Search Results - "Raizada, Mohan"

The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease by Yang, Tao, Richards, Elaine M., Pepine, Carl J., Raizada, Mohan K.

“…Crosstalk between the gut microbiota and the host has attracted considerable attention owing to its involvement in diverse diseases. Chronic kidney disease…”
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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2 by Gheblawi, Mahmoud, Wang, Kaiming, Viveiros, Anissa, Nguyen, Quynh, Zhong, Jiu-Chang, Turner, Anthony J., Raizada, Mohan K., Grant, Maria B., Oudit, Gavin Y.

“…ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent functiona negative regulator of the…”
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Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure by Kim, Seungbum, Goel, Ruby, Kumar, Ashok, Qi, Yanfei, Lobaton, Gil, Hosaka, Koji, Mohammed, Mohammed, Handberg, Eileen M, Richards, Elaine M, Pepine, Carl J, Raizada, Mohan K

“…Recent evidence indicates a link between gut pathology and microbiome with hypertension (HTN) in animal models. However, whether this association exists in…”
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Gut Dysbiosis Is Linked to Hypertension by Yang, Tao, Santisteban, Monica M, Rodriguez, Vermali, Li, Eric, Ahmari, Niousha, Carvajal, Jessica Marulanda, Zadeh, Mojgan, Gong, Minghao, Qi, Yanfei, Zubcevic, Jasenka, Sahay, Bikash, Pepine, Carl J, Raizada, Mohan K, Mohamadzadeh, Mansour

“…Emerging evidence suggests that gut microbiota is critical in the maintenance of physiological homeostasis. This study was designed to test the hypothesis that…”
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Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression by Stevens, Bruce R, Goel, Ruby, Seungbum, Kim, Richards, Elaine M, Holbert, Richard C, Pepine, Carl J, Raizada, Mohan K

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Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension by Kim, Seungbum, Rigatto, Katya, Gazzana, Marcelo B., Knorst, Marli M., Richards, Elaine M., Pepine, Carl J., Raizada, Mohan K.

“…Pulmonary arterial hypertension (PAH) is considered a disease of the pulmonary vasculature. Limited progress has been made in preventing or arresting…”
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Hypertension-Linked Pathophysiological Alterations in the Gut by Santisteban, Monica M, Qi, Yanfei, Zubcevic, Jasenka, Kim, Seungbum, Yang, Tao, Shenoy, Vinayak, Cole-Jeffrey, Colleen T, Lobaton, Gilberto O, Stewart, Daniel C, Rubiano, Andres, Simmons, Chelsey S, Garcia-Pereira, Fernando, Johnson, Richard D, Pepine, Carl J, Raizada, Mohan K

“…RATIONALE:Sympathetic nervous system control of inflammation plays a central role in hypertension. The gut receives significant sympathetic innervation, is…”
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Gut Microbiome and Neuroinflammation in Hypertension by Richards, Elaine M., Li, Jing, Stevens, Bruce R., Pepine, Carl J., Raizada, Mohan K.

“…Hypertension is a worldwide problem with major impacts on health including morbidity and mortality, as well as consumption of health care resources. Nearly 50%…”
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Impaired Autonomic Nervous System-Microbiome Circuit in Hypertension: A Premise for Hypertension Therapy by Zubcevic, Jasenka, Richards, Elaine M., Yang, Tao, Kim, Seungbum, Sumners, Colin, Pepine, Carl J., Raizada, Mohan K.

“…Hypertension affects an estimated 103 million Americans, yet gaps in knowledge continue to limit its successful management. Rapidly emerging evidence is…”
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Brain–Gut–Bone Marrow Axis: Implications for Hypertension and Related Therapeutics by Santisteban, Monica M, Kim, Seungbum, Pepine, Carl J, Raizada, Mohan K

“…Hypertension is the most prevalent modifiable risk factor for cardiovascular disease and disorders directly influencing cardiovascular disease morbidity and…”
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Butyrate Regulates COVID-19–Relevant Genes in Gut Epithelial Organoids From Normotensive Rats by Li, Jing, Richards, Elaine M., Handberg, Eileen M., Pepine, Carl J., Raizada, Mohan K.

