Search Results - "Rajasethupathy, Priyamvada"

A Role for Neuronal piRNAs in the Epigenetic Control of Memory-Related Synaptic Plasticity by Rajasethupathy, Priyamvada, Antonov, Igor, Sheridan, Robert, Frey, Sebastian, Sander, Chris, Tuschl, Thomas, Kandel, Eric R.

“…Small RNA-mediated gene regulation during development causes long-lasting changes in cellular phenotypes. To determine whether small RNAs of the adult brain…”
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Projections from neocortex mediate top-down control of memory retrieval by Rajasethupathy, Priyamvada, Sankaran, Sethuraman, Marshel, James H., Kim, Christina K., Ferenczi, Emily, Lee, Soo Yeun, Berndt, Andre, Ramakrishnan, Charu, Jaffe, Anna, Lo, Maisie, Liston, Conor, Deisseroth, Karl

“…Top-down prefrontal cortex inputs to the hippocampus have been hypothesized to be important in memory consolidation, retrieval, and the pathophysiology of…”
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Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution by Sylwestrak, Emily Lauren, Rajasethupathy, Priyamvada, Wright, Matthew Arnot, Jaffe, Anna, Deisseroth, Karl

“…In recently developed approaches for high-resolution imaging within intact tissue, molecular characterization over large volumes has been largely restricted to…”
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Neural activity ramps in frontal cortex signal extended motivation during learning by Regalado, Josue M, Corredera Asensio, Ariadna, Haunold, Theresa, Toader, Andrew C, Li, Yan Ran, Neal, Lauren A, Rajasethupathy, Priyamvada

“…Learning requires the ability to link actions to outcomes. How motivation facilitates learning is not well understood. We designed a behavioral task in which…”
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Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB by Rajasethupathy, Priyamvada, Fiumara, Ferdinando, Sheridan, Robert, Betel, Doron, Puthanveettil, Sathyanarayanan V., Russo, James J., Sander, Chris, Tuschl, Thomas, Kandel, Eric

“…Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small regulatory…”
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Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain by Nandi, Sayan, Chandramohan, Dhruva, Fioriti, Luana, Melnick, Ari M., Hébert, Jean M., Mason, Christopher E., Rajasethupathy, Priyamvada, Kandel, Eric R.

“…Piwi-interacting RNAs (piRNAs), long thought to be restricted to germline, have recently been discovered in neurons of Aplysia, with a role in the epigenetic…”
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MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets by Fiumara, Ferdinando, Rajasethupathy, Priyamvada, Antonov, Igor, Kosmidis, Stylianos, Sossin, Wayne S., Kandel, Eric R.

“…The maintenance phase of memory-related long-term facilitation (LTF) of synapses between sensory and motor neurons of the gill-withdrawal reflex of Aplysia…”
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strategy to capture and characterize the synaptic transcriptome by Puthanveettil, Sathyanarayanan V., Antonov, Igor, Kalachikov, Sergey, Rajasethupathy, Priyamvada, Choi, Yun-Beom, Kohn, Andrea B., Citarella, Mathew, Yu, Fahong, Karl, Kevin A., Kinet, Maxime, Morozova, Irina, Russo, James J., Ju, Jingyue, Moroz, Leonid L., Kandel, Eric R.

“…Here we describe a strategy designed to identify RNAs that are actively transported to synapses during learning. Our approach is based on the characterization…”
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Targeting Neural Circuits by Rajasethupathy, Priyamvada, Ferenczi, Emily, Deisseroth, Karl

“…Optogenetic methodology enables direct targeting of specific neural circuit elements for inhibition or excitation while spanning timescales from the acute…”
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Prefrontal feature representations drive memory recall by Yadav, Nakul, Noble, Chelsea, Niemeyer, James E., Terceros, Andrea, Victor, Jonathan, Liston, Conor, Rajasethupathy, Priyamvada

“…Memory formation involves binding of contextual features into a unitary representation 1 – 4 , whereas memory recall can occur using partial combinations of…”
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New mechanisms in memory storage: piRNAs and epigenetics by Landry, Christopher D, Kandel, Eric R, Rajasethupathy, Priyamvada

“…Highlights • Epigenetics offers new insights into mechanisms of long-term memory storage. • What provides spatiotemporal specificity of epigenetic regulation…”
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Targeting circuits by Rajasethupathy, Priyamvada, Ferenczi, Emily, Deisseroth, Karl

“…Current optogenetic methodology enables precise inhibition or excitation of neural circuits, spanning timescales as needed from the acute (milliseconds) to the…”
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Neural activity ramps in frontal cortex signal extended motivation during learning by Regalado, Josue M, Corredera Asensio, Ariadna, Haunold, Theresa, Toader, Andrew C, Li, Yan Ran, Neal, Lauren A, Rajasethupathy, Priyamvada

“…Learning requires the ability to link actions to outcomes. How motivation facilitates learning is not well understood. We designed a behavioral task in which…”
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A Thalamic Orphan Receptor Drives Variability in Short-Term Memory by Hsiao, Kuangfu, Noble, Chelsea, Pitman, Wendy, Yadav, Nakul, Kumar, Suraj, Keele, Gregory R., Terceros, Andrea, Kanke, Matt, Conniff, Tara, Cheleuitte-Nieves, Christopher, Tolwani, Ravi, Sethupathy, Praveen, Rajasethupathy, Priyamvada

“…Working memory is a form of short-term memory that involves maintaining and updating task-relevant information toward goal-directed pursuits. Classical models…”
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Systems modeling: a pathway to drug discovery by Rajasethupathy, Priyamvada, Vayttaden, Sharat J, Bhalla, Upinder S

“…Systems modeling is emerging as a valuable tool in therapeutics. This is seen by the increasing use of clinically relevant computational models and a rise in…”
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Novel Small-RNA Mediated Gene-Regulatory Mechanisms for Long-term Memory by Rajasethupathy, Priyamvada

“…Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small RNAs in…”
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Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB by Rajasethupathy, Priyamvada, Fiumara, Ferdinando, Sheridan, Robert, Betel, Doron, Puthanveettil, Sathyanarayanan V, Russo, James J, Sander, Chris, Tuschl, Thomas, Kandel, Eric

“…Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small regulatory…”
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Selection of Stable RNA Molecules that Can Regulate the Channel-Opening Equilibrium of the Membrane-Bound γ-Aminobutyric Acid Receptor by Cui, Yang, Rajasethupathy, Priyamvada, Hess, George P

“…The γ-aminobutyric acid (GABAA) receptor belongs to a superfamily of membrane-bound proteins that regulate signal transmission between cells in the nervous…”
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