Search Results - "Rajcula, Matthew J"

The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice by Lehrke, Michael Jonathan, Shapiro, Michael Jeremy, Rajcula, Matthew J, Kennedy, Madeleine M, McCue, Shaylene A, Medina, Kay L, Shapiro, Virginia Smith

“…Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are…”
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Histone deacetylase 3 represses cholesterol efflux during CD4 + T-cell activation by Wilfahrt, Drew, Philips, Rachael L, Lama, Jyoti, Kizerwetter, Monika, Shapiro, Michael Jeremy, McCue, Shaylene A, Kennedy, Madeleine M, Rajcula, Matthew J, Zeng, Hu, Shapiro, Virginia Smith

“…After antigenic activation, quiescent naive CD4 T cells alter their metabolism to proliferate. This metabolic shift increases production of nucleotides, amino…”
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Cutting Edge: ST8Sia6-Generated α-2,8-Disialic Acids Mitigate Hyperglycemia in Multiple Low-Dose Streptozotocin-Induced Diabetes by Belmonte, Paul J, Shapiro, Michael J, Rajcula, Matthew J, McCue, Shaylene A, Shapiro, Virginia Smith

“…The immune system contains a series of checks and balances that maintain tolerance and prevent autoimmunity. Sialic acid-binding Ig-type lectins (Siglecs) are…”
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Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor-Induced Cell Death by Philips, Rachael L, McCue, Shaylene A, Rajcula, Matthew J, Shapiro, Virginia S

“…Intricate life-versus-death decisions are programmed during T cell development, and the regulatory mechanisms that coordinate their activation and repression…”
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Murine T Cell Maturation Entails Protection from MBL2, but Complement Proteins Do Not Drive Clearance of Cells That Fail Maturation in the Absence of NKAP by Dash, Barsha, Belmonte, Paul J, Fine, Sydney R, Shapiro, Michael J, Chung, Ji Young, Schwab, Aaron D, McCue, Shaylene A, Rajcula, Matthew J, Shapiro, Virginia Smith

“…Recent thymic emigrants that fail postpositive selection maturation are targeted by complement proteins. T cells likely acquire complement resistance during…”
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The Interaction between NKAP and HDAC3 Is Critical for T Cell Maturation by Dash, Barsha, Shapiro, Michael J, Thapa, Puspa, Romero Arocha, Sinibaldo, Chung, Ji-Young, Schwab, Aaron D, McCue, Shaylene A, Rajcula, Matthew J, Shapiro, Virginia Smith

“…NKAP and HDAC3 are critical for T cell maturation. NKAP and HDAC3 physically associate, and a point mutation in NKAP, NKAP(Y352A), abrogates this interaction…”
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ST8Sia6 generated alpha-2,8-disialic acids mitigate hyperglycemia in multiple low dose streptozotocin-induced diabetes by Belmonte, Paul J., Shapiro, Michael J., Rajcula, Matthew J., McCue, Shaylene A., Shapiro, Virginia Smith

“…The immune system contains a series of checks and balances that maintain tolerance and prevent autoimmunity. Siglecs (Sialic acid-binding immunoglobulin type…”
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HDAC3 protects DP thymocytes from P2X7 receptor-induced cell death by Philips, Rachael L., McCue, Shaylene A., Rajcula, Matthew J., Shapiro, Virginia S.

“…Intricate life-versus-death decisions are programmed during T cell development, and the regulatory mechanisms that coordinate their activation and repression…”
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Histone deacetylase 3 represses cholesterol efflux during CD4.sup.+ T-cell activation by Wilfahrt, Drew, Philips, Rachael L, Lama, Jyoti, Kizerwetter, Monika, Shapiro, Michael Jeremy, McCue, Shaylene A, Kennedy, Madeleine M, Rajcula, Matthew J, Zeng, Hu, Shapiro, Virginia Smith

“…After antigenic activation, quiescent naive CD4.sup.+ T cells alter their metabolism to proliferate. This metabolic shift increases production of nucleotides,…”
Get full text