Search Results - "Rajagopal, Krishnamoorthy"
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1
Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context
Published in Brain, behavior, and immunity (01-01-2021)“…•Major psychiatric disorders are associated with genetically-determined dysimmunity.•HLA molecules are prominent players of immune and neurodevelopmental…”
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2
Obsessive-Compulsive Disorder: Autoimmunity and Neuroinflammation
Published in Current psychiatry reports (01-08-2019)“…Purpose of Review Here, we propose to review the immuno-inflammatory hypothesis in OCD given the concurrent incidence of autoimmune comorbidities, infectious…”
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Synthesis and crystal growth of 2, 3-dimethyl-N-[2-(hydroxy) benzylidene] aniline: An organic second-order non-linear optical crystal for non-linear optical (NLO) applications
Published in Optical materials (01-03-2021)“…Optically transparent organic single crystal of 2,3-Dimethyl-N-[2-(hydroxy) benzylidene] aniline (DHBA) has been successfully prepared, and the single crystals…”
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4
Relationship between Toxoplasma gondii infection and bipolar disorder in a French sample
Published in Journal of affective disorders (01-06-2013)“…Abstract Background Prenatal exposure to viruses or parasites with tropism for the central nervous system is one of the risk factors for psychotic disorders…”
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5
Association between Parkinson's disease and the HLA-DRB1 locus
Published in Movement disorders (01-08-2012)“…Two genome‐wide association studies (GWASs) recently highlighted the HLA‐DRA and HLA‐DRB5 genes as associated with Parkinson disease (PD). However, because…”
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6
Combined effect of TLR2 gene polymorphism and early life stress on the age at onset of bipolar disorders
Published in PloS one (19-03-2015)“…Gene-environment interactions may play an important role in modulating the impact of early-life stressful events on the clinical course of bipolar disorder…”
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Correction: Dectin-1 Polymorphism: A Genetic Disease Specifier in Autism Spectrum Disorders?
Published in PloS one (14-03-2019)“…[This corrects the article DOI: 10.1371/journal.pone.0137339.]…”
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Persistence of dysfunctional natural killer cells in adults with high-functioning autism spectrum disorders: stigma/consequence of unresolved early infectious events?
Published in Molecular autism (15-05-2019)“…Autism spectrum disorders (ASD) are characterized by abnormal neurodevelopment, genetic, and environmental risk factors, as well as immune dysfunctions…”
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9
MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease
Published in Blood (10-12-2009)“…The MHC class I–related chain A (MICA) molecules exist as membrane-bound and soluble isoforms and are encoded by a polymorphic gene. Their genetic and…”
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10
Soluble MICA and anti-MICA Antibodies as Biomarkers of Nasopharyngeal Carcinoma Disease
Published in Immunological investigations (03-07-2020)“…The MHC class I chain-related molecule A (MICA) is a ligand for the activating natural killer (NK) cell receptor NKG2D. A part from its genetic diversity, MICA…”
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11
Dectin-1 Polymorphism: A Genetic Disease Specifier in Autism Spectrum Disorders?
Published in PloS one (09-09-2015)“…In autism spectrum disorders (ASD), complex gene-environment interactions contribute to disease onset and progress. Given that gastro-intestinal dysfunctions…”
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12
Immunoglobulin sub-class distribution in bipolar disorder and schizophrenia: potential relationship with latent Toxoplasma Gondii infection
Published in BMC psychiatry (27-07-2018)“…Immune dysfunction could play a significant role in the pathogenesis of bipolar disorder (BD) and schizophrenia (SZ), conditions with an underlying…”
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13
Association between toll-like receptor 2 gene diversity and early-onset bipolar disorder
Published in Journal of affective disorders (20-08-2014)“…Abstract Background Toll-like receptor 2 (TLR2) molecules play a pivotal role in innate immune responses by their ability to recognize and sense a wide…”
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14
The Association of CD81 Polymorphisms with Alloimmunization in Sickle Cell Disease
Published in Clinical & developmental immunology (01-01-2013)“…The goal of the present work was to identify the candidate genetic markers predictive of alloimmunization in sickle cell disease (SCD). Red blood cell (RBC)…”
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15
Warfarin pharmacogenetics: development of a dosing algorithm for Omani patients
Published in Journal of human genetics (01-10-2012)“…The objective of our present study was to develop a warfarin dosing algorithm for the Omani patients, as performances of warfarin dosing algorithms vary across…”
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16
C-Reactive Protein in Bipolar Disorder in an Indian Clinical Setting
Published in Journal of clinical and diagnostic research (01-09-2018)“…Introduction: Serious psychiatric illnesses like bipolar disorder lack specific biomarkers of diagnosis or prognosis. However, association between Bipolar…”
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17
IL6/IL6R genetic diversity and plasma IL6 levels in bipolar disorder: An Indo-French study
Published in Heliyon (01-01-2019)“…Reports of association of genetic variants of IL6 and its receptor (IL6R) with psychiatric disorders are inconsistent, and there are few population-based…”
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18
CYP2D6 Genetic Polymorphism in South Indian Populations
Published in Biological & Pharmaceutical Bulletin (01-08-2006)“…This study aimed to determine the prevalence of genetic polymorphism in the CYP2D6 gene, which codes for the polymorphically expressed CYP2D6 drug-metabolizing…”
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Association between CRP genetic diversity and bipolar disorder comorbid complications
Published in International Journal of Bipolar Disorders (20-01-2018)“…Background Chronic low-grade inflammation is believed to contribute, at least in a subset of patients, to the development of bipolar disorder (BD). In this…”
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CYP2C9 and CYP2C19 genetic polymorphisms: frequencies in the south Indian population
Published in Fundamental & clinical pharmacology (01-02-2005)“…The aim of the study was to establish the frequencies of CYP2C9*1, *2, *3 and CYP2C19*1, *2 and *3 in the south Indian population and to compare them with the…”
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