Search Results - "Raje, Vidisha"

Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight by Gaykema, Ronald P, Newmyer, Brandon A, Ottolini, Matteo, Raje, Vidisha, Warthen, Daniel M, Lambeth, Philip S, Niccum, Maria, Yao, Ting, Huang, Yiru, Schulman, Ira G, Harris, Thurl E, Patel, Manoj K, Williams, Kevin W, Scott, Michael M

“…Peptides derived from pre-proglucagon (GCG peptides) act in both the periphery and the CNS to change food intake, glucose homeostasis, and metabolic rate while…”
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Adipocyte lipolysis drives acute stress-induced insulin resistance by Raje, Vidisha, Ahern, Katelyn W., Martinez, Brittany A., Howell, Nancy L., Oenarto, Vici, Granade, Mitchell E., Kim, Jae Woo, Tundup, Smanla, Bottermann, Katharina, Gödecke, Axel, Keller, Susanna R., Kadl, Alexandra, Bland, Michelle L., Harris, Thurl E.

“…Stress hyperglycemia and insulin resistance are evolutionarily conserved metabolic adaptations to severe injury including major trauma, burns, or hemorrhagic…”
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Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes by Mullins, Garrett R., Wang, Lifu, Raje, Vidisha, Sherwood, Samantha G., Grande, Rebecca C., Boroda, Salome, Eaton, James M., Blancquaert, Sara, Roger, Pierre P., Leitinger, Norbert, Harris, Thurl E.

“…Anabolic and catabolic signaling oppose one another in adipose tissue to maintain cellular and organismal homeostasis, but these pathways are often deregulated…”
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Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity by Derecka, Marta, Gornicka, Agnieszka, Koralov, Sergei B., Szczepanek, Karol, Morgan, Magdalena, Raje, Vidisha, Sisler, Jennifer, Zhang, Qifang, Otero, Dennis, Cichy, Joanna, Rajewsky, Klaus, Shimoda, Kazuya, Poli, Valeria, Strobl, Birgit, Pellegrini, Sandra, Harris, Thurl E., Seale, Patrick, Russell, Aaron P., McAinch, Andrew J., O’Brien, Paul E., Keller, Susanna R., Croniger, Colleen M., Kordula, Tomasz, Larner, Andrew C.

“…Mice lacking the Jak tyrosine kinase member Tyk2 become progressively obese due to aberrant development of Myf5+ brown adipose tissue (BAT). Tyk2 RNA levels in…”
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The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes by Sisler, Jennifer D, Morgan, Magdalena, Raje, Vidisha, Grande, Rebecca C, Derecka, Marta, Meier, Jeremy, Cantwell, Marc, Szczepanek, Karol, Korzun, William J, Lesnefsky, Edward J, Harris, Thurl E, Croniger, Colleen M, Larner, Andrew C

“…The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes…”
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Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists by Boroda, Salome, Niccum, Maria, Raje, Vidisha, Purow, Benjamin W., Harris, Thurl E.

“…[Display omitted] Diacylglycerol kinase alpha (DGKα) catalyzes the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). Recently, DGKα was identified…”
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Oxidized neutral lipid lipolysis regulates insulin signaling during acute stress by Ahern, Katelyn, Mullins, Garrett, Raje, Vidisha, Granade, Mitchell, Harris, Thurl

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Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production by Meier, Jeremy A, Hyun, Moonjung, Cantwell, Marc, Raza, Ali, Mertens, Claudia, Raje, Vidisha, Sisler, Jennifer, Tracy, Erin, Torres-Odio, Sylvia, Gispert, Suzana, Shaw, Peter E, Baumann, Heinz, Bandyopadhyay, Dipankar, Takabe, Kazuaki, Larner, Andrew C

“…Signal transducer and activator of transcription 3 (STAT3) is associated with various physiological and pathological functions, mainly as a transcription…”
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Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727 by Zhang, Qifang, Raje, Vidisha, Yakovlev, Vasily A., Yacoub, Adly, Szczepanek, Karol, Meier, Jeremy, Derecka, Marta, Chen, Qun, Hu, Ying, Sisler, Jennifer, Hamed, Hossein, Lesnefsky, Edward J., Valerie, Kristoffer, Dent, Paul, Larner, Andrew C.

