Search Results - "Raimund Strehl"

Coculture of Human Embryonic Stem Cells and Human Articular Chondrocytes Results in Significantly Altered Phenotype and Improved Chondrogenic Differentiation by Bigdeli, Narmin, Karlsson, Camilla, Strehl, Raimund, Concaro, Sebastian, Hyllner, Johan, Lindahl, Anders

“…Human embryonic stem (hES) cells have been suggested as a cell source for the repair of cartilage lesions. Here we studied how coculture with human articular…”
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Proteome of Personalized Tissue-Engineered Veins by Larsson, Susanna, Holmgren, Sandra, Jenndahl, Lachmi, Ulfenborg, Benjamin, Strehl, Raimund, Synnergren, Jane, Ghosheh, Nidal

“…Vascular diseases are the largest cause of death globally and impose a major global burden on healthcare. The gold standard for treating vascular diseases is…”
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Personalized tissue-engineered arteries as vascular graft transplants: A safety study in sheep by Jenndahl, Lachmi, Österberg, Klas, Bogestål, Yalda, Simsa, Robin, Gustafsson-Hedberg, Tobias, Stenlund, Patrik, Petronis, Sarunas, Krona, Annika, Fogelstrand, Per, Strehl, Raimund, Håkansson, Joakim

“…Patients with cardiovascular disease often need replacement or bypass of a diseased blood vessel. With disadvantages of both autologous blood vessels and…”
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Facilitated Expansion of Human Embryonic Stem Cells by Single‐Cell Enzymatic Dissociation by Ellerström, Catharina, Strehl, Raimund, Noaksson, Karin, Hyllner, Johan, Semb, Henrik

“…Traditionally, human embryonic stem cells (hESCs) are propagated by mechanical dissection or enzymatic dissociation into clusters of cells. To facilitate…”
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Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control by Serra, Margarida, Brito, Catarina, Sousa, Marcos F.Q., Jensen, Janne, Tostões, Rui, Clemente, João, Strehl, Raimund, Hyllner, Johan, Carrondo, Manuel J.T., Alves, Paula M.

“…The successful transfer of human embryonic stem cell (hESC) technology and cellular products into clinical and industrial applications needs to address issues…”
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Repair of Long Nerve Defects with a New Decellularized Nerve Graft in Rats and in Sheep by Contreras, Estefanía, Traserra, Sara, Bolívar, Sara, Forés, Joaquim, Jose-Cunilleras, Eduard, García, Felix, Delgado-Martínez, Ignacio, Holmgren, Sandra, Strehl, Raimund, Udina, Esther, Navarro, Xavier

“…Decellularized nerve allografts (DC) are an alternative to autografts (AG) for repairing severe peripheral nerve injuries. We have assessed a new DC provided…”
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The application of human embryonic stem cell technologies to drug discovery by Sartipy, Peter, Björquist, Petter, Strehl, Raimund, Hyllner, Johan

“…The isolation of human embryonic stem cells about a decade ago marked the birth of a new era in biomedical research. These pluripotent stem cells possess…”
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Creation of Engineered Human Embryonic Stem Cell Lines Using phiC31 Integrase by Thyagarajan, Bhaskar, Liu, Ying, Shin, Soojung, Lakshmipathy, Uma, Scheyhing, Kelly, Xue, Haipeng, Ellerström, Catharina, Strehl, Raimund, Hyllner, Johan, Rao, Mahendra S., Chesnut, Jonathan D.

“…It has previously been shown that the phage‐derived phiC31 integrase can efficiently target native pseudo‐attachment sites in the genome of various species in…”
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Adaptation of human embryonic stem cells to feeder-free and matrix-free culture conditions directly on plastic surfaces by Bigdeli, Narmin, Andersson, Maria, Strehl, Raimund, Emanuelsson, Katarina, Kilmare, Eva, Hyllner, Johan, Lindahl, Anders

“…Previous studies have shown that cultivation of undifferentiated human embryonic stem (hES) cells requires human fibroblasts (hF) or mouse embryonic fibroblast…”
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High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules by Andrews, Paul D, Becroft, Melissa, Aspegren, Anders, Gilmour, Jane, James, Martyn J, McRae, Scott, Kime, Robert, Allcock, Robert W, Abraham, Achamma, Jiang, Zhong, Strehl, Raimund, Mountford, Joanne C, Milligan, Graeme, Houslay, Miles D, Adams, David R, Frearson, Julie A

“…The propensity of human embryonic stem cells to die upon enzymatic disaggregation or low-density plating is an obstacle to their isolation and routine use in…”
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Long-term maintenance of human articular cartilage in culture for biomaterial testing by Strehl, Raimund, Tallheden, Tommi, Sjögren-Jansson, Eva, Minuth, Will W., Lindahl, Anders

“…Cartilage is a tissue that derives its unique mechanical and biological properties from the combination of relatively few cells and a large amount of a complex…”
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Partial identification of the mab CDAmp1 antigen at the epithelial–mesenchymal interface in the developing kidney by Strehl, Raimund, Minuth, Will W.

