Search Results - "Rajana, Nagaraju"

Development and Validation of Miglitol and Its Impurities by RP-HPLC and Characterization Using Mass Spectrometry Techniques by Balakumaran, Kesavan, Janagili, Mosesbabu, Rajana, Nagaraju, Papureddy, Sureshbabu, Anireddy, Jayashree

“…Alpha glucoside inhibitors used to treat type-2 diabetes mellitus (DM) are likely to be safe and effective. These agents are most effective for postprandial…”
Get full text

Identification, method development, validation, and characterization of Aza sugars by an ion-chromatography, high-resolution mass spectrometer, and LC-MS/MS by Rajana, Nagaraju, Madhavan, P., Moses Babu, J., b Deore, Balasaheb, Basavaiah, K., Devi, Dharamasoth Rama

“…Background Aza sugars are organi c sugars having nitrogen containing polyhydroxyl sugar molecules. These molecules are active pharmaceutical ingredients; these…”
Get full text

Novel cocrystals of brexpiprazole with improved solubility by Rama, Veeraswamy, Vidavulur, Siddaiah, Tadikonda, Pratap V., Rajana, Nagaraju, Mittapalli, Sudhir

“…[Display omitted] •Prepared novel cocrystals of brexpiprazole with biologically acceptable coformers.•All the cocrystals were completely characterized by PXRD,…”
Get full text

Formal synthesis of Cladospolide C &epi-Cladospolide C using R-(+)-γ-valerolactone as a chiral synthon by Datrika, Rajender, Kallam, Srinivasa Reddy, Vidavalur, Siddaiah, Rajana, Nagaraju, Pratap, T.V.

“…The formal synthesis of Cladospolide-C and its analog is achieved by using enantiopure (R)-γ–valerolactone 10. The significant points of this synthesis are the…”
Get full text

Characterization of Five Oxidative Degradation Impurities and One Process Impurity of Suvorexant Drug Substance by LC-MS/MS, HR-MS and 1D, 2D NMR: Validation of Suvorexant Drug Substance and Process Impurities by HPLC and UPLC by Rajana, Nagaraju, Devi, Dharamasoth Rama, Kumar Reddy, Dinne Naresh, Babu, J Moses, Basavaiah, K, Balakumaran, K

“…Abstract During the oxidative (10% H2O2) degradation of suvorexant drug substance, around 1.0% of one impurity and less than 1.0% four impurities were found by…”
Get full text

Inside Front Cover: Reversed‐phase chiral high‐performance liquid chromatography method for separation of abacavir sulfate enantiomer in drug substance by Ramesh, Ch, Rama devi, Dharmasoth, Srinivas, MNB, Rajana, Nagaraju, Krishna, S. Radha, Basavaiah, K.

“…DOI: 10.1002/sscp.202000080 The cover picture shows the development, optimization and validation of Reversed phase chiral HPLC method for separation of…”
Get full text

An Orthogonal Approach for Determination of Acetamide Content in Pharmaceutical Drug Substance and Base-Contaminated Acetonitrile by GC and GC-MS External Method by Rajana, Nagaraju, Yarbagi, Kaviaraj M, Balakumaran, K, Madhubabu, M V, Mosesbabu, J, Basavaiah, K, Rama Devi, Dharamasoth

“…Acetamide is a potential genotoxic impurity; it should control in drug substance based on daily dosage level. It forms from base-contaminated acetonitrile and…”
Get full text

A short diastereoselective synthesis of cis-(2S,4S) and cis-(2R,4R)-4-hydroxyprolines by Gajare, Vikas S., Khobare, Sandip R., Malavika, B., Rajana, Nagaraju, Venkateswara Rao, B., Syam Kumar, U.K.

