Search Results - "Rainville, Vinciane"
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Detection of sarcoma fusions by a next-generation sequencing based–ligation-dependent multiplex RT-PCR assay
Published in Modern pathology (01-05-2022)“…Morphological, immunohistochemical, and molecular methods often need to be combined for accurate diagnosis and optimal clinical management of sarcomas. Here,…”
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Analysis of immunoglobulin/T‐cell receptor repertoires by high‐throughput RNA sequencing reveals a continuous dynamic of positive clonal selection in follicular lymphoma
Published in HemaSphere (01-02-2024)“…Follicular lymphoma (FL) course is highly variable, making its clinical management challenging. In this incurable and recurring pathology, the interval between…”
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Detection of salivary gland and sinonasal fusions by a next-generation sequencing based, ligation-dependent, multiplex RT-PCR assay
Published in Histopathology (01-11-2023)“…The discovery of tumour type-specific gene fusion oncogenes in benign and malignant salivary gland and sinonasal (SGSN) tumours has significantly increased our…”
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5′ Rapid amplification of cDNA ends (5′RACE): A simpler method to analyze immunoglobulin genes and discover the value of the light chain in chronic lymphocytic leukemia
Published in Leukemia research (01-12-2022)“…The mutational status of the variable region of the immunoglobulin heavy chain gene (IGHV) is a very important biomarker for chronic lymphocytic leukemia (CLL)…”
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Identification of primary mediastinal B-cell lymphomas with higher clonal dominance and poorer outcome using 5' RACE
Published in Blood advances (18-09-2024)“…Few data exist regarding the tumor B-cell receptor (BCR) repertoire and lymphoid microenvironment in primary mediastinal B-cell lymphoma (PMBL). We applied 5'…”
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High PDL1/PDL2 gene expression correlates with worse outcome in primary mediastinal large B-cell lymphoma
Published in Blood advances (12-12-2023)“…•PMBL patients with high gene expression of both PDL1 and PDL2 identified by GEP assay represent a subset of 23-30% of the population.•These patients have…”
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Benefit of cetuximab addition to a platinum–fluorouracil-based chemotherapy according to KRAS-LCS6 variant in an unselected population of recurrent and/or metastatic head and neck cancers
Published in European archives of oto-rhino-laryngology (01-02-2019)“…Objectives To evaluate the benefit of cetuximab (Cx) addition to platinum-based and 5-fluorouracil chemotherapy (PFU) in unselected recurrent and/or metastatic…”
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Phylogenetic Evolution in Refractory/Relapsed Diffuse Large B-Cell Lymphoma
Published in Blood (16-11-2012)“…Abstract 418 Diffuse large B-cell lymphoma (DLBCL) is the most common non-hodgkin lymphoma. It can be subdivided into two major subtypes with different gene…”
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Accurate Classification Of GCB/ABC and MYC/BCL2 Diffuse Large B-Cell Lymphoma With a 14 Genes Expression Signature and a Simple and Robust RT-MLPA Assay
Published in Blood (15-11-2013)“…Diffuse large B-cell lymphoma (DLBCL) is the most common non-hodgkin lymphoma. It is subdivided into two molecular subtypes called germinal center B cell-like…”
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Sμ mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells
Published in Blood (01-09-2008)“…Follicular lymphoma (FL) is a B-cell malignancy characterized by the t(14;18) translocation. Although sensitive to treatment, the disease remains incurable and…”
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Interim positron emission tomography scan associated with international prognostic index and germinal center B cell-like signature as prognostic index in diffuse large B-cell lymphoma
Published in Leukemia & lymphoma (01-01-2012)“…Abstract [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging is essential to optimize the initial staging and to predict the prognosis of…”
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The expression of BIRC5 is correlated with loss of specific chromosomal regions in breast carcinomas
Published in Genes chromosomes & cancer (01-04-2008)“…Expression of BIRC5 (survivin), a member of the inhibitor of apoptosis protein (IAP) family, is elevated in fetal tissues and in various human cancers…”
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Mutation mismatch repair gene deletions in diffuse large B-cell lymphoma
Published in Leukemia & lymphoma (01-05-2013)“…Abstract To further unravel the molecular pathogenesis of diffuse large B-cell lymphoma (DLBCL), we performed high-resolution comparative genomic hybridization…”
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A Quantitative Multiplex PCR Assay, Validated by a High Resolution Array Comparative Genomic Hybridization Analysis, Provides Information Regarding Genomic Imbalances and Prognosis in Diffuse Large B-Cell Lymphomas
Published in Blood (16-11-2006)“…Genomic gains and losses may play a crucial role in the development and progression of diffuse large B-cell lymphomas (DLBCL). Some gains or losses are…”
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S(mu) mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells
Published in Blood (01-09-2008)“…Follicular lymphoma (FL) is a B-cell malignancy characterized by the t(14;18) translocation. Although sensitive to treatment, the disease remains incurable and…”
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Journal Article