Search Results - "Rajendra, S."

Age-Related Macular Degeneration by Apte, Rajendra S

“…Age-related macular degeneration is the leading cause of vision loss in older persons in industrialized nations. Micronutrient supplementation can reduce the…”
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VEGF in Signaling and Disease: Beyond Discovery and Development by Apte, Rajendra S., Chen, Daniel S., Ferrara, Napoleone

“…The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our understanding of vasculogenesis and angiogenesis during development…”
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Tuning the Electronic Properties of Main-Group Species by N‑Heterocyclic Vinyl (NHV) Scaffolds by Ghadwal, Rajendra S

“…Conspectus Molecules and materials with easily tunable electronic structures and properties are at the forefront of contemporary research. π-Conjugation is…”
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1,3‐Imidazole‐Based Mesoionic Carbenes and Anionic Dicarbenes: Pushing the Limit of Classical N‐Heterocyclic Carbenes by Ghadwal, Rajendra S.

“…Classical N‐heterocyclic carbenes (NHCs) featuring the carbene center at the C2‐position of 1,3‐imidazole framework (i.e. C2‐carbenes) are well acknowledged as…”
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Gene Therapy for Retinal Degeneration by Apte, Rajendra S.

“…Biallelic mutations in the RPE65 gene are associated with inherited retinal degenerations/dystrophies (IRD) and disrupt the visual cycle, leading to loss of…”
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Seed birth to death: dual functions of reactive oxygen species in seed physiology by Kumar, S. P. Jeevan, Prasad, S. Rajendra, Banerjee, Rintu, Thammineni, Chakradhar

“…Reactive oxygen species (ROS) are considered to be detrimental to seed viability. However, recent studies have demonstrated that ROS have key roles in seed…”
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Retinal Imaging as a Predictor of Cognitive Impairment by Apte, Rajendra S

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Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice by Mills, Kathryn F., Yoshida, Shohei, Stein, Liana R., Grozio, Alessia, Kubota, Shunsuke, Sasaki, Yo, Redpath, Philip, Migaud, Marie E., Apte, Rajendra S., Uchida, Koji, Yoshino, Jun, Imai, Shin-ichiro

“…NAD+ availability decreases with age and in certain disease conditions. Nicotinamide mononucleotide (NMN), a key NAD+ intermediate, has been shown to enhance…”
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Structural properties, dielectric relaxation, and impedance spectroscopy of NASICON type Na3+xZr2−xPrxSi2PO12${\rm Na}_{3+x} {\rm Zr}_{2-x} {\rm Pr}_{x} {\rm Si}_2 {\rm PO}_{12}$ ceramics by Meena, Ramcharan, Dhaka, Rajendra S.

“…We investigate the dielectric and impedance spectroscopic investigation of Pr‐doped NASICON type Na3+xZr2−xPrxSi2PO12${\rm Na}_{3+x} {\rm Zr}_{2-x} {\rm…”
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Polyhydrido Copper Clusters: Synthetic Advances, Structural Diversity, and Nanocluster-to-Nanoparticle Conversion by Dhayal, Rajendra S, van Zyl, Werner E, Liu, C. W

“…Metal hydride clusters have historically been studied to unravel their aesthetically pleasing molecular structures and interesting properties, especially…”
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Reducing Treatment Burden in AMD by Apte, Rajendra S.

“…VEGF-A antagonists have revolutionized wet AMD treatment. Several challenges remain including high treatment burden requiring repeated intraocular injections…”
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Greener Route for Synthesis of aryl and alkyl-14H-dibenzo [a.j] xanthenes using Graphene Oxide-Copper Ferrite Nanocomposite as a Recyclable Heterogeneous Catalyst by Kumar, Aniket, Rout, Lipeeka, Achary, Lakkoji Satish Kumar, Dhaka, Rajendra. S., Dash, Priyabrat

“…A facile, efficient and environmentally-friendly protocol for the synthesis of xanthenes by graphene oxide based nanocomposite (GO-CuFe 2 O 4 ) has been…”
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Seeing through VEGF: innate and adaptive immunity in pathological angiogenesis in the eye by Sene, Abdoulaye, Chin-Yee, David, Apte, Rajendra S

“…Highlights • Vascular endothelial growth factor (VEGF) in eye diseases. • Immune regulation of pathological neovascularization. • VEGF-independent therapies in…”
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Dichlorosilylene: A High Temperature Transient Species to an Indispensable Building Block by Ghadwal, Rajendra S, Azhakar, Ramachandran, Roesky, Herbert W

“…Isolating stable compounds with low-valent main group elements have long been an attractive research topic, because several of these compounds can mimic…”
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Pd/C-Catalyzed Aminocarbonylation of Aryl Iodides via Oxidative C–N Bond Activation of Tertiary Amines to Tertiary Amides by Mane, Rajendra S, Bhanage, Bhalchandra M

“…This work reports oxidative N-dealkylation/carbonylation of tertiary amines to tertiary amides by using molecular oxygen as a sole oxidant using a Pd/C…”
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Sourcing Photoreceptor-like Cells for Treating Vision Loss by Apte, Rajendra S

“…Loss of retinal photoreceptor cells is a critical event in loss of vision. A new, albeit tentative, strategy to rectify the loss of photoreceptor cells…”
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Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice by Yoshida, Mitsukuni, Satoh, Akiko, Lin, Jonathan B., Mills, Kathryn F., Sasaki, Yo, Rensing, Nicholas, Wong, Michael, Apte, Rajendra S., Imai, Shin-ichiro

“…Aging is a significant risk factor for impaired tissue functions and chronic diseases. Age-associated decline in systemic NAD+ availability plays a critical…”
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NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice by Lin, Jonathan B., Kubota, Shunsuke, Ban, Norimitsu, Yoshida, Mitsukuni, Santeford, Andrea, Sene, Abdoulaye, Nakamura, Rei, Zapata, Nicole, Kubota, Miyuki, Tsubota, Kazuo, Yoshino, Jun, Imai, Shin-ichiro, Apte, Rajendra S.

“…Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for…”
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Population structure and genetic diversity characterization of soybean for seed longevity by T V, Naflath, S, Rajendra Prasad, R L, Ravikumar

“…Seed longevity is an important trait in the context of germplasm conservation and economics of seed production. The identification of populations with high…”
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Lewis Base Stabilized Dichlorosilylene by Ghadwal, Rajendra S, Roesky, Herbert W, Merkel, Sebastian, Henn, Julian, Stalke, Dietmar

“…Stable? You can bottle it! The base‐stabilized dichlorosilylene L1SiCl2 (see picture; L1=1,3‐bis(2,6‐diisopropylphenyl)imidazol‐2‐ylidene) is stable at room…”
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