Search Results - "Rajani Malla"
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A Review on the Effect of Plant Extract on Mesenchymal Stem Cell Proliferation and Differentiation
Published in Stem cells international (2019)“…Stem cell has immense potential in regenerative cellular therapy. Mesenchymal stem cells (MSCs) can become a potential attractive candidate for therapy due to…”
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Pharmacokinetics and Pharmacodynamics of a Novel Virulent Klebsiella Phage Kp_Pokalde_002 in a Mouse Model
Published in Frontiers in cellular and infection microbiology (16-08-2021)“…Phage therapy is one of the most promising alternatives to antibiotics as we face global antibiotic resistance crisis. However, the pharmacokinetics (PK) and…”
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Maculosin, a non-toxic antioxidant compound isolated from Streptomyces sp. KTM18
Published in Pharmaceutical biology (01-01-2021)“…Streptomyces species are prolific sources of bioactive secondary metabolites known especially for their antimicrobial and anticancer activities. This study…”
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Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers
Published in BMC pharmacology & toxicology (04-05-2020)“…It is prudent that novel classes of antibiotics be urgently developed to manage the WHO prioritized multi-drug resistant (MDR) pathogens posing an…”
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Therapeutic Efficacy of Bacteriophage Therapy to Treat Carbapenem Resistant Klebsiella Pneumoniae in Mouse Model
Published in Journal of Nepal Health Research Council (23-04-2021)“…Global emergence of carbapenem-resistant Klebsiella pneumoniae is a major public health concern. Phage therapy - application of lytic phage to kill pathogenic…”
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Isolation and Characterization of Lytic Bacteriophage Against Multi-drug Resistant Pseudomonas aeruginosa
Published in Journal of Nepal Health Research Council (13-03-2022)“…Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen frequently causing healthcare-associated infections. The apocalyptic rise of antimicrobial…”
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Study on Phytochemical, Antibacterial, Antioxidant and Toxicity Profile of Viscum album Linn Associated with Acacia catechu
Published in Nepal journal of biotechnology (30-12-2015)“…This study focuses on antibacterial, antioxidant and toxic potentials of Viscum album Linn, commonly known as European mistletoe associated with Acacia catechu…”
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Isolation and Physicochemical Characterization of Laccase from Ganoderma lucidum-CDBT1 Isolated from Its Native Habitat in Nepal
Published in BioMed research international (01-01-2016)“…At present, few organisms are known to and capable of naturally producing laccases and white rot fungi are one such group. In the present study, three fungal…”
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Genomic characterization of three bacteriophages targeting multidrug resistant clinical isolates of Escherichia, Klebsiella and Salmonella
Published in Archives of microbiology (01-06-2022)“…Application of bacteriophages (phages) to treat complex multidrug-resistant bacterial infection is gaining traction because of its efficacy and universal…”
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Preclinical characterization and in silico safety assessment of three virulent bacteriophages targeting carbapenem-resistant uropathogenic Escherichia coli
Published in International microbiology (22-03-2024)“…Phage therapy has recently been revitalized in the West with many successful applications against multi-drug-resistant bacterial infections. However, the lack…”
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Complete Genome Sequence of Myophage Ec_Makalu_002, Which Infects Uropathogenic Escherichia coli
Published in Microbiology resource announcements (30-01-2020)“…We isolated phage Ec_Makalu_002, which infects uropathogenic strains of Here, we report its complete genome sequence, annotated features, and relatedness to…”
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Re-emergence of dengue virus serotype 2 strains in the 2013 outbreak in Nepal
Published in Indian journal of medical research (New Delhi, India : 1994) (01-12-2015)“…Epidemiological interventions and mosquito control are the available measures for dengue control. The former approach uses serotype and genetic information on…”
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Emergence of dengue in Nepal
Published in Virusdisease (01-06-2018)“…Dengue virus is a major health problem in Nepal. The endogenous dengue appeared in 2006 in the country with reported outbreaks in 2010, 2013 and 2016. Eleven…”
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Isolation and molecular characterization of lactobacilli from traditional fermented Dahi produced at different altitudes in Nepal
Published in Dairy science & technology (2014)“…Dairy products are an important part of daily food in the Himalayan country of Nepal. A wide variety of traditional fermented milk products are obtained in…”
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Discrimination of Quality and Geographical Origin of Extra Virgin Olive Oil by S3 Device with Metal Oxides Gas Sensors
Published in Proceedings (01-11-2018)“…In the present work, a gas sensor device S3 based on an array of eight metal oxides semiconductor gas sensors has been demonstrated and applied to the…”
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Molecular studies of E. coli mercuric reductase gene (merA) and its impact on human health
Published in Nepal Medical College journal : NMCJ (01-09-2007)“…Bacterial plasmids encode resistance systems for toxic metal ions including Hg2+ functioning by energy-dependent efflux of toxic ions. The inducible mercury…”
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