“…[Display omitted] A concise synthesis of (2R,4R)-4-hydroxyproline (1) and (2S,4S)-4-hydroxyproline (2) has been developed in enantiomerically pure form from…”
Get full text

Back Cover: Development and validation of HPLC methodology for quantitative estimation of Efinaconazole in topical pharmaceutical formulation prepared in‐house for the treatment of onychomycosis by Rajana, Nagaraju, Ramana, D.V., Ganta, Rama Rao, Devi, Dharamasoth Rama, Deshpande, Amol A., Babu, J. Moses, Basavaiah, K.

“…DOI: 10.1002/sscp.202000050 The cover picture shows an orthogonal approach for method development and validation of three potential halo alkyl alcohol…”
Get full text

An orthogonal approach for method development and validation of three potential halo alkyl alcohol genotoxic impurities in miglitol drug substance by fast gas chromatography–mass spectrometry by Rajana, Nagaraju, Ramana, D.V., Ganta, Rama Rao, Devi, Dharamasoth Rama, Deshpande, Amol A., Babu, J. Moses, Basavaiah, K.

“…Miglitol is an azasugar. It is the oral antidiabetic drug that inhibits the glucose generation from the polysaccharides and oligosaccharides. The miglitol…”
Get full text

Reversed‐phase chiral high‐performance liquid chromatography method for separation of abacavir sulfate enantiomer in drug substance by Ramesh, Ch, Rama devi, Dharmasoth, Srinivas, MNB, Rajana, Nagaraju, Krishna, S. Radha, Basavaiah, K.

“…For separation of abacavir sulfate enantiomers, normal phase chiral methods were reported. Handling of normal phase solvents for high‐performance liquid…”
Get full text

Diversity oriented concise asymmetric synthesis of azasugars: a facile access to l-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine by Gajare, Vikas S., Khobare, Sandip R., Datrika, Rajender, Reddy, K. Srinivas, Rajana, Nagaraju, Kumar, Sarvesh, Venkateswara Rao, B., Syam Kumar, U.K.

“…[Display omitted] Diversity oriented concise asymmetric syntheses of l-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine have been…”
Get full text

Concise and highly stereoselective syntheses of d-fagomine and 2-epi-fagomine by Kallam, Srinivasa Reddy, Datrika, Rajender, Khobare, Sandip R., Gajare, Vikas S., Rajana, Nagaraju, Mohan, H. Rama, Babu, J. Moses, Siddaiah, V., Pratap, T.V.

“…[Display omitted] Highly stereoselective total syntheses of polyhydroxylated piperidines d-fagomine and 2-epi-fagomine have been developed starting from…”
Get full text

Quantitative method for determination of 3,3‐dimethylallyl bromide genotoxic impurity in Tazarotene drug substance by GC‐MS by Rajana, Nagaraju, Ramana, D.V, Moses Babu, J., Basavaiah, K., Rama Devi, Dharamasoth

“…A highly sensitive gas chromatography‐mass spectrometry quantitative method was developed for 3,3‐dimethylallyl bromide genotoxic impurity in the tazarotene…”
Get full text

Diastereoselective total synthesis of piperidine alkaloids: (2R,5R)-5-hydroxyhomopipecolic acid and (2R,5R,8R)-5-hydroxysedamine by Khobare, Sandip R., Gajare, Vikas S., Rajana, Nagaraju, Datrika, Rajender, Srinivasa Reddy, K., Syam Kumar, U.K., Siddaiah, Vidavalur

“…[Display omitted] Total synthesis of 2,5-disubstituted piperidine alkaloids, 5-hydroxyhomopipecolic acid (1) and 5-hydroxysedamine (2) was accomplished in…”
Get full text

A concise stereoselective synthesis of (+)-1-deoxy-6-epi-castanospermine by Gajare, Vikas S., Khobare, Sandip R., Datrika, Rajender, Reddy, K. Srinivasa, Rajana, Nagaraju, Babu, B. Kishore, Rao, B. Venkateswara, Syam Kumar, U.K.

“…[Display omitted] •The stereoselective imine reduction was achieved by using sodium cyanoborohydride.•Mitsunobu cyclization selectively with primary…”
Get full text