Search Results - "Rai, Niyati"
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1
Characterization of M. tuberculosis SerB2, an essential HAD-family phosphatase, reveals novel properties
Published in PloS one (18-12-2014)“…M. tuberculosis harbors an essential phosphoserine phosphatase (MtSerB2, Rv3042c) that contains two small- molecule binding ACT-domains (Pfam 01842) at the…”
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2
Mycobacterium tuberculosis class II apurinic/apyrimidinic‐endonuclease/3′‐5′ exonuclease III exhibits DNA regulated modes of interaction with the sliding DNA β‐clamp
Published in Molecular microbiology (01-10-2015)“…Summary The class‐II AP‐endonuclease (XthA) acts on abasic sites of damaged DNA in bacterial base excision repair. We identified that the sliding DNA β‐clamp…”
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3
Mycobacterium tuberculosis class II apurinic/apyrimidinic-endonuclease/3'-5' exonuclease III exhibits DNA regulated modes of interaction with the sliding DNA [Beta]-clamp
Published in Molecular microbiology (01-10-2015)“…The class-II AP-endonuclease (XthA) acts on abasic sites of damaged DNA in bacterial base excision repair. We identified that the sliding DNA β-clamp forms in…”
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4
Characterization of EccA3, a CbbX family ATPase from the ESX-3 secretion pathway of M. tuberculosis
Published in Biochimica et biophysica acta. Proteins and proteomics (01-06-2017)“…EccA family proteins are conserved components of ESX secretion pathways in M. tuberculosis H37Rv. Here, we report the characterization of EccA3 (Rv0282), a…”
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5
Critical determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3′–5′ exonuclease III
Published in Biochimica et biophysica acta (01-05-2015)“…The Mycobacterium tuberculosis AP-endonuclease/3′–5′ exodeoxyribonuclease (MtbXthA) is an important player in DNA base excision repair (BER). We demonstrate…”
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Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I
Published in Organic & biomolecular chemistry (21-05-2015)“…DNA ligases are critical components for DNA metabolism in all organisms. NAD(+)-dependent DNA ligases (LigA) found exclusively in bacteria and certain…”
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Biochemical and functional characterizations of tyrosine phosphatases from pathogenic and nonpathogenic mycobacteria: indication of phenyl cyclopropyl methyl-/phenyl butenyl azoles as tyrosine phosphatase inhibitors
Published in Applied microbiology and biotechnology (01-09-2015)“…Tyrosine phosphorylation is one of the most common means of posttranslational modifications which can generate novel recognition motifs for protein…”
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Identification of 1‑[4-Benzyloxyphenyl)-but-3-enyl]‑1H‑azoles as New Class of Antitubercular and Antimicrobial Agents
Published in ACS medicinal chemistry letters (10-10-2013)“…A series of 1-[(4-benzyloxyphenyl)-but-3-enyl]-1H-azoles has been identified as potent antitubercular agents against Mycobacterium tuberculosis. Synthesis of…”
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9
Characterization of M. tuberculosis SerB2, an Essential HAD-Family Phosphatase, Reveals Novel Properties: e115409
Published in PloS one (01-12-2014)“…M. tuberculosis harbors an essential phosphoserine phosphatase (MtSerB2, Rv3042c) that contains two small- molecule binding ACT-domains (Pfam 01842) at the…”
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Journal Article -
10
Expression analysis of genes responsible for amino acid biosynthesis in halophilic bacterium Salinibacter ruber
Published in Indian journal of biochemistry & biophysics (01-06-2013)“…The degeneracy of the genetic code allows for multiple codons to encode the same amino acid. However, alternative codons and amino acids are used unevenly…”
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11
Identification of 1-[4-Benzyloxyphenyl)-but-3-enyl]-1 H -azoles as New Class of Antitubercular and Antimicrobial Agents
Published in ACS medicinal chemistry letters (10-10-2013)Get full text
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12
Genome analysis of Rhizobium species using codon usage bias tools
Published in 2016 International Conference on Bioinformatics and Systems Biology (BSB) (01-03-2016)“…Bacteria from genus Rhizobium have ability to fix atmospheric nitrogen in symbiosis with leguminous plants resulting in formation of root nodules. They act as…”
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