“…The nature of the primary functional events of nephron induction is still unknown, making it impossible to completely understand the mechanism of tissue…”
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Derivation of a Xeno‐Free Human Embryonic Stem Cell Line by Ellerström, Catharina, Strehl, Raimund, Moya, Karina, Andersson, Katarina, Bergh, Christina, Lundin, Kersti, Hyllner, Johan, Semb, Henrik

“…Elimination of all animal material during both the derivation and long‐term culture of human embryonic stem cells (hESCs) is necessary prior to future…”
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Derivation of Endothelial Cells From Human Embryonic Stem Cells by Directed Differentiation: Analysis of MicroRNA and Angiogenesis In Vitro and In Vivo by Kane, Nicole M, Meloni, Marco, Spencer, Helen L, Craig, Margaret A, Strehl, Raimund, Milligan, Graeme, Houslay, Miles D, Mountford, Joanne C, Emanueli, Costanza, Baker, Andrew H

“…OBJECTIVE—To develop an embryoid body-free directed differentiation protocol for the rapid generation of functional vascular endothelial cells derived from…”
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Individualized tissue‐engineered veins as vascular grafts: A proof of concept study in pig by Håkansson, Joakim, Simsa, Robin, Bogestål, Yalda, Jenndahl, Lachmi, Gustafsson‐Hedberg, Tobias, Petronis, Sarunas, Strehl, Raimund, Österberg, Klas

“…Personalized tissue engineered vascular grafts are a promising advanced therapy medicinal product alternative to autologous or synthetic vascular grafts…”
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Human embryonic stem cells: Current technologies and emerging industrial applications by Améen, Caroline, Strehl, Raimund, Björquist, Petter, Lindahl, Anders, Hyllner, Johan, Sartipy, Peter

“…Abstract The efficiency and accuracy of the drug development process is severely restricted by the lack of functional human cell systems. However, the…”
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Personalized tissue-engineered veins - long term safety, functionality and cellular transcriptome analysis in large animals by Österberg, Klas, Bogestål, Yalda, Jenndahl, Lachmi, Gustafsson-Hedberg, Tobias, Synnergren, Jane, Holmgren, Gustav, Bom, Eva, Petronis, Sarunas, Krona, Annika, Eriksson, Jonna S, Rosendahl, Jennifer, Crisostomo, Veronica, Sanchez-Margallo, Francisco M, Baez-Diaz, Claudia, Strehl, Raimund, Håkansson, Joakim

“…Tissue engineering is a promising methodology to produce advanced therapy medicinal products (ATMPs). We have developed personalized tissue engineered veins…”
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The Influence of Culture Media on Embryonic Renal Collecting Duct Cell Differentiation by Schumacher, Karl, Raimund Strehl, Sabine Kloth, Tauc, Michel, Will W. Minuth

“…During kidney development the embryonic ampullar collecting duct (CD) epithelium changes its function. The capability for nephron induction is lost and the…”
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Human embryonic stem cell-derived mesenchymal progenitors--potential in regenerative medicine by Karlsson, Camilla, Emanuelsson, Katarina, Wessberg, Fredrik, Kajic, Kristina, Axell, Mathilda Zetterström, Eriksson, Peter S, Lindahl, Anders, Hyllner, Johan, Strehl, Raimund

“…Tissue engineering and cell therapy require large-scale production of homogeneous populations of lineage-restricted progenitor cells that easily can be induced…”
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Human embryonic mesodermal progenitors highly resemble human mesenchymal stem cells and display high potential for tissue engineering applications by de Peppo, Giuseppe Maria, Svensson, Sara, Lennerås, Maria, Synnergren, Jane, Stenberg, Johan, Strehl, Raimund, Hyllner, Johan, Thomsen, Peter, Karlsson, Camilla

“…Adult stem cells, such as human mesenchymal stem cells (hMSCs), show limited proliferative capacity and, after long-term culture, lose their differentiation…”
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