Search Results - "Rajasekaran, Subbiah"

Anti-asthmatic effects of tannic acid from Chinese natural gall nuts in a mouse model of allergic asthma by Rajasekar, Nandhine, Sivanantham, Ayyanar, Kar, Amrita, Mukhopadhyay, Sramana, Mahapatra, Santanu Kar, Paramasivam, Sudhakar Gandhi, Rajasekaran, Subbiah

“…[Display omitted] •Tannic acid (TA) is a class of polyphenol that is present in higher plants.•AHR and airway inflammation in OVA-induced asthmatic mice were…”
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C-phycocyanin suppresses transforming growth factor-β1-induced epithelial mesenchymal transition in human epithelial cells by Pattarayan, Dhamotharan, Rajarajan, Dheeran, Ayyanar, Sivanantham, Palanichamy, Rajaguru, Subbiah, Rajasekaran

“…Epithelial mesenchymal transition (EMT) is a process through which epithelial cells undergo multiple biochemical changes, causing them to differentiate into a…”
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MicroRNA-16 Represses TGF-β1-induced Epithelial-to-Mesenchymal Transition in Human Lung Adenocarcinoma Cell Line by Rajasekaran, Subbiah, Mishra, Sehal, Gandhi, Deepa

“…The transforming growth factor-beta1 (TGF-β1)-induced epithelial-tomesenchymal transition (EMT) has a crucial effect on the progression and metastasis of lung…”
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Design, synthesis, and characterization of α, β‐unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic modulators in human non‐small cell lung cancer A549 cell line by Chidambaram, Anusha, Sundararaju, Kavya, Chidambaram, Ramesh K., Subbiah, Rajasekaran, Jayaraj, John M., Muthusamy, Karthikeyan, Vilwanathan, Ravikumar

“…Histone deacetylase inhibitors (HDACi) are a small molecule chemotherapeutics that target the chromatin remodeling through the regulation of histone and…”
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Fra-1/AP-1 transcription factor negatively regulates pulmonary fibrosis in vivo by Rajasekaran, Subbiah, Vaz, Michelle, Reddy, Sekhar P

“…The Fra-1/AP-1 transcription factor plays a key role in tumor epithelial cell progression; however, its role in pathogenic lung fibrosis remains unclear. In…”
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Therapeutic potential of plant-derived tannins in non-malignant respiratory diseases by Rajasekaran, Subbiah, Rajasekar, Nandhine, Sivanantham, Ayyanar

“…Respiratory diseases are the major cause of human illness and death around the world. Despite advances in detection and treatment, very few classes of safe and…”
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The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis by Subbiah, Rajasekaran, Tiwari, Rajnarayan R.

“…The herbicide paraquat (PQ; 1,1'-dimethyl-4,4'-bipyridylium dichloride) is a highly toxic organic heterocyclic herbicide that has been widely used in…”
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An overview on the role of plant-derived tannins for the treatment of lung cancer by Rajasekar, Nandhine, Sivanantham, Ayyanar, Ravikumar, Vilwanathan, Rajasekaran, Subbiah

“…Lung cancer is the leading cause of cancer-related death globally. Despite many advanced approaches to treat cancer, they are often ineffective due to…”
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The impact of environmental and occupational exposures of manganese on pulmonary, hepatic, and renal functions by Gandhi, Deepa, Rudrashetti, Ashwinkumar P., Rajasekaran, Subbiah

“…Manganese (Mn) is an essential trace element for humans, but long‐term environmental or occupational exposures can lead to numerous health problems. Although…”
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MicroRNA-195-5p mediates arsenic-induced cytotoxicity in human lung epithelial cells: Beneficial role of plant-derived tannic acid by Mishra, Sehal, Kalra, Neetu, Botlagunta, Mahendran, Rajasekaran, Subbiah

“…Arsenic (As), a highly toxic metalloid, which causes environmental lung diseases and affects millions of people worldwide. Respiratory epithelial cells are…”
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Repurposing of histone deacetylase inhibitors: A promising strategy to combat pulmonary fibrosis promoted by TGF-β signalling in COVID-19 survivors by P, Krishna Murthy, Sivashanmugam, Karthikeyan, Kandasamy, Mahesh, Subbiah, Rajasekaran, Ravikumar, Vilwanathan

