Search Results - "Rajagopala, Seesandra"

Salivary immunoinflammatory proteins identify children with eosinophilic esophagitis by Hiremath, Girish, Wang, Yu, Correa, Hernan, Sheng, Quanhu, Rajagopala, Seesandra V.

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The Human Microbiome and Cancer by Rajagopala, Seesandra V, Vashee, Sanjay, Oldfield, Lauren M, Suzuki, Yo, Venter, J Craig, Telenti, Amalio, Nelson, Karen E

“…Recent scientific advances have significantly contributed to our understanding of the complex connection between the microbiome and cancer. Our bodies are…”
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Persistent Gut Microbial Dysbiosis in Children with Acute Lymphoblastic Leukemia (ALL) During Chemotherapy by Rajagopala, Seesandra V., Singh, Harinder, Yu, Yanbao, Zabokrtsky, Keri B., Torralba, Manolito G., Moncera, Kelvin J., Frank, Bryan, Pieper, Rembert, Sender, Leonard, Nelson, Karen E.

“…Prophylactic or therapeutic antibiotic use along with chemotherapy treatment potentially has a long-standing adverse effect on the resident gut microbiota. We…”
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The protein interaction map of bacteriophage lambda by Rajagopala, Seesandra V, Casjens, Sherwood, Uetz, Peter

“…Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage…”
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The binary protein-protein interaction landscape of Escherichia coli by Rajagopala, Seesandra V, Sikorski, Patricia, Kumar, Ashwani, Mosca, Roberto, Vlasblom, James, Arnold, Roland, Franca-Koh, Jonathan, Pakala, Suman B, Phanse, Sadhna, Ceol, Arnaud, Häuser, Roman, Siszler, Gabriella, Wuchty, Stefan, Emili, Andrew, Babu, Mohan, Aloy, Patrick, Pieper, Rembert, Uetz, Peter

“…Yeast-two hybrid screening of E. coli proteins and integration with protein structure and genetic interaction data provides an extensive interactome resource…”
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SARS-CoV-2 infection and viral load are associated with the upper respiratory tract microbiome by Rosas-Salazar, Christian, Kimura, Kyle S., Shilts, Meghan H., Strickland, Britton A., Freeman, Michael H., Wessinger, Bronson C., Gupta, Veerain, Brown, Hunter M., Rajagopala, Seesandra V., Turner, Justin H., Das, Suman R.

“…Little is known about the relationships between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the respiratory virus responsible for the ongoing…”
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Children with eosinophilic esophagitis non‐responsive to combination therapy have distinct esophageal transcriptomic and microbiome profile by Hiremath, Girish, Choksi, Yash, Correa, Hernan, Jacobse, Justin, Das, Suman R., Ma, Siyuan, Goettel, Jeremy A., Rajagopala, Seesandra V.

“…Background A combination of proton‐pump inhibitors (PPI) and topical steroids (TS) is used to treat children with eosinophilic esophagitis (EoE). However, a…”
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Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats by Strickland, Britton A., Rajagopala, Seesandra V., Kamali, Arash, Shilts, Meghan H., Pakala, Suman B., Boukhvalova, Marina S., Yooseph, Shibu, Blanco, Jorge C. G., Das, Suman R.

“…The cotton rat ( Sigmodon ) is the gold standard pre-clinical small animal model for respiratory viral pathogens, especially for respiratory syncytial virus…”
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Mechanisms of action of Coxiella burnetii effectors inferred from host-pathogen protein interactions by Wallqvist, Anders, Wang, Hao, Zavaljevski, Nela, Memišević, Vesna, Kwon, Keehwan, Pieper, Rembert, Rajagopala, Seesandra V, Reifman, Jaques

“…Coxiella burnetii is an obligate Gram-negative intracellular pathogen and the etiological agent of Q fever. Successful infection requires a functional Type IV…”
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Evolutionarily conserved herpesviral protein interaction networks by Fossum, Even, Friedel, Caroline C, Rajagopala, Seesandra V, Titz, Björn, Baiker, Armin, Schmidt, Tina, Kraus, Theo, Stellberger, Thorsten, Rutenberg, Christiane, Suthram, Silpa, Bandyopadhyay, Sourav, Rose, Dietlind, von Brunn, Albrecht, Uhlmann, Mareike, Zeretzke, Christine, Dong, Yu-An, Boulet, Hélène, Koegl, Manfred, Bailer, Susanne M, Koszinowski, Ulrich, Ideker, Trey, Uetz, Peter, Zimmer, Ralf, Haas, Jürgen

