Search Results - "Rajapakse, S."

Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review by Rodrigo, C., Fernando, S.D., Rajapakse, S.

“…Repurposing hydroxychloroquine (HCQ) and chloroquine (CQ) as antiviral agents is a re-emerging topic with the advent of new viral epidemics. To summarize…”
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The Effect of Inflammation on Bone by Epsley, Scott, Tadros, Samuel, Farid, Alexander, Kargilis, Daniel, Mehta, Sameer, Rajapakse, Chamith S

“…Bone remodeling is the continual process to renew the adult skeleton through the sequential action of osteoblasts and osteoclasts. Nuclear factor RANK, an…”
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Assessment of the multifactorial causes of atypical femoral fractures using a novel multiscale finite element approach by Demirtas, Ahmet, Rajapakse, Chamith S., Ural, Ani

“…Atypical femoral fracture (AFF), which is a low energy fracture in the subtrochanteric or diaphysis region of the femur, has multifactorial causes that span…”
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Thromboprophylaxis: striking a balance between under-treatment and over-treatment by Rajapakse, S

“…Venous thromboembolism (VTE) is an important cause of morbidity and mortality among patients admitted to hospital. Pulmonary embolism results in 5-10% of…”
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Current thinking about the management of dysfunction of the temporomandibular joint: a review by Rajapakse, S, Ahmed, N, Sidebottom, A.J

“…Abstract Increasingly the management of TMJ pathology is becoming a subspecialist interest. The number of patients having TMJ joint replacement had steadily…”
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Allied health in-reach in the emergency department: does it reduce length of stay? by Rajapakse, S

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Amphotericin B for treatment of visceral leishmaniasis: systematic review and meta-analysis of prospective comparative clinical studies including dose-ranging studies by Rodrigo, C., Weeratunga, P., Fernando, S.D., Rajapakse, S.

“…To evaluate the evidence for use of different formulations of amphotericin B (AmB), minimum effective dose for each formulation and its comparative efficacy…”
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Reactive oxygen species in endothelial signaling in COVID-19: Protective role of the novel peptide PIP-2 by Paul, Oindrila, Akolia, Isha K, Qin Tao, Jian, Jain, Nikita, Louneva, Natalia, Montone, Kathleen T, Fisher, Aron B, Rajapakse, Chamith S, Bermudez, Christian, Chatterjee, Shampa

“…Recent research suggests that endothelial activation plays a role in coronavirus disease 2019 (COVID-19) pathogenesis by promoting a pro-inflammatory state…”
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Association of pharmacogenomic, clinical and behavioural factors with oral levothyroxine (LT-4) dose of hypothyroid patients in Sri Lanka: a matched case control study by Dalugodage, S S, Bowatte, Gayan, Antonypillai, Charles, Rajapakse, S, Tennakoon, T M I U K

“…Hypothyroidism is a common endocrine disorder that exerts a substantial influence on people all over the world. Levothyroxine (LT-4) is the drug of choice for…”
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High serum levels of reactive nitrogen species and low total antioxidant capacity in patients with resistant hypertension compared to those in age- gender matched healthy controls, controlled hypertension and follow up with propranolol treatment in the extended APPROPRIATE trial by Ranasinghe, H N, Weeratunga, P N, Fernando, N, Katulanda, P, Rajapakse, S, Galappatthy, P, Handunnetti, S M, Constantine, G R

“…To perform a comparative analysis of the extended APPROPRIATE trial of measures of reactive nitrogen species and antioxidant capacity in patients having…”
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Atherogenic Indices as a Predictor of Aortic Calcification in Prostate Cancer Patients Assessed Using 18F-Sodium Fluoride PET/CT by Dai, Michelle, Xu, Winnie, Chesnais, Helene, Anabaraonye, Nancy, Parente, James, Chatterjee, Shampa, Rajapakse, Chamith S.

“…A major pathophysiological cause of cardiovascular disease is vascular plaque calcification. Fluorine 18–Sodium Fluoride (18F-NaF) PET/CT can be used as a…”
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Diagnosing and predicting outcome in leptospirosis: the need for clinically relevant basic sciences research by Rajapakse, S

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Imaging Atherosclerosis by PET, With Emphasis on the Role of FDG and NaF as Potential Biomarkers for This Disorder by Mayer, Michael, Borja, Austin J., Hancin, Emily C., Auslander, Thomas, Revheim, Mona-Elisabeth, Moghbel, Mateen C., Werner, Thomas J., Alavi, Abass, Rajapakse, Chamith S.

“…Molecular imaging has emerged in the past few decades as a novel means to investigate atherosclerosis. From a pathophysiological perspective, atherosclerosis…”
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Shared contributions of the head and torso to spatial reference frames across spatial judgments by Longo, Matthew R., Rajapakse, Sampath S., Alsmith, Adrian J.T., Ferrè, Elisa R.

“…Egocentric frames of reference take the body as the point of origin of a spatial coordinate system. Bodies, however, are not points, but extended objects, with…”
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A Unique Challenge in Management in the Emergency Department and Cardiac Cathlab: Case Review of Two Subjects with Kounis Syndrome Complicated with ST Elevation Myocardial Infarction and Ventricular Tachycardia, Following Exposure to Cutaneous or Intravenous Allergens by Athauda Arachchi, P. M., Yahampath, N., Rajapakse, S.

“…Acute coronary syndromes, such as coronary spasm or acute myocardial infarction, have been reported following allergic reactions.  These are known to affect…”
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The impact of propranolol on nitric oxide and total antioxidant capacity in patients with resistant hypertension-evidence from the APPROPRIATE trial by Ranasinghe, H N, Fernando, N, Handunnetti, S, Weeratunga, P N, Katulanda, P, Rajapakse, S, Galappatthy, P, Constantine, G R

“…The objective was to assess the effect of propranolol on oxidative stress and anti-oxidant potential in patients with resistant hypertension as a secondary…”
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18F-Sodium Fluoride PET as a Diagnostic Modality for Metabolic, Autoimmune, and Osteogenic Bone Disorders: Cellular Mechanisms and Clinical Applications by Park, Peter Sang Uk, Raynor, William Y., Sun, Yusha, Werner, Thomas J., Rajapakse, Chamith S., Alavi, Abass

“…In a healthy body, homeostatic actions of osteoclasts and osteoblasts maintain the integrity of the skeletal system. When cellular activities of osteoclasts…”
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Unilateral Phrenic Nerve Palsy in Infants with Congenital Zika Syndrome by Rajapakse, Nipunie S, Ellsworth, Kevin, Liesman, Rachael M, Ho, Mai Lan, Henry, Nancy, Theel, Elitza S, Wallace, Adam, Alvino, Ana Catarina Ishigami, de Mello, Luisa Medeiros, Meneses, Jucille

“…This case series of right unilateral diaphragmatic paralysis suggests peripheral nervous system involvement. Since the first identification of neonatal…”
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The first reported case of co-infection of imported hepatitis E and Plasmodium falciparum malaria in Sri Lanka by Senarathne, S., Rajapakse, S., De Silva, H. J., Seneviratne, S., Chulasiri, P., Fernando, D.

“…Global travel and tourism, especially across tropical countries, may lead to importation of malaria and other infectious diseases into Sri Lanka. This case…”
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A meta‐analysis of magnesium for tetanus by Rodrigo, C., Samarakoon, L., Fernando, S. D., Rajapakse, S.

“…Summary Uncontrolled studies suggest that magnesium sulphate controls spasms in patients with established tetanus. We performed a meta‐analysis of controlled…”
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