Search Results - "Rai, Mohit Kumar"
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Short-Term Non-Steroid Anti-Inflammatory Drug Use in Spondyloarthritis Patients Induces Subclinical Acute Kidney Injury: Biomarkers Study
Published in Nephron (2015) (01-01-2017)“…Non-steroid anti-inflammatory drug (NSAID) usage is associated with kidney injury. Rise in serum creatinine (sCr) often represents irreversible process. Thus…”
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Development of the myocite biobank: Cost-efficient model of public sector investigator-driven biobank for idiopathic inflammatory myositis
Published in Indian journal of rheumatology (01-12-2020)“…Background: Biobanking refers to the cryopreservation of the various biologic samples for future research. In the era of omics, biobanking has emerged as a…”
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3
Indigenous primary culture protocols for human adult skin fibroblast, pancreatic stellate cells, and peritoneal fibroblasts
Published in Indian journal of rheumatology (01-07-2021)“…Despite availability of commercially available cell lines, primary cultures of cells remain the best available natural resource for in vitro research work…”
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Renal injury, biomarkers, and myositis, an understudied aspect of disease: prospective study in the MyoCite cohort
Published in Frontiers in medicine (22-06-2023)“…The mechanisms leading to chronic kidney disease (CKD) in patients with idiopathic inflammatory myopathies (IIMs) are poorly understood. We assessed the…”
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Histone deacetylase-2 inducer like theophylline has a potential to improve glucocorticoid responsiveness in severe uncontrolled asthma by reducing P-glycoprotein/MRP-1
Published in Indian journal of rheumatology (01-01-2022)“…Background: Epigenetic factors play an essential role in regulating the action of steroids in asthma. Steroids suppress inflammation by recruiting histone…”
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High serum myostatin level suggests accelerated muscle senescence in active idiopathic inflammatory myositis
Published in Indian journal of rheumatology (01-07-2021)“…Introduction: Inflammation is the forerunner to fibrosis and premature aging in various systemic diseases. Hence, we hypothesized that idiopathic inflammatory…”
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Lipid based drug delivery systems for oral, transdermal and parenteral delivery: Recent strategies for targeted delivery consistent with different clinical application
Published in Journal of drug delivery science and technology (01-08-2023)“…Lipid based drug delivery systems (LBDDS) are valuable and biocompatible nano-carriers for the vehiculation and potential delivery of various hydrophilic,…”
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Tacrolimus induces remission in refractory and relapsing lupus nephritis by decreasing P-glycoprotein expression and function on peripheral blood lymphocytes
Published in Rheumatology international (01-08-2022)“…P-glycoprotein (P-gp)-mediated efflux of corticosteroids (CS) may contribute to treatment unresponsiveness in Lupus Nephritis (LN) patients. Tacrolimus is a…”
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In Silico Prediction of NOS2, NOS3 and Arginase 1 Genes Targeting by Micro RNAs Upregulated in Systemic Sclerosis
Published in Indian journal of rheumatology (01-06-2024)“…Introduction: Systemic sclerosis (SSc) is a chronic disorder, characterised by endothelial dysfunction and fibrosis of skin and internal organs. Endothelium…”
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E025 Metformin reduces P-gp expression and potentiates anti-inflammatory action of corticosteroids
Published in Rheumatology (Oxford, England) (01-04-2019)Get full text
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Prognostic significance of circulating microparticles in IgA nephropathy
Published in International urology and nephrology (01-03-2024)“…Purpose Endothelial injury, involved in the pathogenesis of renal fibrosis, can generate microparticles (MPs). These are 0.1–1 µm membrane-bound vesicles shed…”
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ROLE OF IL-6 AND IL-17 MEDIATED INFLAMMATION AMPLIFIER LOOP IN CHRONIC ANTIBODY-MEDIATED REJECTION (CABMR)
Published in Transplantation (01-09-2020)Get full text
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Stimulation of Pancreatic Stellate Cells by IL-6/IL-17 upregulate ‘Inflammation Amplifier loop’: A Potential Therapeutic Target in Chronic Pancreatitis
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-12-2023)Get full text
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Clinical and Serological Associations of Subclinical Atherosclerosis in Systemic Sclerosis
Published in Indian journal of rheumatology (01-12-2024)“…Background: While patients with systemic sclerosis (SSc) are predisposed to cardiovascular events, data regarding this from India is sparse. We analysed…”
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Dual Enzyme Sequential Digestion Protocol for Isolation of Human Primary Chondrocytes From the Articular Cartilage Derived From Knee Osteoarthritis Patients
Published in Indian journal of rheumatology (01-06-2024)“…Introduction: Majority of available protocols for isolation of chondrocytes from articular cartilage tissue rely on the enzymatic digestion of the tissue by…”
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5-HT 2 and 5-HT 2B antagonists attenuate pro-fibrotic phenotype in human adult dermal fibroblasts by blocking TGF-β1 induced non-canonical signaling pathways including STAT3 : implications for fibrotic diseases like scleroderma
Published in International journal of rheumatic diseases (01-12-2018)“…Release of 5-hydroxytryptamine (5-HT; serotonin) from activated platelets following microvascular injury leads to tissue fibrosis. 5-HT strongly induces…”
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S1396 Response-Guided Ascites Mobilization in Patients of Acute on Chronic Liver Failure (ACLF) With Acute Kidney Injury Treated With Slow Albumin, Furosemide and Vasoconstrictor Therapy (SAFI+T) versus Standard Treatment
Published in The American journal of gastroenterology (01-10-2022)Get full text
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The prevalence and clinical characteristics of anti-HMGCR (anti-3-hydroxy-3-methyl-glutaryl-coenzyme A reductase) antibodies in idiopathic inflammatory myopathy: an analysis from the MyoCite registry
Published in Rheumatology international (01-07-2022)“…This study aimed to determine the prevalence and clinical characteristics of anti-HMGCR antibodies in idiopathic inflammatory myositis (IIM) at a tertiary care…”
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Clinical and Serological Associations of Subclinical Atherosclerosis in Spondyloarthropathy
Published in Indian journal of rheumatology (01-03-2024)“…Background: Patients with spondyloarthropathy (SpA) have a higher risk of subclinical atherosclerosis (SCA). We assessed clinical and serological determinants…”
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Utility of neutrophil CD64 and serum TREM-1 in distinguishing bacterial infection from disease flare in SLE and ANCA-associated vasculitis
Published in Clinical rheumatology (01-04-2019)“…Bacterial and opportunistic infections are a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE) and antineutrophil…”
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