“…Coronavirus disease 2019 (COVID-19) has rapidly spread around the world causing global public health emergency. In the last twenty years, we have witnessed…”
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Tannic acid attenuates TGF‐β1‐induced epithelial‐to‐mesenchymal transition by effectively intervening TGF‐β signaling in lung epithelial cells by Pattarayan, Dhamotharan, Sivanantham, Ayyanar, Krishnaswami, Venkateshwaran, Loganathan, Lakshmanan, Palanichamy, Rajaguru, Natesan, Subramanian, Muthusamy, Karthikeyan, Rajasekaran, Subbiah

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and an irreversible lung disorder characterized by the accumulation of fibroblasts and…”
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MicroRNA Regulation of Acute Lung Injury and Acute Respiratory Distress Syndrome by Rajasekaran, Subbiah, Pattarayan, Dhamotharan, Rajaguru, P., Sudhakar Gandhi, P. S., Thimmulappa, Rajesh K.

“…The acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI), is a very common condition associated with critically ill patients,…”
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Acute promyelocytic leukaemia with PML - RAR a fusion presenting as pancytopenia and atypical morphology: A case report by Krishna, Sai, Hussain, Nazia, Subbiah, Rajasekaran

“…Acute myeloid leukaemia (AML) is characterised by uncontrolled proliferation of malignant marrow stem cells and is associated with infection, anaemia and…”
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Plant Isoquinoline Alkaloid Berberine Exhibits Chromatin Remodeling by Modulation of Histone Deacetylase To Induce Growth Arrest and Apoptosis in the A549 Cell Line by Kalaiarasi, Arunachalam, Anusha, Chidambaram, Sankar, Renu, Rajasekaran, Subbiah, John Marshal, Jayaraj, Muthusamy, Karthikeyan, Ravikumar, Vilwanathan

“…Histone deacetylases (HDACs) are a group of epigenetic enzymes that control gene expression through their repressive influence on histone deacetylation…”
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Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK by Sivanantham, Ayyanar, Pattarayan, Dhamotharan, Bethunaickan, Ramalingam, Kar, Amrita, Mahapatra, Santanu Kar, Thimmulappa, Rajesh K., Palanichamy, Rajaguru, Rajasekaran, Subbiah

“…Acute lung injury (ALI) and its severe form acute respiratory distress syndrome (ARDS) remain a major cause of morbidity and mortality in critically ill…”
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Activation of ERK/NF-kB Pathways Contributes to the Inflammatory Response in Epithelial Cells and Macrophages Following Manganese Exposure by Gandhi, Deepa, Bhandari, Sneha, Maity, Sangita, Mahapatra, Santanu Kar, Rajasekaran, Subbiah

“…Different types of metals, including manganese (Mn), are constantly encountered in various environmental matrices due to natural and anthropogenic activities…”
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Tannic acid modulates fibroblast proliferation and differentiation in response to pro‐fibrotic stimuli by Pattarayan, Dhamotharan, Sivanantham, Ayyanar, Bethunaickan, Ramalingam, Palanichamy, Rajaguru, Rajasekaran, Subbiah

“…In response to tissue injury, fibroblasts migrate into the wound, where they undergo proliferation and differentiation. The persistence of these differentiated…”
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Non-malignant respiratory illness associated with exposure to arsenic compounds in the environment by Gandhi, Deepa, Bhandari, Sneha, Mishra, Sehal, Tiwari, Rajnarayan R., Rajasekaran, Subbiah

“…Arsenic (As), a toxic metalloid, primarily originates from both natural and anthropogenic activities. Reports suggested that millions of people globally…”
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Diagnostic Potential of Extracellular MicroRNA in Respiratory Diseases by Pattarayan, Dhamotharan, Thimmulappa, Rajesh K., Ravikumar, Vilwanathan, Rajasekaran, Subbiah

“…Lack of markers of subclinical disease state and clinical phenotype other than pulmonary function test has made the diagnosis and interventions of…”
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