Search Results - "Rajaniemi, Hannu"

Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures by Eroshenko, Nikolai, Gill, Taylor, Keaveney, Marianna K., Church, George M., Trevejo, Jose M., Rajaniemi, Hannu

Get full text

VAMP8/endobrevin as a general vesicular SNARE for regulated exocytosis of the exocrine system by Wang, Cheng-Chun, Shi, Hong, Guo, Ke, Ng, Chee Peng, Li, Jie, Gan, Bin Qi, Chien Liew, Hwee, Leinonen, Jukka, Rajaniemi, Hannu, Zhou, Zhi Hong, Zeng, Qi, Hong, Wanjin

“…The molecular mechanism governing the regulated secretion of most exocrine tissues remains elusive, although VAMP8/endobrevin has recently been shown to be the…”
Get full text

Identification and Structural Characterization of the Neuronal Luteinizing Hormone Receptor Associated with Sensory Systems by Apaja, Pirjo M., Harju, Kirsi T., Aatsinki, Jyrki T., Petäjä-Repo, Ulla E., Rajaniemi, Hannu J.

“…The luteinizing hormone receptor (LHR) is a G protein-coupled receptor involved in regulation of ovarian and testicular functions. Here we show that the…”
Get full text

Inefficient maturation of the rat luteinizing hormone receptor. A putative way to regulate receptor numbers at the cell surface by Pietilä, E Maritta, Tuusa, Jussi T, Apaja, Pirjo M, Aatsinki, Jyrki T, Hakalahti, Anna E, Rajaniemi, Hannu J, Petäjä-Repo, Ulla E

“…Increasing evidence suggests that the folding and maturation of monomeric proteins and assembly of multimeric protein complexes in the endoplasmic reticulum…”
Get full text

The Identification of Secreted Carbonic Anhydrase VI as a Constitutive Glycoprotein of Human and Rat Milk by Karhumaa, Pepe, Leinonen, Jukka, Parkkila, Seppo, Kaunisto, Kari, Tapanainen, Juha, Rajaniemi, Hannu

“…In addition to essential nutrients, human milk contains several classes of bioactive factors such as enzymes, hormones, and growth factors, many of which are…”
Get full text

Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum by Apaja, Pirjo M, Tuusa, Jussi T, Pietilä, E Maritta, Rajaniemi, Hannu J, Petäjä-Repo, Ulla E

“…The luteinizing hormone receptor (LHR) is a G protein-coupled receptor that is expressed in multiple RNA messenger forms. The common rat ectodomain splice…”
Get full text

Expression of Membrane-Associated Carbonic Anhydrase XIV on Neurons and Axons in Mouse and Human Brain by Parkkila, Seppo, Parkkila, Anna-Kaisa, Rajaniemi, Hannu, Shah, Gul N., Grubb, Jeffrey H., Waheed, Abdul, Sly, William S.

“…Although long suspected from histochemical evidence for carbonic anhydrase (CA) activity on neurons and observations that CA inhibitors enhance the…”
Get full text

Expression of the Mature Luteinizing Hormone Receptor in Rodent Urogenital and Adrenal Tissues Is Developmentally Regulated at a Posttranslational Level by Apaja, Pirjo M, Aatsinki, Jyrki T, Rajaniemi, Hannu J, Petäjä-Repo, Ulla E

“…The LH receptor (LHR) is a G protein-coupled receptor involved in the regulation of ovarian and testicular functions. In this study we demonstrate novel and…”
Get full text

Carbonic anhydrase XIV: Luminal expression suggests key role in renal acidification by Kaunisto, Kari, Parkkila, Seppo, Rajaniemi, Hannu, Waheed, Abdul, Grubb, Jeffrey, Sly, William S.

“…Carbonic anhydrase XIV: Luminal expression suggests key role in renal acidification. Carbonic anhydrase (CA) plays a fundamental role in regulation of systemic…”
Get full text

Expression of a Novel Transmembrane Carbonic Anhydrase Isozyme XII in Normal Human Gut and Colorectal Tumors by Kivelä, Antti, Parkkila, Seppo, Saarnio, Juha, Karttunen, Tuomo J., Kivelä, Jyrki, Parkkila, Anna-Kaisa, Waheed, Abdul, Sly, William S., Grubb, Jeffrey H., Shah, Gul, Türeci, Özlem, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII is a recently discovered member of the α-carbonic anhydrase gene family with a suggested role in von Hippel-Lindau gene-mediated…”
Get full text

Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa by Kivela, Antti-J, Parkkila, Seppo, Saarnio, Juha, Karttunen, Tuomo-J, Kivela, Jyrki, Parkkila, Anna-Kaisa, Bartosova, Maria, Mucha, Vojtech, Novak, Michal, Waheed, Abdul, Sly, William-S, Rajaniemi, Hannu, Pastorekova, Silvia, Pastorek, Jaromir

“…To analyze possible relationships between CA IX/CA XII and pVHL expression in normal and neoplastic colorectal mucosa. Immunohistochemical staining of 42…”
Get full text

Salivary carbonic anhydrase isoenzyme VI by Kivelä, Jyrki, Parkkila, Seppo, Parkkila, Anna‐Kaisa, Leinonen, Jukka, Rajaniemi, Hannu

“…The carbonic anhydrases (CAs) participate in the maintenance of pH homeostasis in various tissues and biological fluids of the human body by catalysing the…”
Get full text

Expression of the Membrane-associated Carbonic Anhydrase Isozyme XII in the Human Kidney and Renal Tumors by Parkkila, Seppo, Parkkila, Anna-Kaisa, Saarnio, Juha, Kivela, Jyrki, Karttunen, Tuomo J, Kaunisto, Kari, Waheed, Abdul, Sly, William S, Tureci, Ozlem, Virtanen, Ismo, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII (CA XII) is a novel membrane-associated protein with a potential role in von Hippel–Lindau carcinogenesis. Although Northern…”
Get full text

Localization of Carbonic Anhydrase XII to the Basolateral Membrane of H+-secreting Cells of Mouse and Rat Kidney by Kyllonen, Matti S, Parkkila, Seppo, Rajaniemi, Hannu, Waheed, Abdul, Grubb, Jeffrey H, Shah, Gul N, Sly, William S, Kaunisto, Kari

“…Membrane-associated carbonic anhydrase (CA) has a crucial role in renal HCO3 − absorption. CA activity has been localized to both luminal and basolateral…”
Get full text

Immunohistochemical Demonstration of Carbonic Anhydrase Isoenzyme VI (CA VI) Expression in Rat Lower Airways and Lung by Leinonen, Jukka S, Saari, Kirsi A, Seppanen, Jaana M, Myllyla, Hanna M, Rajaniemi, Hannu J

“…Carbonic anhydrase isoenzyme VI (CA VI), which is transported in high concentrations in saliva and milk into the alimentary tract, is an important element of…”
Get full text

Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours by Kivelä, A J, Parkkila, S, Saarnio, J, Karttunen, T J, Kivelä, J, Parkkila, A K, Pastoreková, S, Pastorek, J, Waheed, A, Sly, W S, Rajaniemi, H

“…Carbonic anhydrase (CA) IX and XII are transmembrane isoenzymes which are expressed in several epithelia and overexpressed in some carcinomas. They have…”
Get full text

The Expression of Carbonic Anhydrase II in Hematological Malignancies by Leppilampi, Mari, Koistinen, Pirjo, Savolainen, Eeva-Riitta, Hannuksela, Jokke, Parkkila, Anna-Kaisa, Niemelä, Onni, Pastoreková, Silvia, Pastorek, Jaromir, Waheed, Abdul, Sly, William S, Parkkila, Seppo, Rajaniemi, Hannu

“…Purpose: Carbonic anhydrases (CAs) are key enzymes that regulate acid-base homeostasis in both normal and pathological conditions. Recent studies have shown…”
Get full text

Secretion of Carbonic Anhydrase Isoenzyme VI (CA VI) from Human and Rat Lingual Serous von Ebner's Glands by Leinonen, Jukka, Parkkila, Seppo, Kaunisto, Kari, Koivunen, Petri, Rajaniemi, Hannu

“…Salivary carbonic anhydrase VI (CA VI) appears to contribute to taste function by protecting taste receptor cells (TRCs) from apoptosis. The serous von Ebner's…”
Get full text

An alternative use of basic pGEX vectors for producing both N- and C-terminal fusion proteins for production and affinity purification of antibodies by Aatsinki, Jyrki T., Rajaniemi, Hannu J.

“…Glutathione S-transferase (GST) fusion proteins are widely used in protein production for pure immunogens, protein–protein, and DNA–protein interaction…”
Get full text

Salivary carbonic anhydrase isoenzyme VI is located in the human enamel pellicle by Leinonen, J, Kivelä, J, Parkkila, S, Parkkila, A K, Rajaniemi, H

“…Salivary carbonic anhydrase (CA VI) appears to protect teeth from caries via mechanisms other than direct regulation of salivary pH and buffering capacity. To…”
Get more information