Search Results - "Rajan, Arathi"

Highly sensitive and quantitative HiBiT-tagged Nipah virus-like particles: A platform for rapid antibody neutralization studies by Rajan, Arathi, Nair, Anuja S., Pillai, Vinod Soman, Kumar, Binod, Pai, Anupama R., Benny, Bimitha, Veettil, Mohanan Valiya

“…Biocontainment regulations restrict the research on NiV to BSL-4 laboratories, thus limiting the mechanistic studies related to viral entry and allied…”
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Direct DNA binding by BRCA1 on β-hCG promoter and its clinical implications by Krishnan, Neethu, R L, Neetha, Warrier, Arathy V., Yadev, Induprabha, Anandan, Jaimie, Sundaram, Sankar, Rajan, Arathi, Kumari, Prianka, Ittycheria, Shreya Sara, V.G, Manasa, Mohammed, Serbin, S, Preethamol, Nair, Rakesh Sathish, Srinivas, Priya

“…The role of β-hCG in breast cancer is largely unknown, this study aims to analyse the gene expression and clinical implications of β-hCG and its isoforms in…”
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Partial genome analysis of cox1 subunit-I region in mitochondrial dna of canine mammary tumours by Krithiga, K., Rajan, Arathi, Rose Varghese, Geetu, Neetha, R.L., Patra, Dipyaman, Krishnan, Neethu, Warrier, Arathy, Sriniva, Priya

“…Oncogenesis is an area which continuously elicits research interest. There are innumerable factors which contribute to oncogenesis of which mitochondrial DNA…”
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Abstract 3384: ER-α: The paramount facet predisposing BRCA1 defective tumors by Rajan, Arathi, Latha, Neetha Rajan, Srinivas, Priya

“…Abstract BRCA1 and BRCA2 are key tumor-suppressor proteins that aid in DNA damage repair and hence, play a pivotal role in ensuring the cellular genomic…”
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Perspectives on mechanistic implications of ROS inducers for targeting viral infections by Nadhan, Revathy, Patra, Dipyaman, Krishnan, Neethu, Rajan, Arathi, Gopala, Srinivas, Ravi, Dashnamoorthy, Srinivas, Priya

“…In this perspective, we propose to leverage reactive oxygen species (ROS) induction as a potential therapeutic measure against viral infections. Our rationale…”
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Pregnancy Hormone Mediated Tumorigenesis in BRCA1 Defective Breast Cancers by Krishnan, Neethu, Yadev, Induprabha, Anandan, Jaimie, Patra, Dipyaman, Rajan, Arathi, Srinivas, Priya

“…Background and Objective BRCA1 mutations predispose to breast and ovarian cancers, the exact reason for the tissue specificity is unknown. The role of hormonal…”
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Deregulated estrogen receptor signaling and DNA damage response in breast tumorigenesis by Rajan, Arathi, Nadhan, Revathy, Latha, Neetha Rajan, Krishnan, Neethu, Warrier, Arathy V., Srinivas, Priya

“…Carriers of BRCA1 mutations have a higher chance of developing cancers in hormone-responsive tissues like the breast, ovary and prostate, compared to other…”
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Gene expression signatures: A tool for analysis of breast cancer prognosis and therapy by Latha, Neetha Rajan, Rajan, Arathi, Nadhan, Revathy, Achyutuni, Sarada, Sengodan, Satheesh Kumar, Hemalatha, Sreelatha Krishnakumar, Varghese, Geetu Rose, Thankappan, Ratheeshkumar, Krishnan, Neethu, Patra, Dipyaman, Warrier, Arathy, Srinivas, Priya

“…[Display omitted] Breast Cancer is the most predominant female cancer in developed as well as developing countries. The treatment strategies of breast cancers…”
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βhCG mediates immune suppression through upregulation of CD11b+Gr1+ myeloid derived suppressor cells, CD206+ M2 macrophages, and CD4+FOXP3+ regulatory T‐cells in BRCA1 deficient breast cancers by Varghese, Geetu Rose, Patra, Dipyaman, Jaikumar, Vishnu Sunil, Rajan, Arathi, Latha, Neetha R., Srinivas, Priya

