Search Results - "Raj Dahal, Giri"
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Ion Channel Contributions to Wing Development in Drosophila melanogaster
Published in G3 : genes - genomes - genetics (01-04-2019)“…During morphogenesis, cells communicate with each other to shape tissues and organs. Several lines of recent evidence indicate that ion channels play a key…”
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Journal Article -
2
Purification of inclusion body-forming peptides and proteins in soluble form by fusion to Escherichia coli thermostable proteins
Published in BioTechniques (01-05-2008)“…Proteins and peptides expressed in the prokaryotic system often form inclusion bodies. Solubilization and refolding procedures can be used for their recovery,…”
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Journal Article -
3
Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling
Published in Nature communications (22-11-2017)“…The β 1 adrenergic receptor (β 1 AR) is recognized as a classical Gα s -coupled receptor. Agonist binding not only initiates G protein-mediated signaling but…”
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Journal Article -
4
An inwardly rectifying K+ channel is required for patterning
Published in Development (Cambridge) (01-10-2012)“…Mutations that disrupt function of the human inwardly rectifying potassium channel KIR2.1 are associated with the craniofacial and digital defects of…”
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Journal Article -
5
Both dimerization and interdomain processing are essential for caspase-4 activation
Published in Biochemical and biophysical research communications (18-05-2007)“…A subgroup of caspase family of inflammatory caspases (-1, -4, -5, -11, and -12) play important role during cytokine maturation and inflammation but their…”
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6
Inwardly rectifying potassium channels influence Drosophila wing morphogenesis by regulating Dpp release
Published in Development (Cambridge) (01-08-2017)“…Loss of embryonic ion channel function leads to morphological defects, but the underlying reason for these defects remains elusive. Here, we show that inwardly…”
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Journal Article -
7
Gα i is required for carvedilol-induced β 1 adrenergic receptor β-arrestin biased signaling
Published in Nature communications (22-11-2017)“…The β adrenergic receptor (β AR) is recognized as a classical Gα -coupled receptor. Agonist binding not only initiates G protein-mediated signaling but…”
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Journal Article -
8
Caspase-2 cleaves DNA fragmentation factor (DFF45)/Inhibitor of caspase-activated DNase (ICAD)
Published in Archives of biochemistry and biophysics (01-12-2007)“…To investigate the signal transduction pathway of caspase-2, cell permeable Tat–reverse-caspase-2 was constructed, characterized and utilized for biochemical…”
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Journal Article -
9
Developmental Signaling Requires Inwardly Rectifying K+ Channels in Drosophila melanogaster
Published 01-01-2013“…Inwardly rectifying potassium (IRK/Kir) channels regulate intracellular K+ concentrations and membrane potential. Disruption of Kir2.1 causes dominantly…”
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Dissertation -
10
Developmental Signaling Requires Inwardly Rectifying Potassium Channels in Drosophila melanogaster
Published 01-01-2013“…Inwardly rectifying potassium (IRK/Kir) channels regulate intracellular K+ concentrations and membrane potential. Disruption of Kir2.1 causes dominantly…”
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Dissertation -
11
Efficient cleavage of Bid and procaspase-7 by caspase-2 at lower pH
Published in Protein and peptide letters (01-10-2008)“…The activity of caspase-2 was examined under varying biochemical conditions with the synthetic and protein substrates, Bid and procaspase-7. The results…”
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