“…Signal transducer and activator of transcription 3 (Stat3) is a key mediator in the development of many cancers. For 20 years, it has been assumed that Stat3…”
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Cardiomyocyte p38 MAPKα suppresses a heart–adipose tissue–neutrophil crosstalk in heart failure development by Bottermann, Katharina, Kalfhues, Lisa, Nederlof, Rianne, Hemmers, Anne, Leitner, Lucia M., Oenarto, Vici, Nemmer, Jana, Pfeffer, Mirjam, Raje, Vidisha, Deenen, Rene, Petzsch, Patrick, Zabri, Heba, Köhrer, Karl, Reichert, Andreas S., Grandoch, Maria, Fischer, Jens W., Herebian, Diran, Stegbauer, Johannes, Harris, Thurl E., Gödecke, Axel

“…Although p38 MAP Kinase α (p38 MAPKα) is generally accepted to play a central role in the cardiac stress response, to date its function in maladaptive cardiac…”
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Kinase inactive Tyrosine kinase (Tyk2) Supports Differentiation of Brown fat Cells by Raje, Vidisha, Derecka, Marta, Cantwell, Marc, Meier, Jeremy, Szczepanek, Karol, Sisler, Jennifer D, Strobl, Birgit, Gamero, Ana, Harris, Thurl E, Larner, Andrew C

“…It has been known for decades that brown adipose tissue plays a central role in maintaining body temperature in hibernating animals, and human infants…”
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STAT3 suppresses Wnt/β-catenin signaling during the induction phase of primary Myf5+ brown adipogenesis by Cantwell, Marc T., Farrar, Jared S., Lownik, Joseph C., Meier, Jeremy A., Hyun, Moonjung, Raje, Vidisha, Waters, Michael R., Celi, Francesco S., Conrad, Daniel H., Harris, Thurl E., Larner, Andrew C.

“…•STAT3 is required during the induction phase for differentiation of primary brown pre-adipocytes.•Deletion of STAT3 after the induction period does not affect…”
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Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight by Gaykema, Ronald P, Newmyer, Brandon A, Ottolini, Matteo, Raje, Vidisha, Warthen, Daniel M, Lambeth, Philip S, Niccum, Maria, Yao, Ting, Huang, Yiru, Schulman, Ira G, Harris, Thurl E, Patel, Manoj K, Williams, Kevin W, Scott, Michael M

“…Peptides derived from pre-proglucagon (GCG peptides) act in both the periphery and the CNS to change food intake, glucose homeostasis, and metabolic rate while…”
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247 by Sisler, Jennifer, Szelag, Magdalena, Raje, Vidisha, Derecka, Marta, Szczepanek, Karol, Lesnefsky, Edward, Larner, Andrew C.

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The Role of Tyk2 in Regulating Energy Expenditure and Preventing Obesity by Raje, Vidisha B, Derecka, Marta, Gornicka, Agnieszka, Sczepanek, Karol, Sisler, Jennifer, Croniger, Colleen M, Larner, Andrew

“…Abstract only Brown adipose tissue(BAT) and skeletal muscle(SKM) are the two major tissues involved in energy expenditure, mediated by thermogenesis. We have…”
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247 : Stat1 inhibits mitochondrial biogenesis by Sisler, Jennifer, Szelag, Magdalena, Raje, Vidisha, Derecka, Marta, Szczepanek, Karol, Lesnefsky, Edward, Larner, Andrew C.

“…Stat1 plays a central role in orchestrating responses to a variety of pathogens by activating the transcription of nuclear encoded genes that mediate the…”
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The JAK kinase Tyk2 and the Signal Transducer and Activator of Transcription 3 (Stat3) are required for Brown Adipose Tissue Differentiation by Larner, Andrew Charles, Derecka, Marta, Gornicka, Agnieszka, Szczepanek, Karol, Morgan, Magdalena, Raje, Vidisha, Sisler, Jennifer, Keller, Susanna

“…Abstract only Type II diabetes, cardiovascular disease, non‐alcoholic fatty liver disease and Alzheimer's disease are some of the numerous disorders associated…”
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Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists by Boroda, Salome, Niccum, Maria, Raje, Vidisha, Purow, Benjamin W, Harris, Thurl E

“…Diacylglycerol kinase alpha (DGKα) catalyzes the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). Recently, DGKα was identified as a therapeutic…”
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Role of Tyk2 in regulating energy expenditure and preventing obesity by Raje, Vidisha Bipin

“…Obesity develops when energy intake exceeds energy expenditure. Defect in the function of brown fat and skeletal muscle, two of the major tissues that…”
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