Search Results - "Raiko, Juho"
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Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis
Published in Cell metabolism (07-08-2018)“…Human studies suggest that a meal elevates glucose uptake in brown adipose tissue (BAT). However, in postprandial state the thermogenic activity and the…”
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Associations Between Brain Gray Matter Volumes and Adipose Tissue Metabolism in Healthy Adults
Published in Obesity (Silver Spring, Md.) (01-03-2021)“…Objective Gray matter (GM) volume in different brain loci has been shown to vary in obesity and diabetes, and elevated fasting plasma nonesterified fatty acid…”
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Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus
Published in European journal of nuclear medicine and molecular imaging (01-09-2016)“…Purpose Brown adipose tissue (BAT) is considered a potential target for combatting obesity, as it produces heat instead of ATP in cellular respiration due to…”
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Human Brown Adipose Tissue Temperature and Fat Fraction Are Related to Its Metabolic Activity
Published in The journal of clinical endocrinology and metabolism (01-04-2017)“…Abstract Background and Aim: The metabolic activity of human brown adipose tissue (BAT) has been previously examined using positron emission tomography (PET)…”
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Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study
Published in Atherosclerosis (01-09-2012)“…Abstract Aims Hypofibrinolysis displayed by elevated serum plasminogen activator inhibitor 1 (PAI-1) level has been associated with cardiovascular disease…”
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6
Human Brown Fat Radiodensity Indicates Underlying Tissue Composition and Systemic Metabolic Health
Published in The journal of clinical endocrinology and metabolism (01-07-2017)“…Abstract Context: Metabolic imaging studying brown adipose tissue (BAT) physiology has increased, in which computed tomography (CT) is commonly used as an…”
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MR signal-fat-fraction analysis and T2 weighted imaging measure BAT reliably on humans without cold exposure
Published in Metabolism, clinical and experimental (01-05-2017)“…Abstract Objective Brown adipose tissue (BAT) is compositionally distinct from white adipose tissue (WAT) in terms of triglyceride and water content. In adult…”
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Resistance training improves skeletal muscle insulin sensitivity in elderly offspring of overweight and obese mothers
Published in Diabetologia (01-01-2016)“…Aims/hypothesis Maternal obesity predisposes offspring to adulthood morbidities, including type 2 diabetes. Type 2 diabetes and insulin resistance have been…”
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High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis
Published in European heart journal (01-09-2012)“…High-throughput metabolite quantification holds promise for cardiovascular risk assessment. Here, we evaluated whether metabolite quantification by nuclear…”
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Changes in electrocardiogram parameters during acute nonshivering cold exposure and associations with brown adipose tissue activity, plasma catecholamine levels, and brachial blood pressure in healthy adults
Published in Physiological reports (01-02-2021)“…Background Sympathetic activity causes changes in electrocardiogram (ECG) during cold exposure and the changes have been studied mostly during hypothermia and…”
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Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans
Published in Cell reports (Cambridge) (01-09-2023)“…Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for…”
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Imaging of Tumor Hypoxia With 18F-EF5 PET/MRI in Cervical Cancer
Published in Clinical nuclear medicine (01-12-2021)“…Purpose of the Report The aim of this study was to evaluate the distribution of hypoxia using 18 F-EF5 as a hypoxia tracer in cervical cancer patients with…”
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Femoral Bone Marrow Insulin Sensitivity Is Increased by Resistance Training in Elderly Female Offspring of Overweight and Obese Mothers
Published in PloS one (26-09-2016)“…Bone marrow insulin sensitivity may be an important factor for bone health in addition to bone mineral density especially in insulin resistant conditions…”
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Tracking of Noninvasive Ultrasound Measurements of Subclinical Atherosclerosis in Adulthood: Findings from the Cardiovascular Risk in Young Finns Study
Published in Ultrasound in medicine & biology (01-08-2010)“…Abstract We examined tracking of ultrasound measurements of vascular structure and function in adulthood using data collected in the 2001 and 2007 follow-ups…”
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Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study
Published in European journal of cardiovascular prevention and rehabilitation (01-10-2010)“…To study the utility of risk scores in the prediction of subclinical atherosclerosis in young adults. Participants were 2204 healthy Finnish adults aged 24-39…”
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High Brown Fat Activity Correlates With Cardiovascular Risk Factor Levels Cross-Sectionally and Subclinical Atherosclerosis at 5-Year Follow-Up
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2020)“…Brown adipose tissue (BAT) activity correlates negatively with obesity and insulin resistance, and BAT has been suggested to act as a protective factor against…”
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Imaging-based internal body temperature measurements: The journal Temperature toolbox
Published in Temperature (Austin) (01-10-2020)“…Noninvasive imaging methods of internal body temperature are in high demand in both clinical medicine and physiological research. Thermography and thermometry…”
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The tissue‐specific metabolic effects of the PPARα agonist ciprofibrate in insulin‐resistant male individuals: a double‐blind, randomized, placebo‐controlled crossover study
Published in Obesity (Silver Spring, Md.) (01-10-2023)“…Abstract Objective Insulin resistance is characterized by ectopic fat accumulation leading to cardiac diastolic dysfunction and nonalcoholic fatty liver…”
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Comparison of reprojected bone SPECT/CT and planar bone scintigraphy for the detection of bone metastases in breast and prostate cancer
Published in Nuclear medicine communications (01-05-2022)“…The aim of this study was to compare reprojected bone SPECT/CT (RBS) against planar bone scintigraphy (BS) in the detection of bone metastases in breast and…”
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Bone mineral density is increased after a 16-week resistance training intervention in elderly women with decreased muscle strength
Published in European journal of endocrinology (01-12-2016)“…Objective Non-pharmacological interventions are important in reducing risk for osteoporotic fractures. We investigated the effects of a 16-week individualized…”
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