Search Results - "Rajaiah Prabhu, Prince"

Initiation and modulation of Tau protein phase separation by the drug suramin by Prince, Prabhu Rajaiah, Hochmair, Janine, Brognaro, Hévila, Gevorgyan, Susanna, Franck, Maximilian, Schubert, Robin, Lorenzen, Kristina, Yazici, Selin, Mandelkow, Eckhard, Wegmann, Susanne, Betzel, Christian

“…Tau is an intrinsically disordered neuronal protein in the central nervous system. Aggregated Tau is the main component of neurofibrillary tangles observed in…”
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Construction and validation of a multi-epitope in silico vaccine model for lymphatic filariasis by targeting Brugia malayi: a reverse vaccinology approach by Madanagopal, Premnath, Muthusamy, Sathya, Pradhan, Satya Narayan, Prince, Prabhu Rajaiah

“…Background Lymphatic filariasis (LF), often referred to as elephantiasis, has been identified as one of the 17 neglected tropical diseases by the World Health…”
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Immunoadjuvant effect of diethylcarbamazine in experimental filariasis by Parasurama Jawaharlal, Jeya Prita, Rajaiah Prabhu, Prince, Gandhirajan, Anugraha, Krishnan, Nithya, Perumal, Kaliraj

“…Lymphatic filariasis caused by tissue dwelling nematodes is endemic in 73 countries and drugs have been administered to control or stop the infection…”
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Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic filariasis by Madhumathi, Jayaprakasam, Prince, Prabhu Rajaiah, Anugraha, Gandhirajan, Kiran, Pote, Rao, Donthamsetty Nageswara, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Abstract Although multi-epitope vaccines have been evaluated for various diseases, they have not yet been investigated for lymphatic filariasis. Here, we…”
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Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide29―43 in an endemic population of human lymphatic filariasis by MADHUMATHI, Jayaprakasam, ANUGRAHA, Gandhirajan, RAJAIAH PRINCE, Prabhu, PRADIBA, Dhinakar, KALIRAJ, Perumal

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Comparison of immunogenicity, protective efficacy of single and cocktail DNA vaccine of Brugia malayi abundant larval transcript (ALT-2) and thioredoxin peroxidase (TPX) in mice by Anand, Setty Balakrishnan, Murugan, Vadivel, Prabhu, Prince Rajaiah, Anandharaman, Veerabhadran, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Although DNA vaccines have several advantages over conventional vaccines, antibody production and protection are often not adequate, particularly in single…”
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Identification of a Highly Immunoreactive Epitope of Brugia malayi TPx Recognized by the Endemic Sera by Madhumathi, Jayaprakasam, Prince, Prabhu Rajaiah, Gayatri, Subash Chellam, Aparnaa, Ramanathan, Kaliraj, Perumal

“…Filarial thiordoxin peroxidase is a major antioxidant that plays a crucial role in parasite survival. Although Brugia malayi TPx has been shown to be a…”
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Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis by Rajaiah Prabhu, Prince, Moorthy, Sakthi Devi, Madhumathi, Jayaprakasam, Pradhan, Satya Narayan, Perbandt, Markus, Betzel, Christian, Kaliraj, Perumal

“…The notoriety of parasitic nematode survival is directly related to chronic pathogenicity, which is evident in human lymphatic filariasis. It is a disease of…”
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Protective immune responses of recombinant VP2 subunit antigen of infectious bursal disease virus in chickens by Pradhan, Satya Narayan, Prince, Prabhu Rajaiah, Madhumathi, Jayaprakasam, Roy, Parimal, Narayanan, Rangarajan Badri, Antony, Usha

“…Infectious bursal disease virus (IBDV) is the causative agent of Gumboro disease and poses a huge threat to poultry industry. The risks associated with…”
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DNA vaccination with VP2 gene fragment confers protection against Infectious Bursal Disease Virus in Chickens by Pradhan, Satya Narayan, Prince, Prabhu Rajaiah, Madhumathi, Jayaprakasam, Arunkumar, Chakkaravarthy, Roy, Parimal, Narayanan, Rangarajan Badri, Antony, Usha

“…Infectious Bursal Disease Virus (IBDV) causes immunosuppression in young chickens by destruction of antibody producing B cells in the Bursa of Fabricius and…”
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Functional analysis of genetic polymorphism in Wuchereria bancrofti glutathione S-transferase antioxidant gene: Impact on protein structure and enzyme catalysis by Sakthidevi, Moorthy, Prabhu, Prince Rajaiah, Chowdhary, Swati, Hoti, Sugeerappa Laxmanappa, Kaliraj, Perumal

“…The identified Wb-GST variant proteins exhibited altered kinetics for inhibitors and enhanced catalytic activity for lipid peroxidation products which might…”
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Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide(29-43) in an endemic population of human lymphatic filariasis by Madhumathi, Jayaprakasam, Anugraha, Gandhirajan, Prince, Prabhu Rajaiah, Pradiba, Dhinakar, Kaliraj, Perumal

“…Although the antioxidant thioredoxin peroxidase (TPX) is a putative target exploited in vaccine studies of lymphatic filariasis, the high sequence homology…”
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Proliferative responses of Brugia malayi TPX-1 and its epitopic peptide 29–43 in an endemic population of human lymphatic filariasis by Madhumathi, Jayaprakasam, Anugraha, Gandhirajan, Prince, Prabhu Rajaiah, Pradiba, Dhinakar, Kaliraj, Perumal

“…Although the antioxidant thioredoxin peroxidase (TPX) is a putative target exploited in vaccine studies of lymphatic filariasis, the high sequence homology…”
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Repeat region of Brugia malayi sheath protein (Shp-1) carries Dominant B epitopes recognized in filarial endemic population by Jawaharlal, Jeya Prita Parasurama, Madhumathi, Jayaprakasam, Prince, Rajaiah Prabhu, Kaliraj, Perumal

“…Transmission of lymphatic filariasis is mediated through microfilariae (L1 stage of the parasite) which is encased in an eggshell called sheath. The sheath…”
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Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions by Girelli, Anita, Bin, Maddalena, Filianina, Mariia, Dargasz, Michelle, Anthuparambil, Nimmi Das, Möller, Johannes, Zozulya, Alexey, Andronis, Iason, Timmermann, Sonja, Berkowicz, Sharon, Retzbach, Sebastian, Reiser, Mario, Raza, Agha Mohammad, Kowalski, Marvin, Akhundzadeh, Mohammad Sayed, Schrage, Jenny, Woo, Chang Hee, Senft, Maximilian D, Reichart, Lara Franziska, Leonau, Aliaksandr, Rajaiah, Prince Prabhu, Chèvremont, William, Seydel, Tilo, Hallmann, Jörg, Rodriguez-Fernandez, Angel, Pudell, Jan-Etienne, Brausse, Felix, Boesenberg, Ulrike, Wrigley, James, Youssef, Mohamed, Lu, Wei, Jo, Wonhyuk, Shayduk, Roman, Madsen, Anders, Lehmkühler, Felix, Paulus, Michael, Zhang, Fajun, Schreiber, Frank, Gutt, Christian, Perakis, Fivos

“…Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how…”
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