Search Results - "Rajagopalan, Lakshmi"
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De novo assembly and annotation of the CHOZN® GS−/− genome supports high‐throughput genome‐scale screening
Published in Biotechnology and bioengineering (01-12-2022)“…Chinese hamster ovary (CHO) cells have been used as the industry standard for the production of therapeutic monoclonal antibodies for several decades. Despite…”
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Relation between macular retinal ganglion cell/inner plexiform layer thickness and multifocal electroretinogram measures in experimental glaucoma
Published in Investigative ophthalmology & visual science (26-06-2014)“…We investigated relations between macular retinal ganglion cell plus inner plexiform layer (RGC+IPL) thickness and macular retinal function revealed by…”
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In Vivo Changes in Lamina Cribrosa Microarchitecture and Optic Nerve Head Structure in Early Experimental Glaucoma
Published in PloS one (31-07-2015)“…The lamina cribrosa likely plays an important role in retinal ganglion cell axon injury in glaucoma. We sought to (1) better understand optic nerve head (ONH)…”
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Stratifying low level Isoniazid resistance using additional intermediate drug concentration
Published in International journal of mycobacteriology (01-06-2014)“…Abstract Isoniazid (INH) susceptibility testing for 100 Mycobacterium tuberculosis performed by conventional minimum inhibitory concentration (MIC) method was…”
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Optimization of the conventional minimum inhibitory concentration method for drug susceptibility testing of ethionamide
Published in International journal of mycobacteriology (01-03-2013)“…Abstract Evaluation of newer methods and optimization of existing methods for the susceptibility testing of second-line drugs, especially ethionamide, are…”
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Using a Novel, Subconjunctival, Sustained-Release Mitomycin C Formulation in a Rabbit Model of Filtration Surgery with Gel Stent Implantation
Published in Journal of ocular pharmacology and therapeutics (01-06-2024)“…To investigate gel stent implantation with and without intraoperative sustained-release mitomycin C (MMC SR) in a rabbit model for gel stent implantation, and…”
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Intraocular Pressure-Lowering Efficacy of a Sustained-Release Bimatoprost Implant in Dog Eyes Pretreated with Selective Laser Trabeculoplasty
Published in Journal of ocular pharmacology and therapeutics (01-05-2022)“…To assess the intraocular pressure (IOP)-lowering effect of a biodegradable bimatoprost implant following selective laser trabeculoplasty (SLT) in a canine…”
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A nonhuman primate model of blue light-induced progressive outer retina degeneration showing brimonidine drug delivery system-mediated cyto- and neuroprotection
Published in Experimental eye research (01-08-2021)“…Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterized by atrophy of the retinal pigment epithelium (RPE), loss of…”
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Evaluating Health Impacts from a Bus Rapid Transit System Implementation in India: Case Study of Indore, Madhya Pradesh
Published in Transportation research record (01-01-2015)“…Sustainable transportation interventions affect public health in three ways: through (a) reduced pollution emissions, (b) increased physical activity, and (c)…”
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Long-term blue light rearing does not affect in vivo retinal function in young rhesus monkeys
Published in Documenta ophthalmologica (01-08-2023)“…Purpose Exposure to blue light is thought to be harmful to the retina. The purpose of this study was to determine the effects of long-term exposure to…”
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A preclinical study of the intraocular pressure lowering efficacy of bimatoprost sustained release in eyes pretreated with selective laser trabeculoplasty
Published in Acta ophthalmologica (Oxford, England) (01-12-2019)“…Purpose Selective Laser Trabeculoplasty (SLT) is a treatment for lowering intraocular pressure (IOP) in patients with glaucoma, however IOP‐lowering is not…”
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Revisiting the susceptibility testing of Mycobacterium tuberculosis to ethionamide in solid culture medium
Published in Indian journal of medical research (New Delhi, India : 1994) (01-11-2015)“…Increase in the isolation of drug resistant phenotypes of Mycobacterium tuberculosis necessitates accuracy in the testing methodology. Critical concentration…”
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Modification of proportion sensitivity testing method for ethionamide
Published in World journal of microbiology & biotechnology (01-06-2013)“…Standardized methodology for drug susceptibility testing of second line drugs is vital for treatment of multi/extensively drug resistant tuberculosis…”
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In Vivo Changes in Lamina Cribrosa Microarchitecture and Optic Nerve Head Structure in Early Experimental Glaucoma: e0134223
Published in PloS one (01-07-2015)“…The lamina cribrosa likely plays an important role in retinal ganglion cell axon injury in glaucoma. We sought to (1) better understand optic nerve head (ONH)…”
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SYSPART: Automated Temporal System Call Filtering for Binaries
Published 10-09-2023“…Restricting the system calls available to applications reduces the attack surface of the kernel and limits the functionality available to compromised…”
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Brief Communications-Occurrence of extended spectrum beta-lactamases among Enterobacteriaceae spp. isolated at a tertiary care institute
Published in Indian journal of medical microbiology (31-08-2006)“…Increasing resistance to third generation cephalosporins has become a cause for concern especially among Enterobacteriaceae that cause nosocomial infections…”
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