“…Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes…”
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Gastrointestinal microbial populations can distinguish pediatric and adolescent Acute Lymphoblastic Leukemia (ALL) at the time of disease diagnosis by Rajagopala, Seesandra V, Yooseph, Shibu, Harkins, Derek M, Moncera, Kelvin J, Zabokrtsky, Keri B, Torralba, Manolito G, Tovchigrechko, Andrey, Highlander, Sarah K, Pieper, Rembert, Sender, Leonard, Nelson, Karen E

“…An estimated 15,000 children and adolescents under the age of 19 years are diagnosed with leukemia, lymphoma and other tumors in the USA every year. All…”
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S1473 Presidential Poster Award Metatranscriptomic Analysis of Pediatric Esophageal Epithelium and Microbiome Response to Proton-Pump Inhibitors by Rajagopala, Seesandra V., Shilts, Meghan H., Choksi, Yash, Das, Suman, Hiremath, Girish

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Mucosal Gene Expression in Response to SARS-CoV-2 Is Associated with Viral Load by Rajagopala, Seesandra V, Strickland, Britton A, Pakala, Suman B, Kimura, Kyle S, Shilts, Meghan H, Rosas-Salazar, Christian, Brown, Hunter M, Freeman, Michael H, Wessinger, Bronson C, Gupta, Veerain, Phillips, Elizabeth, Mallal, Simon A, Turner, Justin H, Das, Suman R

“…Little is known about the relationships between symptomatic early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load and upper airway…”
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Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms by Memišević, Vesna, Zavaljevski, Nela, Rajagopala, Seesandra V, Kwon, Keehwan, Pieper, Rembert, DeShazer, David, Reifman, Jaques, Wallqvist, Anders

“…Burkholderia pathogenicity relies on protein virulence factors to control and promote bacterial internalization, survival, and replication within eukaryotic…”
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Association between Oral Microbiome and Esophageal Diseases: A State-of-the-Art Review by Bernard, Rachel, Fazili, Irtiqa, Rajagopala, Seesandra V, Das, Suman R, Hiremath, Girish

“…Esophageal conditions result in significant morbidity and mortality worldwide. There is growing enthusiasm for discerning the role of microbiome in esophageal…”
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Enterovirus D-68 Infection, Prophylaxis, and Vaccination in a Novel Permissive Animal Model, the Cotton Rat (Sigmodon hispidus) by Patel, Mira C, Wang, Wei, Pletneva, Lioubov M, Rajagopala, Seesandra V, Tan, Yi, Hartert, Tina V, Boukhvalova, Marina S, Vogel, Stefanie N, Das, Suman R, Blanco, Jorge C G

“…In recent years, there has been a significant increase in detection of Enterovirus D-68 (EV-D68) among patients with severe respiratory infections worldwide…”
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The binary protein interactome of Treponema pallidum--the syphilis spirochete by Titz, Björn, Rajagopala, Seesandra V, Goll, Johannes, Häuser, Roman, McKevitt, Matthew T, Palzkill, Timothy, Uetz, Peter

“…Protein interaction networks shed light on the global organization of proteomes but can also place individual proteins into a functional context. If we know…”
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The Salivary Microbiome Is Altered in Children With Eosinophilic Esophagitis and Correlates With Disease Activity by Hiremath, Girish, Shilts, Meghan H, Boone, Helen H, Correa, Hernan, Acra, Sari, Tovchigrechko, Andrey, Rajagopala, Seesandra V, Das, Suman R

“…Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory disease affecting the esophagus. Although microbial communities may affect the host immune…”
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Mucosal Microbiome Disruption in Acute Laryngeal Injury Following Intubation by Davis, Ruth J., Shilts, Meghan H., Strickland, Britton A., Rajagopala, Seesandra V., Das, Suman R., Wootten, Christopher T., Gelbard, Alexander

“…The objective of this study was to characterize mucosal microbial shifts in patients with acute laryngeal injury (ALgI) after intubation. This cross‐sectional…”
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Intestinal epithelial cell-derived components regulate transcriptome of Lactobacillus rhamnosus GG by Schalich, Kasey, Rajagopala, Seesandra, Das, Suman, O'Connell, Ryan, Yan, Fang

“…Intestinal epithelial cells (IECs) provide the frontline responses to the gut microbiota for maintaining intestinal homeostasis. Our previous work revealed…”
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