Search Results - "Rahul Kalla"

Ulcerative colitis: Recent advances in the understanding of disease pathogenesis [version 1; peer review: 2 approved] by Porter, Ross J, Kalla, Rahul, Ho, Gwo-Tzer

“…Inflammatory bowel diseases are common, complex, immune-mediated conditions with a sharply rising global prevalence. While major advances since 2000 have…”
Get full text

Precision medicine in inflammatory bowel disease: concept, progress and challenges [version 1; peer review: awaiting peer review] by Borg-Bartolo, Simon P, Boyapati, Ray Kiran, Satsangi, Jack, Kalla, Rahul

“…Crohn's disease and ulcerative colitis are increasingly prevalent, relapsing and remitting inflammatory bowel diseases (IBDs) with variable disease courses and…”
Get full text

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD by Boyapati, Ray K, Dorward, David A, Tamborska, Arina, Kalla, Rahul, Ventham, Nicholas T, Doherty, Mary K, Whitfield, Philip D, Gray, Mohini, Loane, Joseph, Rossi, Adriano G, Satsangi, Jack, Ho, Gwo-tzer

“…Abstract Background Due to common evolutionary origins, mitochondrial DNA (mtDNA) shares many similarities with immunogenic bacterial DNA. MtDNA is recognized…”
Get full text

Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases by Kalla, Rahul, Kennedy, Nicholas A, Ventham, Nicholas T, Boyapati, Ray K, Adams, Alex T, Nimmo, Elaine R, Visconti, Micaela R, Drummond, Hazel, Ho, Gwo-Tzer, Pattenden, Rebecca J, Wilson, David C, Satsangi, Jack

“…There is an unmet need for novel blood-based biomarkers that offer timely and accurate diagnostic and prognostic testing in inflammatory bowel diseases (IBD)…”
Get full text

The Role of Autologous Fecal Microbiota Transplantation in Diversion Colitis: A Case Report by Kalla, Rahul, Pitt, Mark, Sharma, Abhishek

Get full text

Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease by Zhang, Han, Kalla, Rahul, Chen, Jie, Zhao, Jianhui, Zhou, Xuan, Adams, Alex, Noble, Alexandra, Ventham, Nicholas T., Wellens, Judith, Ho, Gwo-Tzer, Dunlop, Malcolm G., Nowak, Jan Krzysztof, Ding, Yuan, Liu, Zhanju, Satsangi, Jack, Theodoratou, Evropi, Li, Xue

“…This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian…”
Get full text

Epigenetic alterations in inflammatory bowel disease: the complex interplay between genome-wide methylation alterations, germline variation, and gene expression by Kalla, Rahul, Dr, Adams, Alex, MBBS, Nimmo, Elaine, PhD, Kennedy, Nicholas, MRCP, Ventham, Nicholas, MRCS, Vatn, Morten, PhD, Jahnsen, Jorgen, PhD, Ricanek, Petr, PhD, Halfvarson, Jonas, PhD, Pierik, Marieke, PhD, Gomollon, Fernando, PhD, Gut, Ivo, PhD, D'Amato, Mauro, PhD, Satsangi, Jack, DPhil

“…Abstract Background Exploring DNA methylation in inflammatory bowel disease might provide an insight into the complex gene–environment interactions in disease…”
Get full text

Correction: changes to serum sample tube and processing methodology does not cause inter-individual variation in automated whole serum N-glycan profiling in health and disease by Ventham, Nicholas T, Gardner, Richard A, Kennedy, Nicholas A, Shubhakar, Archana, Kalla, Rahul, Nimmo, Elaine R, Fernandes, Daryl L, Satsangi, Jack, Spencer, Daniel I R

Get full text

case of inclusion body myositis responsive to prednisolone therapy by Kalla, Rahul, Soumakiyan, Majella, Tuck, Stephen

“…Inclusion body myositis, although rare, is the commonest cause of myopathy in patients aged over 50 years. The suggested pathogenesis remains uncertain and its…”
Get full text

Postoperative small bowel Crohn's disease: how to diagnose, manage and treat by Ip, Chak Lam, Boyapati, Ray, Kalla, Rahul

“…Crohn's disease is a relapsing inflammatory condition and disease recurrence after surgery is common. Significant variation in clinical practice remains…”
Get full text

Reply by Nowak, Jan Krzysztof, Kalla, Rahul, Satsangi, Jack

Get full text

Reply by Nowak, Jan Krzysztof, Kalla, Rahul, Satsangi, Jack

Get full text

Changes to serum sample tube and processing methodology does not cause Intra-Individual [corrected] variation in automated whole serum N-glycan profiling in health and disease by Ventham, Nicholas T, Gardner, Richard A, Kennedy, Nicholas A, Shubhakar, Archana, Kalla, Rahul, Nimmo, Elaine R, Fernandes, Daryl L, Satsangi, Jack, Spencer, Daniel I R

“…Serum N-glycans have been identified as putative biomarkers for numerous diseases. The impact of different serum sample tubes and processing methods on…”
Get full text

Age, Inflammation, and Disease Location Are Critical Determinants of Intestinal Expression of SARS-CoV-2 Receptor ACE2 and TMPRSS2 in Inflammatory Bowel Disease by Nowak, Jan Krzysztof, Lindstrøm, Jonas Christoffer, Kalla, Rahul, Ricanek, Petr, Halfvarson, Jonas, Satsangi, Jack

“…Although the respiratory tract is implicated as the primary portal of entry of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2),…”
Get full text

Current and emerging biomarkers for ulcerative colitis by Nowak, Jan K, Kalla, Rahul, Satsangi, Jack

“…Ulcerative colitis (UC) is a chronic illness requiring lifelong management that could be enhanced by personalizing care using biomarkers. The main biomarker…”
Get more information

A Case of IBD Immunosuppression Related Salmonella Aortitis Requiring Emergency Vascular Grafting by Sado, Abdulmaleek Idanesimhe, Kalla, Rahul, Sharma, Abishek

Get full text

Dietary Inflammatory Indices Are Not Associated With Inflammatory Bowel Disease Incidence and Progression by Wellens, Judith, Chen, Jie, Fu, Tian, Zhang, Yao, Kalla, Rahul, Satsangi, Jack, Theodoratou, Evropi, Li, Xue

“…Lay Summary Empirical dietary inflammatory pattern and the dietary inflammatory index are dietary inflammation indices, both previously associated with risk of…”
Get full text

Biomarkers in Search of Precision Medicine in IBD by Boyapati, Ray K, Kalla, Rahul, Satsangi, Jack, Ho, Gwo-Tzer

“…The completion of the human genome project in 2003 represented a major scientific landmark, ushering in a new era with hopes and expectations of fresh insights…”
Get full text

Treatment strategies and biomarkers in Crohn's disease: the PROFILE trial by Satsangi, Jack, Nowak, Jan, Kalla, Rahul, Colombel, Jean-Frederic

Get more information

Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis by Gasparetto, Marco, Payne, Felicity, Nayak, Komal, Kraiczy, Judith, Glemas, Claire, Philip-McKenzie, Yosef, Ross, Alexander, Edgar, Rachel D., Zerbino, Daniel R., Salvestrini, Camilla, Torrente, Franco, Ventham, Nicholas T., Kalla, Rahul, Satsangi, Jack, Sarkies, Peter, Heuschkel, Robert, Zilbauer, Matthias

“…Gene expression patterns of CD8+ T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed to…”
Get full text