Search Results - "Raimondi, Ana R."
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A major role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes
Published in Frontiers in oncology (21-09-2022)“…Kaposi’s sarcoma (KS) is the most common tumor in AIDS patients. The highly vascularized patient’s skin lesions are composed of cells derived from the…”
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2
Treatment with Angiotensin-(1-7) Prevents Development of Oral Papilloma Induced in K-ras Transgenic Mice
Published in International journal of molecular sciences (26-03-2022)“…Oral Squamous Cell Carcinoma (OSCC) is the most common malignant cancer affecting the oral cavity. It is characterized by high morbidity and very few…”
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3
Rapamycin Prevents Early Onset of Tumorigenesis in an Oral-Specific K-ras and p53 Two-Hit Carcinogenesis Model
Published in Cancer research (Chicago, Ill.) (15-05-2009)“…Head and neck squamous cell carcinomas (HNSCC), the majority of which occur in the oral cavity, remain a significant cause of morbidity and mortality…”
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4
RUNX1 Is Regulated by Androgen Receptor to Promote Cancer Stem Markers and Chemotherapy Resistance in Triple Negative Breast Cancer
Published in Cells (Basel, Switzerland) (29-01-2023)“…Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype for which no effective targeted therapies are available. Growing evidence suggests…”
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Dissecting the Akt/Mammalian Target of Rapamycin Signaling Network: Emerging Results from the Head and Neck Cancer Tissue Array Initiative
Published in Clinical cancer research (01-09-2007)“…Purpose: As an approach to evaluate the expression pattern and status of activation of signaling pathways in clinical specimens from head and neck squamous…”
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Rapid Development of Salivary Gland Carcinomas upon Conditional Expression of K- ras Driven by the Cytokeratin 5 Promoter
Published in The American journal of pathology (01-05-2006)“…We have used a recently described model in which a ras oncogene is expressed in cytokeratin 5 (K5)-expressing cells on doxycycline administration to explore…”
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Oral-specific ablation of Klf4 disrupts epithelial terminal differentiation and increases premalignant lesions and carcinomas upon chemical carcinogenesis
Published in Journal of oral pathology & medicine (01-11-2015)“…Background Squamous cell carcinoma (SSC) of the head and neck is the sixth most common cancer and is rarely diagnosed in early stages. The transcription factor…”
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Impairing squamous differentiation by Klf4 deletion is sufficient to initiate tongue carcinoma development upon K-Ras activation in mice
Published in Carcinogenesis (New York) (01-03-2014)“…Oral squamous cell carcinoma (SCC) is among the most prevalent cancers in the world and is characterized by high morbidity and few therapeutic options. Like…”
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The alkynylphosphonate analogue of calcitriol EM1 has potent anti-metastatic effects in breast cancer
Published in The Journal of steroid biochemistry and molecular biology (01-11-2015)“…[Display omitted] •EM1 reduces the number of lung metastases in an animal model of breast cancer.•EM1 inhibits cellular migration and invasion in a breast…”
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Angiogenesis in potentially malignant lesions and carcinomas during experimental oral carcinogenesis: a preliminary study in the hamster cheek pouch
Published in Anticancer research (01-11-2014)“…To evaluate vascular morphology and density, angiogenic switch activation, vascular endothelial growth factor (VEGF) expression, and endothelial cell (EC)…”
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