Search Results - "Raimondi, Andrea"

ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress by Loi, Marisa, Raimondi, Andrea, Morone, Diego, Molinari, Maurizio

“…The endoplasmic reticulum (ER) produces about 40% of the nucleated cell’s proteome. ER size and content in molecular chaperones increase upon physiologic and…”
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Something Negative about Totality Facts by Raimondi, Andrea

“…Armstrong famously argued in favour of introducing totality facts in our ontology. Contrary to fully negative (absence) facts, totality facts yield a theory of…”
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Against the Quotational Theory of Meaning Ascriptions by Raimondi, Andrea

“…According to the quotational theory of meaning ascriptions, sentences like “‘Bruder (in German) means brother” are abbreviated synonymy claims, such as…”
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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation by Bononi, Angela, Giorgi, Carlotta, Patergnani, Simone, Larson, David, Verbruggen, Kaitlyn, Tanji, Mika, Pellegrini, Laura, Signorato, Valentina, Olivetto, Federica, Pastorino, Sandra, Nasu, Masaki, Napolitano, Andrea, Gaudino, Giovanni, Morris, Paul, Sakamoto, Greg, Ferris, Laura K., Danese, Alberto, Raimondi, Andrea, Tacchetti, Carlo, Kuchay, Shafi, Pass, Harvey I., Affar, El Bachir, Yang, Haining, Pinton, Paolo, Carbone, Michele

“…BRCA1-associated protein 1 (BAP1) regulates calcium flux in the endoplasmic reticulum to facilitate the execution of apoptosis, unveiling a new facet of the…”
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D’Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney by Festa, Beatrice Paola, Chen, Zhiyong, Berquez, Marine, Debaix, Huguette, Tokonami, Natsuko, Prange, Jenny Ann, Hoek, Glenn van de, Alessio, Cremonesi, Raimondi, Andrea, Nevo, Nathalie, Giles, Rachel H., Devuyst, Olivier, Luciani, Alessandro

“…The endolysosomal system sustains the reabsorptive activity of specialized epithelial cells. Lysosomal storage diseases such as nephropathic cystinosis cause a…”
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Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor by Ponsford, Amy H., Ryan, Thomas A., Raimondi, Andrea, Cocucci, Emanuele, Wycislo, Susanne A., Fröhlich, Florian, Swan, Laura E., Stagi, Massimiliano

“…Disorders of lysosomal physiology have increasingly been found to underlie the pathology of a rapidly growing cast of neurodevelopmental disorders and sporadic…”
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Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission by Milosevic, Ira, Giovedi, Silvia, Lou, Xuelin, Raimondi, Andrea, Collesi, Chiara, Shen, Hongying, Paradise, Summer, O'Toole, Eileen, Ferguson, Shawn, Cremona, Ottavio, De Camilli, Pietro

“…Endophilin is a membrane-binding protein with curvature-generating and -sensing properties that participates in clathrin-dependent endocytosis of synaptic…”
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Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control by Glytsou, Christina, Calvo, Enrique, Cogliati, Sara, Mehrotra, Arpit, Anastasia, Irene, Rigoni, Giovanni, Raimondi, Andrea, Shintani, Norihito, Loureiro, Marta, Vazquez, Jesùs, Pellegrini, Luca, Enriquez, Jose Antonio, Scorrano, Luca, Soriano, Maria Eugenia

“…The mitochondrial contact site and cristae organizing system (MICOS) and Optic atrophy 1 (OPA1) control cristae shape, thus affecting mitochondrial function…”
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TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress by Kucińska, Marika K., Fedry, Juliette, Galli, Carmela, Morone, Diego, Raimondi, Andrea, Soldà, Tatiana, Förster, Friedrich, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is an organelle of nucleated cells that produces proteins, lipids and oligosaccharides. ER volume and activity are increased…”
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Reticulon 3–dependent ER-PM contact sites control EGFR nonclathrin endocytosis by Caldieri, Giusi, Barbieri, Elisa, Nappo, Gilda, Raimondi, Andrea, Bonora, Massimo, Conte, Alexia, Verhoef, Lisette G. G. C., Confalonieri, Stefano, Malabarba, Maria Grazia, Bianchi, Fabrizio, Cuomo, Alessandro, Bonaldi, Tiziana, Martini, Emanuele, Mazza, Davide, Pinton, Paolo, Tacchetti, Carlo, Polo, Simona, Di Fiore, Pier Paolo, Sigismund, Sara

