Search Results - "Rai, Devendra K."

The Roles of Picornavirus Untranslated Regions in Infection and Innate Immunity by Kloc, Anna, Rai, Devendra K, Rieder, Elizabeth

“…Viral genomes have evolved to maximize their potential of overcoming host defense mechanisms and to induce a variety of disease syndromes. Structurally, a…”
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Analysis of some heavy metals in the riverine water, sediments and fish from river Ganges at Allahabad by Gupta, Aradhna, Rai, Devendra K, Pandey, Ravi S, Sharma, Bechan

“…The river Ganges has been one of the major recipients of industrial effluents in India. The present paper deals with the study related to occurrence and…”
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Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity by Rai, Devendra K, Diaz-San Segundo, Fayna, Campagnola, Grace, Keith, Anna, Schafer, Elizabeth A, Kloc, Anna, de Los Santos, Teresa, Peersen, Olve, Rieder, Elizabeth

“…Foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp) (3D ) catalyzes viral RNA synthesis. Its characteristic low fidelity and absence of…”
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The evolution of a super-swarm of foot-and-mouth disease virus in cattle by Arzt, Jonathan, Fish, Ian, Pauszek, Steven J, Johnson, Shannon L, Chain, Patrick S, Rai, Devendra K, Rieder, Elizabeth, Goldberg, Tony L, Rodriguez, Luis L, Stenfeldt, Carolina

“…Foot-and-mouth disease (FMD) is a highly contagious viral disease that severely impacts global food security and is one of the greatest constraints on…”
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Carbofuran-induced oxidative stress in mammalian brain by RAI, Devendra K, SHARMA, Bechan

“…Chronic exposure to carbofuran, a carbamate pesticide, via oral administration has been reported to generate reactive oxygen species (ROS) in rat brain…”
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Biochemical Mechanism of HIV-1 Resistance to Rilpivirine by Singh, Kamalendra, Marchand, Bruno, Rai, Devendra K., Sharma, Bechan, Michailidis, Eleftherios, Ryan, Emily M., Matzek, Kayla B., Leslie, Maxwell D., Hagedorn, Ariel N., Li, Zhe, Norden, Pieter R., Hachiya, Atsuko, Parniak, Michael A., Xu, Hong-Tao, Wainberg, Mark A., Sarafianos, Stefan G.

“…Rilpivirine (RPV) is a second generation nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) that efficiently inhibits HIV-1 resistant to first…”
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Homology modeling and analysis of structure predictions of the bovine rhinitis B virus RNA dependent RNA polymerase (RdRp) by Rai, Devendra K, Rieder, Elizabeth

“…Bovine Rhinitis B Virus (BRBV) is a picornavirus responsible for mild respiratory infection of cattle. It is probably the least characterized among the…”
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Effect of polymer blending on the electrochemical properties of porous PVDF/PMMA membrane immobilized with organic solvent based liquid electrolyte by Harshlata, Mishra, Kuldeep, Rai, Devendra K.

“…In this paper, experimental studies on blend gel polymer electrolyte membranes comprising of poly(vinylidene fluoride) (PVDF) and poly(methyl methacrylate)…”
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Determination of erythrocyte fragility as a marker of pesticide-induced membrane oxidative damage by Sharma, Bechan, Rai, Devendra K, Rai, Prashant Kumar, Rizvi, S I, Watal, Geeta

“…Erythrocytes are readily available cells and a good model system to study the health status of individuals with pathologic complications. It can also serve as…”
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Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase by Durk, Ryan C, Singh, Kamalendra, Cornelison, Ceili A, Rai, Devendra K, Matzek, Kayla B, Leslie, Maxwell D, Schafer, Elizabeth, Marchand, Bruno, Adedeji, Adeyemi, Michailidis, Eleftherios, Dorst, Christopher A, Moran, Jennifer, Pautler, Christie, Rodriguez, Luis L, McIntosh, Mark A, Rieder, Elizabeth

“…Background: Foot-and-Mouth Disease Virus (FMDV) is a picornavirus that infects cloven-hoofed animals and leads to severe losses in livestock production. In the…”
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Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase by Ndongwe, Tanyaradzwa P., Adedeji, Adeyemi O., Michailidis, Eleftherios, Ong, Yee Tsuey, Hachiya, Atsuko, Marchand, Bruno, Ryan, Emily M., Rai, Devendra K., Kirby, Karen A., Whatley, Angela S., Burke, Donald H., Johnson, Marc, Ding, Shilei, Zheng, Yi-Min, Liu, Shan-Lu, Kodama, Ei-Ichi, Delviks-Frankenberry, Krista A., Pathak, Vinay K., Mitsuya, Hiroaki, Parniak, Michael A., Singh, Kamalendra, Sarafianos, Stefan G.

