Search Results - "Raiol, Milene"
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The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
Published in PloS one (16-02-2011)“…Based on pre-DNA racial/color methodology, clinical and pharmacological trials have traditionally considered the different geographical regions of Brazil as…”
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2
Association of apoptosis-related variants to malaria infection and parasite density in individuals from the Brazilian Amazon
Published in Malaria journal (04-10-2023)“…Abstract Background In malaria infection, apoptosis acts as an important immunomodulatory mechanism that leads to the elimination of parasitized cells, thus…”
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3
Investigation of INDEL variants in apoptosis: the relevance to gastric cancer
Published in BMC medical genetics (19-10-2020)“…Apoptosis is a type of cell death involved in different pathways inherent to the cell and the evasion from this mechanism has been related to cancer, although…”
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4
Strategy to improve malaria surveillance system preventing transfusion-transmitted malaria in blood banks using molecular diagnostic
Published in Malaria journal (01-10-2018)“…Malaria can be transmitted by blood transfusion through donations collected from asymptomatic or parasitic donors. The parasites are released into the…”
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Siaα2-3Galβ1- Receptor Genetic Variants Are Associated with Influenza A(H1N1)pdm09 Severity
Published in PloS one (05-10-2015)“…Different host genetic variants may be related to the virulence and transmissibility of pandemic Influenza A(H1N1)pdm09, influencing events such as binding of…”
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6
Association of the CYP2B6 gene with anti-tuberculosis drug-induced hepatotoxicity in a Brazilian Amazon population
Published in International journal of infectious diseases (01-04-2015)“…Highlights • Thirty-one patients out of 220 subjects developed drug-induced hepatotoxicity. • The results for the CYP3A5 gene were not significant among the…”
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7
Real-time PCR diagnosis of Plasmodium vivax among blood donors
Published in Malaria journal (12-10-2012)“…When selecting blood donors in transfusion centres, one important problem is to identify, during screening, individuals with infectious diseases that can be…”
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Comprehensive analysis of germline mutations in northern Brazil: a panel of 16 genes for hereditary cancer-predisposing syndrome investigation
Published in BMC cancer (07-04-2021)“…Next generation sequencing (NGS) has been a handy tool in clinical practice, mainly due to its efficiency and cost-effectiveness. It has been widely used in…”
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9
Human aging and somatic point mutations in mtDNA: A comparative study of generational differences (grandparents and grandchildren)
Published in Genetics and molecular biology (01-01-2011)“…The accumulation of somatic mutations in mtDNA is correlated with aging. In this work, we sought to identify somatic mutations in the HVS-1 region (D-loop) of…”
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10
CDH1 mutations in gastric cancer patients from northern Brazil identified by Next- Generation Sequencing (NGS)
Published in Genetics and molecular biology (13-05-2016)“…Gastric cancer is considered to be the fifth highest incident tumor worldwide and the third leading cause of cancer deaths. Developing regions report a higher…”
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11
Mixed Plasmodium malariae Infections Were Underdetected in a Malaria Endemic Area in the Amazon Region, Brazil
Published in The American journal of tropical medicine and hygiene (01-11-2021)“…Plasmodium malariae infections are often asymptomatic and long-lasting. Mixed infections are often underdetected in areas where P. malariae, P. vivax, and P…”
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12
Sia[alpha]2-3Gal[beta]1- Receptor Genetic Variants Are Associated with Influenza A(H1N1)pdm09 Severity
Published in PloS one (05-10-2015)“…Different host genetic variants may be related to the virulence and transmissibility of pandemic Influenza A(H1N1)pdm09, influencing events such as binding of…”
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13
Sia[alpha]2-3Gal[beta]1- Receptor Genetic Variants Are Associated with Influenza Apdm09 Severity
Published in PloS one (05-10-2015)“…Different host genetic variants may be related to the virulence and transmissibility of pandemic Influenza A(H1N1)pdm09, influencing events such as binding of…”
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14
A novel nonsense mutation of the KAL1 gene (p.Trp204) in Kallmann syndrome
Published in Application of clinical genetics (01-01-2014)“…To describe a novel KAL1 mutation in patients affected by Kallmann syndrome. Endocrinology Clinic of the João de Barros Barreto University Hospital - Federal…”
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15
Sia alpha 2-3Gal square 1- Receptor Genetic Variants Are Associated with Influenza A(H1N1)pdm09 Severity: e0139681
Published in PloS one (01-10-2015)“…Different host genetic variants may be related to the virulence and transmissibility of pandemic Influenza A(H1N1)pdm09, influencing events such as binding of…”
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16
CDH1 mutations in gastric cancer patients from northern Brazil identified by Next- Generation Sequencing (NGS)
Published in Genetics and molecular biology (01-01-2016)“…Abstract Gastric cancer is considered to be the fifth highest incident tumor worldwide and the third leading cause of cancer deaths. Developing regions report…”
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Journal Article -
17
A novel nonsense mutation of the KALI gene (p.Trp204 ) in Kallmann syndrome
Published in Application of clinical genetics (01-01-2014)“…Objective: To describe a novel KAL1 mutation in patients affected by Kallmann syndrome. Setting: Endocrinology Clinic of the Joao de Barros Barreto University…”
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18
Molecular Characterization of TP53 Gene in Human Populations Exposed to Low-Dose Ionizing Radiation
Published in BioMed research international (01-01-2013)“…Ionizing radiation, such as that emitted by uranium, may cause mutations and consequently lead to neoplasia in human cells. The TP53 gene acts to maintain…”
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19
A novel nonsense mutation of the KAL1 gene (p.Trp204) in Kallmann syndrome
Published in The application of clinical genetics (01-01-2014)“…OBJECTIVETo describe a novel KAL1 mutation in patients affected by Kallmann syndrome. SETTINGEndocrinology Clinic of the João de Barros Barreto University…”
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