“…BRCA1 mutation is reported in about 70% of all triple negative breast cancers (TNBC), while BRCA1 defect due to promoter hypermethylation is seen in about…”
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Proteomic Profiling of β‑hCG-Induced Spheres in BRCA1 Defective Triple Negative Breast Cancer Cells by Sengodan, Satheesh Kumar, Rajan, Arathi, Hemalatha, Sreelatha Krishnakumar, Nadhan, Revathy, Jaleel, Abdul, Srinivas, Priya

“…Previously, we identified that β-hCG is expressed by BRCA1 mutated but not wild type breast cancers in vitro/in vivo and exhibited a novel event in β-hCG…”
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Mast cells as prognostic indicator in spontaneous canine mammary carcinomas by Krithiga, K., Rajan, Arathi, Varghese, Geetu Rose, Neetha, R. L., Krishnan, Neethu, Patra, Dipyaman, Warrier, Arathy V., Srinivas, Priya

“…Tumour micro-environment is essential to nourish the cancer stem cells (CSC) which are said to be the major cause to initiate recurrence/ metastasis. Though…”
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Brcal Defective Breast Cancer Cells Induce in vitro Transformation of Cancer Associated Fibroblasts (CAFs) to Metastasis Associated Fibroblasts (MAF) by Hemalatha, Sreelatha K., Sengodan, Satheesh Kumar, Nadhan, Revathy, Dev, Jithin, Sushama, Reshma R., Somasundaram, Veena, Thankappan, Ratheeshkumar, Rajan, Arathi, Latha, Neetha Rajan, Varghese, Geetu Rose, Mathew, Arun Peter, Somanathan, Thara, Srinivas, Priya

“…It is known that Cancer Associated Fibroblast (CAFs) from the primary tumor site can accompany cancer cells to a secondary site during the process of…”
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Insights into dovetailing GTD and Cancers by Nadhan, Revathy, Vaman, Jayashree V, C, Nirmala, Kumar Sengodan, Satheesh, Krishnakumar Hemalatha, Sreelatha, Rajan, Arathi, Varghese, Geetu Rose, RL, Neetha, BV, Amritha Krishna, Thankappan, Ratheeshkumar, Srinivas, Priya

“…Abstract Gestational trophoblastic diseases (GTD) encompass a group of placental tumors which mostly arise due to certain fertilization defects, resulting in…”
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BRCA1 promoter hypermethylation in human placenta: A hidden link with β-hCG expression by Nadhan, Revathy, Vaman, Jayashree V, Sengodan, Satheesh Kumar, Hemalatha, Sreelatha K, Nirmala, C, Sadasivan, Santha, Aysha, P V, Yesodharan, Sreelekha, Krishnapriya, R S, Amritha Krishna, B V, P S, Sreevidya, Rajan, Arathi, Rajan Latha, Neetha, Varghese, Geetu Rose, Thankappan, Ratheeshkumar, Achyutuni, Sarada, Jithin, Dev S U, Anil Kumar, T V, Srinivas, Priya

“…Gestational Trophoblastic Diseases (GTD) is group of pregnancy related tumors characterized by abnormal levels of "β-hCG" with higher incidence in South-East…”
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Modulation of BRCA1 mediated DNA damage repair by deregulated ER-α signaling in breast cancers by Rajan, Arathi, Varghese, Geetu R, Yadev, Induprabha, Anandan, Jaimie, Latha, Neetha R, Patra, Dipyaman, Krishnan, Neethu, Kuppusamy, Krithiga, Warrier, Arathy V, Bhushan, Satej, Nadhan, Revathy, Ram Kumar, Ram Mohan, Srinivas, Priya

“…BRCA1 mutation carriers have a greater risk of developing cancers in hormone-responsive tissues like breasts and ovaries. However, this tissue-specific…”
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Implementation of AES Algorithm on Text And Image using MATLAB by Aparna, V S, Rajan, Arathi, Jairaj, Indu, Nandita, B, Madhusoodanan, Parvathy, Remya, Ajai A S

“…One of the major problems faced by the world today is Data Security. In reality communication channel which is used to transfer data from transmitter to…”
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Range extension and molecular taxonomy of Propeamussium arabicum (Mollusca: Bivalvia: Propeamussiidae) from Indian waters by Arathi, Anitha Rajan, Ravinesh, Raveendhiran, Dhaneesh, Kottila Veettil, Bijukumar, Appukuttannair

“…The thin shelled pectinoidean bivalve, Propeamussium arabicum is a molluscan species originally described from Gulf of Aden. This paper records the first…”
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