“…We report key mechanistic differences between the reverse transcriptases (RT) of human immunodeficiency virus type-1 (HIV-1) and of xenotropic murine leukemia…”
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Residues within the Foot-and-Mouth Disease Virus 3Dpol Nuclear Localization Signal Affect Polymerase Fidelity by Kloc, Anna, Rai, Devendra K., Gladue, Douglas P., Schafer, Elizabeth, Kenney, Mary, Rieder, Elizabeth

“…In this study, we employed genetic and molecular dynamics approaches to analyze the role of individual amino acids of the FMDV 3D pol nuclear localization…”
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Residues within the Foot-and-Mouth Disease Virus 3D pol Nuclear Localization Signal Affect Polymerase Fidelity by Kloc, Anna, Rai, Devendra K, Gladue, Douglas P, Schafer, Elizabeth, Kenney, Mary, Rieder, Elizabeth

“…Many RNA viruses encode a proof-reading deficient, low-fidelity RNA-dependent polymerase (RdRp), which generates genetically diverse populations that can adapt…”
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Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study by Zhu, Yuao, Binder, Joe, Yurgelonis, Irina, Rai, Devendra K., Lazarro, Sarah, Costales, Chester, Kobylarz, Keith, McMonagle, Patricia, Steppan, Claire M., Aschenbrenner, Lisa, Anderson, Annaliesa S., Cardin, Rhonda D.

“…Vero cells are widely used for antiviral tests and virology research for SARS-CoV-2 as well as viruses from various other families. However, Vero cells…”
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Pathogenesis and micro-anatomic characterization of a cell-adapted mutant foot-and-mouth disease virus in cattle: Impact of the Jumonji C-domain containing protein 6 (JMJD6) and route of inoculation by Lawrence, Paul, Pacheco, Juan, Stenfeldt, Carolina, Arzt, Jonathan, Rai, Devendra K, Rieder, Elizabeth

“…Abstract A companion study reported Jumonji-C domain containing protein 6 (JMJD6) is involved in an integrin- and HS-independent pathway of FMDV infection in…”
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Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease by Mishra-Gorur, Ketu, Barak, Tanyeri, Kaulen, Leon D, Henegariu, Octavian, Jin, Sheng Chih, Aguilera, Stephanie Marie, Yalbir, Ezgi, Goles, Gizem, Nishimura, Sayoko, Miyagishima, Danielle, Djenoune, Lydia, Altinok, Selin, Rai, Devendra K, Viviano, Stephen, Prendergast, Andrew, Zerillo, Cynthia, Ozcan, Kent, Baran, Burcin, Sencar, Leman, Goc, Nukte, Yarman, Yanki, Ercan-Sencicek, A Gulhan, Bilguvar, Kaya, Lifton, Richard P, Moliterno, Jennifer, Louvi, Angeliki, Yuan, Shiaulou, Deniz, Engin, Brueckner, Martina, Gunel, Murat

“…While somatic variants of  (Tumor necrosis factor receptor-associated factor 7) underlie anterior skull-base meningiomas, here we report the inherited…”
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Reply to Pisan et al.: Pathogenicity of inherited TRAF7 mutations in congenital heart disease by Mishra-Gorur, Ketu, Barak, Tanyeri, Kaulen, Leon D, Henegariu, Octavian, Jin, Sheng Chih, Aguilera, Stephanie Marie, Yalbir, Ezgi, Goles, Gizem, Nishimura, Sayoko, Miyagishima, Danielle, Djenoune, Lydia, Altinok, Selin, Rai, Devendra K, Viviano, Stephen, Prendergast, Andrew, Zerillo, Cynthia, Ozcan, Kent, Baran, Burcin, Sencar, Leman, Goc, Nukte, Yarman, Yanki, Ercan-Encicek, A Gulhan, Bilguvar, Kaya, Lifton, Richard P, Moliterno, Jennifer, Louvi, Angeliki, Yuan, Shiaulou, Deniz, Engin, Brueckner, Martina, Gunel, Murat

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Bioinformatics and Molecular Analysis of the Evolutionary Relationship between Bovine Rhinitis A Viruses and Foot-And-Mouth Disease Virus by Rai, Devendra K., Lawrence, Paul, Pauszek, Steve J., Piccone, Maria E., Knowles, Nick J., Rieder, Elizabeth

“…Bovine rhinitis viruses (BRVs) cause mild respiratory disease of cattle. In this study, a near full-length genome sequence of a virus named RS3X (formerly…”
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Analysis of the interaction between host factor Sam68 and viral elements during foot-and-mouth disease virus infections by Rai, Devendra K, Lawrence, Paul, Kloc, Anna, Schafer, Elizabeth, Rieder, Elizabeth

“…The nuclear protein Src-associated protein of 68 kDa in mitosis (Sam68) is known to bind RNA and be involved in cellular processes triggered in response to…”
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Nirmatrelvir and molnupiravir maintain potent in vitro and in vivo antiviral activity against circulating SARS-CoV-2 omicron subvariants by Rosales, Romel, McGovern, Briana L., Rodriguez, M. Luis, Leiva-Rebollo, Rocio, Diaz-Tapia, Randy, Benjamin, Jared, Rai, Devendra K., Cardin, Rhonda D., Anderson, Annaliesa S., Alshammary, Hala, Banu, R., Farrugia, K., Gonzalez-Reiche, Ana Silvia, Paniz-Mondolfi, A., Polanco, J., Sordillo, Emilia Mia, van Bakel, Harm, Simon, Viviana, García-Sastre, Adolfo, White, Kris M.

“…Variants of SARS-CoV-2 pose significant challenges in public health due to their increased transmissibility and ability to evade natural immunity, vaccine…”
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