Search Results - "Rai, Rajani"

Niclosamide causes lysosome-dependent cell death in endometrial cancer cells and tumors by Rai, Rajani, Dey, Debasish Kumar, Benbrook, Doris Mangiaracina, Chandra, Vishal

“…Endometrial cancer is the most common female cancer showing continuous rise in its incidence and mortality rate. Despite the extensive research efforts in…”
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Therapeutic options for management of endometrial hyperplasia by Chandra, Vishal, Kim, Jong Joo, Benbrook, Doris Mangiaracina, Dwivedi, Anila, Rai, Rajani

“…Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging from a slightly disordered pattern that exaggerates the alterations…”
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Independent and Combined Effects of Prenatal Alcohol Exposure and Prenatal Stress on Fetal HPA Axis Development by Bakhireva, Ludmila N, Solomon, Elizabeth, Roberts, Melissa H, Ma, Xingya, Rai, Rajani, Wiesel, Alexandria, Jacobson, Sandra W, Weinberg, Joanne, Milligan, Erin D

“…Prenatal alcohol exposure (PAE) and prenatal stress (PS) are highly prevalent conditions known to affect fetal programming of the…”
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Dataset on mucin 1 and 4 proteins and SialyT and T antigens staining patterns in cervical cancer primary tumors and metastatic lymph nodes by Rai, Rajani, Conrad, Rachel, Benbrook, Doris M.

“…The objective was to find an association between abnormal glycosylation, represented by Tn and STn antigens on mucin (MUC) proteins, in primary tumor specimens…”
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Similarities and Differences of Hsp70, hsc70, Grp78 and Mortalin as Cancer Biomarkers and Drug Targets by Rai, Rajani, Kennedy, Amy L, Isingizwe, Zitha Redempta, Javadian, Pouya, Benbrook, Doris Mangiaracina

“…: Upregulation of Heath Shock Protein 70 (HSP70) chaperones supports cancer cell survival. Their high homology causes a challenge to differentiate them in…”
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Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2 by Rai, Rajani, Chandra, Vishal, Kennedy, Amy L, Zuna, Rosemary E, Benbrook, Doris Mangiaracina

“…Drug-targetable vulnerabilities of cancer cells include their dependence on heat shock proteins (HSPs) to support elevated mitochondrial metabolism and…”
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A Multiple Interaction Analysis Reveals ADRB3 as a Potential Candidate for Gallbladder Cancer Predisposition via a Complex Interaction with Other Candidate Gene Variations by Rai, Rajani, Kim, Jong Joo, Misra, Sanjeev, Kumar, Ashok, Mittal, Balraj

“…Gallbladder cancer is the most common and a highly aggressive biliary tract malignancy with a dismal outcome. The pathogenesis of the disease is…”
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Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population by Rai, Rajani, Sharma, Kiran L, Sharma, Surbhi, Misra, Sanjeev, Kumar, Ashok, Mittal, Balraj

“…Defective apoptosis is a hallmark of cancer development and progression. Death receptors (DR4, FAS) and their ligands (TRAIL, FASL) are thought to mediate the…”
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Multi-analytic approach elucidates significant role of hormonal and hepatocanalicular transporter genetic variants in gallstone disease in North Indian population by Srivastava, Anshika, Mishra, Avshesh, Singh, Rajan, Rai, Rajani, Srivastava, Neena, Mittal, Balraj

“…Cholesterol gallstone disease (CGD) is a multifactorial and multistep disease. Apart from female gender and increasing age being the documented non-modifiable…”
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Discovery of Gene Sources for Economic Traits in Hanwoo by Whole-genome Resequencing by Shin, Younhee, Jung, Ho-Jin, Jung, Myunghee, Yoo, Seungil, Subramaniyam, Sathiyamoorthy, Markkandan, Kesavan, Kang, Jun-Mo, Rai, Rajani, Park, Junhyung, Kim, Jong-Joo

“…Hanwoo, a Korean native cattle (Bos taurus coreana), has great economic value due to high meat quality. Also, the breed has genetic variations that are…”
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Genome-wide Association Study to Identify Quantitative Trait Loci for Meat and Carcass Quality Traits in Berkshire by Iqbal, Asif, Kim, You-Sam, Kang, Jun-Mo, Lee, Yun-Mi, Rai, Rajani, Jung, Jong-Hyun, Oh, Dong-Yup, Nam, Ki-Chang, Lee, Hak-Kyo, Kim, Jong-Joo

“…Meat and carcass quality attributes are of crucial importance influencing consumer preference and profitability in the pork industry. A set of 400 Berkshire…”
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Expression profile of cholecystokinin type-A receptor in gallbladder cancer and gallstone disease by Rai, Rajani, Tewari, Mallika, Kumar, Mohan, Singh, Tej Bali, Shukla, Hari S

“…BACKGROUND:Regulatory peptide receptors have attracted the interest of oncologists as a new promising approach for cancer pathology,imaging and…”
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Manipulation of metabolic responses enhances SHetA2 efficacy without toxicity in cervical cancer cell lines and xenografts by Rai, Rajani, Lightfoot, Stanley, Benbrook, Doris Mangiaracina

“…The high frequency of cervical cancer recurrence after primary therapy necessitates alternative treatments. High-risk human papillomavirus (HR-HPV) causes…”
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Abstract 1252: The mechanism of the drug, SHetA2, in cervical cancer cells involves growth inhibition, mitochondria damage and release of AIF to cause caspase-independent cell death by Rai, Rajani, Chandra, Vishal, Benbrook, Doris M.

“…Abstract Introduction SHetA2 is an orally-bioavailable, novel small-molecule drug that is entering first in human trials for gynecologic cancers. Upon binding…”
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Automated Decision Support System for Focal Epilepsy Detection using Electroencephalogram by B, Rajani Rai, Joy Martis, Roshan

“…Epilepsy is a neurological disorder related to brain, which can be diagnosed using Electroencephalogram (EEG). The EEG consists of various rhythms that provide…”
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Abstract PR001: Preclinical development of SHetA2 for endometrial cancer therapy by Chandra, Vishal, Rai, Rajani, Benbrook, Doris M.

“…Abstract Introduction: SHetA2 (NSC 726189) is a novel drug that is entering first in human trials for gynecologic cancers. Upon binding to three related heat…”
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Abstract 6369: SHetA2 increases the activity of palbociclib in cervical cancer in vitro and in vivo by Bosley, Amy, Rai, Rajani, Benbrook, Doris M.

“…Abstract Introduction: Standard of care therapies for cervical cancer are harmful to normal cells and cause many side effects. New, less toxic treatments are…”
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Utility and Mechanism of SHetA2 and Paclitaxel for Treatment of Endometrial Cancer by Chandra, Vishal, Rai, Rajani, Benbrook, Doris Mangiaracina

“…Endometrial cancer patients with advanced disease or high recurrence risk are treated with chemotherapy. Our objective was to evaluate the utility and…”
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MicroRNA aberrations: An emerging field for gallbladder cancer management by Chandra, Vishal, Kim, Jong Joo, Mittal, Balraj, Rai, Rajani

“…Gallbladder cancer (GBC) is infrequent but most lethal biliary tract malignancy characterized by an advanced stage diagnosis and poor survival rates attributed…”
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The role and participation of immune cells in the endometrial tumor microenvironment by Dey, Debasish Kumar, Krause, Danielle, Rai, Rajani, Choudhary, Swati, Dockery, Lauren E., Chandra, Vishal

“…The tumor microenvironment is surrounded by blood vessels and consists of malignant, non-malignant, and immune cells, as well as signalling molecules, which…”
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