer agent
Published in European journal of medicinal chemistry (25-04-2018)“…Highly efficient poly functionalized pyrrolo[3,2-a]carbazoles via ring contraction through rearrangement and intramolecular Michael addition reaction using one…”
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