Search Results - "Raith, Mitch"

Obesity and inflammation influence pharmacokinetic profiles of PEG-based nanoparticles by Raith, Mitch, Nguyen, Nicole, Kauffman, Sarah J., Kang, Namgoo, Mays, Jimmy, Dalhaimer, Paul

“…Most patients that will be treated with soft nanoparticles (NPs) will be obese. Yet, NP testing, which begins with pharmacokinetic (PK) and toxicity studies,…”
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Inteins as tools for tagless and traceless protein purification by Lahiry, Ashwin, Fan, Yamin, Stimple, Samuel D, Raith, Mitch, Wood, David W

“…The purification of recombinant proteins is a complicated process that requires a thorough understanding of the physical and chemical properties of each…”
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PEGylated nanoparticles interact with macrophages independently of immune response factors and trigger a non-phagocytic, low-inflammatory response by Asoudeh, Monireh, Nguyen, Nicole, Raith, Mitch, Denman, Desiree S., Anozie, Uche C., Mokhtarnejad, Mahshid, Khomami, Bamin, Skotty, Kaitlyn M., Isaac, Sami, Gebhart, Taylor, Vaigneur, Lauren, Gelgie, Aga, Dego, Oudessa Kerro, Freeman, Trevor, Beever, Jon, Dalhaimer, Paul

“…Poly-ethylene-glycol (PEG)-based nanoparticles (NPs) - including cylindrical micelles (CNPs), spherical micelles (SNPs), and PEGylated liposomes (PLs) - are…”
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Elongated PEO-based nanoparticles bind the high-density lipoprotein (HDL) receptor scavenger receptor class B I (SR-BI) by Raith, Mitch, Kauffman, Sarah J., Asoudeh, Monireh, Buczek, Jennifer A., Kang, Nam-Goo, Mays, Jimmy W., Dalhaimer, Paul

“…Targeting cell-surface receptors with nanoparticles (NPs) is a crucial aspect of nanomedicine. Here, we show that soft, flexible, elongated NPs with…”
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