Search Results - "Raja, Erum"

Development and Evaluation of a Fluorescent Antibody-Drug Conjugate for Molecular Imaging and Targeted Therapy of Pancreatic Cancer by Knutson, Steve, Raja, Erum, Bomgarden, Ryan, Nlend, Marie, Chen, Aoshuang, Kalyanasundaram, Ramaswamy, Desai, Surbhi

“…Antibodies are widely available and cost-effective research tools in life science, and antibody conjugates are now extensively used for targeted therapy,…”
Get full text

DNA-Controlled Encapsulation of Small Molecules in Protein Nanoparticles by Ngo, Wayne, Stordy, Benjamin, Lazarovits, James, Raja, Erum K, Etienne, Chris L, Chan, Warren C. W

“…A nanoparticle can hold multiple types of therapeutic and imaging agents for disease treatment and diagnosis. However, controlling the storage of molecules in…”
Get full text

Fluoro-substituted ketones from nitriles using acidic and basic reaction conditions by Raja, Erum K., Klumpp, Douglas A.

“…Fluoro-substituted aliphatic nitriles are shown to undergo the Houben–Hoesch reactions with arenes in CF 3SO 3H to give fluoro-substituted ketones in good…”
Get full text

Friedel–Crafts Acylation with Amides by Raja, Erum K, DeSchepper, Daniel J, Nilsson Lill, Sten O, Klumpp, Douglas A

“…Friedel–Crafts acylation has been known since the 1870s, and it is an important organic synthetic reaction leading to aromatic ketone products. Friedel–Crafts…”
Get full text

Superacid-Promoted Additions Involving Vinyl-Substituted Pyrimidines, Quinoxalines, and Quinazolines: Mechanisms Correlated to Charge Distributions by Zhang, Yiliang, Sheets, Matthew R, Raja, Erum K, Boblak, Kenneth N, Klumpp, Douglas A

“…The superacid-promoted reactions of vinyl-substituted N-heterocycles have been studied. Diprotonated pyrimidines, quinoxalines, and quinazolines exhibit an…”
Get full text

Superelectrophilic chemistry of amino-nitriles and related substrates by Raja, Erum K., Klumpp, Douglas A.

“…The superacid-promoted Houben/Hoesch reactions of amino-nitriles and related compounds have been studied. The nitriles form dicationic electrophiles and react…”
Get full text

Preparation of Aryl-Susbstituted 2-Oxyindoles by Superelectrophilic Chemistry by Naredla, Rajasekhar Reddy, Raja, Erum K, Klumpp, Douglas A

“…A series of pyridyl-substituted 3-hydroxy-2-oxyindoles have been prepared and reacted with arenes in superacid promoted Friedel-Crafts reactions. The product…”
Get full text

Preparation of aryl-substituted 2-oxyindoles by superelectrophilic chemistry by Naredla, Rajasekhar Reddy, Raja, Erum K., Klumpp, Douglas A.

“…A series of pyridyl-substituted 3-hydroxy-2-oxyindoles have been prepared and reacted with arenes in superacid promoted Friedel–Crafts reactions. The product…”
Get full text

Abstract LB-001: Development and evaluation of a fluorescent antibody-drug conjugate for molecular imaging and targeted therapy of pancreatic cancer by Knutson, Steve, Raja, Erum, Bomgarden, Ryan, Nlend, Marie, Chen, Aoshuang, Kalyanasundaram, Ramaswamy, Desai, Surbhi

“…Developing new strategies to effectively diagnose and treat various types of cancer is paramount to increasing patient survival rates. Although…”
Get full text

Chemical reactions involving electrophiles and superelectrophiles by Raja, Erum Khalil

“…This dissertation describes two main areas of research. The first part deals with superacid-promoted Houben-Hoesch reactions of various amino-nitriles and…”
Get full text