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Maternal Treatment With Captopril Persistently Alters Gut-Brain Communication and Attenuates Hypertension of Male Offspring by Li, Hong-Bao, Yang, Tao, Richards, Elaine M., Pepine, Carl J., Raizada, Mohan K.

“…Maternal-fetal crosstalk has been implicated in long-term control of the health of offspring, including transgenerational hypertension. However, current…”
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Microglial Cells Impact Gut Microbiota and Gut Pathology in Angiotensin II-Induced Hypertension by Sharma, Ravindra K, Yang, Tao, Oliveira, Aline C, Lobaton, Gilberto O, Aquino, Victor, Kim, Seungbum, Richards, Elaine M, Pepine, Carl J, Sumners, Colin, Raizada, Mohan K

“…RATIONALE:Increased microglial activation and neuroinflammation within autonomic brain regions have been implicated in sustained hypertension, and their…”
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Direct pro-inflammatory effects of prorenin on microglia by Shi, Peng, Grobe, Justin L, Desland, Fiona A, Zhou, Guannan, Shen, Xiao Z, Shan, Zhiying, Liu, Meng, Raizada, Mohan K, Sumners, Colin

“…Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we…”
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The Gut, Its Microbiome, and Hypertension by Richards, Elaine M., Pepine, Carl J., Raizada, Mohan K., Kim, Seungbum

“…Purpose of the Review Evidence is rapidly accumulating implicating gut dysbiosis in hypertension (HTN). However, we are far from understanding whether this is…”
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Critical Role of the Interaction Gut Microbiota - Sympathetic Nervous System in the Regulation of Blood Pressure by Toral, Marta, Robles-Vera, Iñaki, de la Visitación, Néstor, Romero, Miguel, Yang, Tao, Sánchez, Manuel, Gómez-Guzmán, Manuel, Jiménez, Rosario, Raizada, Mohan K, Duarte, Juan

“…Association between gut dysbiosis and neurogenic diseases, such as hypertension, has been described. The aim of this study was to investigate whether changes…”
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Pulmonary hypertension: Pathophysiology beyond the lung by Oliveira, Aline C., Richards, Elaine M., Raizada, Mohan K.

“…In a novel view of pulmonary hypertension (PH) pathophysiology as a systemic disease, a growing body of evidence indicates that bone marrow-derived cells, gut…”
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Depressive hypertension: A proposed human endotype of brain/gut microbiome dysbiosis by Stevens, Bruce R., Pepine, Carl J., Richards, Elaine M., Kim, Seungbum, Raizada, Mohan K.

“…Hypertension (HTN) is frequently linked with depression (DEP) in adults with cardiovascular disease (CVD), yet the underlying mechanism and successful…”
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Involvement of Bone Marrow Cells and Neuroinflammation in Hypertension by Santisteban, Monica M, Ahmari, Niousha, Carvajal, Jessica Marulanda, Zingler, Michael B, Qi, Yanfei, Kim, Seungbum, Joseph, Jessica, Garcia-Pereira, Fernando, Johnson, Richard D, Shenoy, Vinayak, Raizada, Mohan K, Zubcevic, Jasenka

“…RATIONALE:Microglial activation in autonomic brain regions is a hallmark of neuroinflammation in neurogenic hypertension. Despite evidence that an impaired…”
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Angiotensin-converting enzyme 2 and COVID-19 in cardiorenal diseases by Sharma, Ravindra K, Li, Jing, Krishnan, Suraj, Richards, Elaine M, Raizada, Mohan K, Mohandas, Rajesh

“…The rapid spread of the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought into focus the key role of…”
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