“…The integration of endocytic routes is critical to regulate receptor signaling. A nonclathrin endocytic (NCE) pathway of the epidermal growth factor receptor…”
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Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis by Anastasia, Irene, Ilacqua, Nicolò, Raimondi, Andrea, Lemieux, Philippe, Ghandehari-Alavijeh, Rana, Faure, Guilhem, Mekhedov, Sergei L., Williams, Kevin J., Caicci, Federico, Valle, Giorgio, Giacomello, Marta, Quiroga, Ariel D., Lehner, Richard, Miksis, Michael J., Toth, Katalin, de Aguiar Vallim, Thomas Q., Koonin, Eugene V., Scorrano, Luca, Pellegrini, Luca

“…Contacts between organelles create microdomains that play major roles in regulating key intracellular activities and signaling pathways, but whether they also…”
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Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency by Luciani, Alessandro, Schumann, Anke, Berquez, Marine, Chen, Zhiyong, Nieri, Daniela, Failli, Mario, Debaix, Huguette, Festa, Beatrice Paola, Tokonami, Natsuko, Raimondi, Andrea, Cremonesi, Alessio, Carrella, Diego, Forny, Patrick, Kölker, Stefan, Diomedi Camassei, Francesca, Diaz, Francisca, Moraes, Carlos T., Di Bernardo, Diego, Baumgartner, Matthias R., Devuyst, Olivier

“…Deregulation of mitochondrial network in terminally differentiated cells contributes to a broad spectrum of disorders. Methylmalonic acidemia (MMA) is one of…”
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Vices, Virtues, and Dispositions by Azzano, Lorenzo, Raimondi, Andrea

“…In this paper, we embark on the complicated discussion about the nature of vice in Virtue Ethics through a twofold approach: first, by taking seriously the…”
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Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits by Ferguson, Shawn, Raimondi, Andrea, Paradise, Summer, Shen, Hongying, Mesaki, Kumi, Ferguson, Agnes, Destaing, Olivier, Ko, Genevieve, Takasaki, Junko, Cremona, Ottavio, O' Toole, Eileen, De Camilli, Pietro

“…The GTPase dynamin, a key player in endocytic membrane fission, interacts with numerous proteins that regulate actin dynamics and generate/sense membrane…”
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PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development by Missiroli, Sonia, Bonora, Massimo, Patergnani, Simone, Poletti, Federica, Perrone, Mariasole, Gafà, Roberta, Magri, Eros, Raimondi, Andrea, Lanza, Giovanni, Tacchetti, Carlo, Kroemer, Guido, Pandolfi, Pier Paolo, Pinton, Paolo, Giorgi, Carlotta

“…The precise molecular mechanisms that coordinate apoptosis and autophagy in cancer remain to be determined. Here, we provide evidence that the tumor suppressor…”
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The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis by Fucci, Chiara, Resnati, Massimo, Riva, Elena, Perini, Tommaso, Ruggieri, Elena, Orfanelli, Ugo, Paradiso, Francesca, Cremasco, Floriana, Raimondi, Andrea, Pasqualetto, Elena, Nuvolone, Mario, Rampoldi, Luca, Cenci, Simone, Milan, Enrico

“…FAM46C is a non-canonical poly(A) polymerase uniquely mutated in up to 20% of multiple myeloma (MM) patients, implying a tissue-specific tumor suppressor…”
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The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane by Baskin, Jeremy M., Wu, Xudong, Christiano, Romain, Oh, Michael S., Schauder, Curtis M., Gazzerro, Elisabetta, Messa, Mirko, Baldassari, Simona, Assereto, Stefania, Biancheri, Roberta, Zara, Federico, Minetti, Carlo, Raimondi, Andrea, Simons, Mikael, Walther, Tobias C., Reinisch, Karin M., De Camilli, Pietro

“…Baskin et al.  report that FAM126A, which is mutated in hypomyelination and congenital cataract, regulates PI4KIII, the kinase generating PtdIns(4)P. Loss of…”
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Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude by Bakunts, Anush, Orsi, Andrea, Vitale, Milena, Cattaneo, Angela, Lari, Federica, Tadè, Laura, Sitia, Roberto, Raimondi, Andrea, Bachi, Angela, van Anken, Eelco

“…Insufficient folding capacity of the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to restore homeostasis. Yet, how the UPR achieves…”
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Identification of a membrane-less compartment regulating invadosome function and motility by Sala, Kristyna, Raimondi, Andrea, Tonoli, Diletta, Tacchetti, Carlo, de Curtis, Ivan

“…Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in…”
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