Search Results - "Raitano, Art"
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A cytoplasmic inhibitor of the JNK signal transduction pathway
Published in Science (American Association for the Advancement of Science) (01-08-1997)“…The c-Jun amino-terminal kinase (JNK) is a member of the stress-activated group of mitogen-activated protein (MAP) kineses that are implicated in the control…”
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1485: Development of GLUT-1 targeted boron carriers for Boron Neutron Capture Therapy (BNCT)
Published in Radiotherapy and oncology (01-05-2024)Get full text
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Organosilica nanoparticles containing sodium borocaptate (BSH) provide new prospects for boron neutron capture therapy (BNCT): efficient cellular uptake and enhanced BNCT efficacy
Published in Nanoscale advances (02-05-2023)“…Boron neutron capture therapy (BNCT), a method based on the fission of boron-10 upon neutron irradiation, has emerged as an attractive option for radiation…”
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Abstract 1086: Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family. It is activated by binding to its ligand, collagen and plays a key role…”
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Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Nectin-4 is a type I transmembrane antigen identified by Agensys to be highly expressed at the RNA level in a significant number of bladder and breast cancer…”
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Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Prostate stem cell antigen (PSCA) is a cysteine-rich cell surface glycoprotein expressed in about 50% of pancreatic and prostate cancers. AGS-PSCA is a…”
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Abstract 2590: Preclinical evaluation of ASG-5ME, a novel antibody-drug conjugate for pancreatic cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Antibody-drug conjugates (ADCs) have demonstrated promising activity and tolerability profiles in oncology clinical trials, including for Hodgkin lymphoma…”
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