Search Results - "Rahnavard, Ali"
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Multivariable association discovery in population-scale meta-omics studies
Published in PLoS computational biology (16-11-2021)“…It is challenging to associate features such as human health outcomes, diet, environmental conditions, or other metadata to microbial community measurements,…”
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2
Metabolite, protein, and tissue dysfunction associated with COVID-19 disease severity
Published in Scientific reports (16-07-2022)“…Proteins are direct products of the genome and metabolites are functional products of interactions between the host and other factors such as environment,…”
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3
Molecular epidemiology of pregnancy using omics data: advances, success stories, and challenges
Published in Journal of translational medicine (26-01-2024)“…Multi-omics approaches have been successfully applied to investigate pregnancy and health outcomes at a molecular and genetic level in several studies. As…”
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Epidemiological associations with genomic variation in SARS-CoV-2
Published in Scientific reports (26-11-2021)“…SARS-CoV-2 (CoV) is the etiological agent of the COVID-19 pandemic and evolves to evade both host immune systems and intervention strategies. We divided the…”
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Hospital antimicrobial stewardship: profiling the oral microbiome after exposure to COVID-19 and antibiotics
Published in Frontiers in microbiology (27-02-2024)“…During the COVID-19 Delta variant surge, the CLAIRE cross-sectional study sampled saliva from 120 hospitalized patients, 116 of whom had a positive COVID-19…”
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Impact of Fecal Microbiota Transplantation on Gut Bacterial Bile Acid Metabolism in Humans
Published in Nutrients (01-12-2022)“…Fecal microbiota transplantation (FMT) is a promising therapeutic modality for the treatment and prevention of metabolic disease. We previously conducted a…”
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7
Cervical cancer prediction by merging features of different colposcopic images and using ensemble classifier
Published in Journal of medical signals and sensors (01-04-2021)“…Background: Cervical cancer is a significant cause of cancer mortality in women, particularly in low-income countries. In regular cervical screening methods,…”
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8
Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression
Published in Frontiers in immunology (27-04-2021)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies predominantly to nuclear material. Many…”
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Estimating rare disease prevalence and costs in the USA: a cohort study approach using the Healthcare Cost Institute claims data
Published in BMJ Public Health (01-03-2024)“…Objective The study capitalised on national insurance claims data to gather information on patient characteristics and associated costs to better understand…”
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10
Protocol for meta-research on the evidence informing micronutrient dietary reference intakes for pregnant and lactating women
Published in Gates open research (2020)“…Nutrient reference values are important parameters that guide nutrition and public health work globally. Micronutrient requirements during the peri-conception…”
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11
Omics correlation for efficient network construction
Published in Nature Computational Science (01-04-2023)Get full text
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12
Differential expression of single‐cell RNA‐seq data using Tweedie models
Published in Statistics in medicine (15-08-2022)“…The performance of computational methods and software to identify differentially expressed features in single‐cell RNA‐sequencing (scRNA‐seq) has been shown to…”
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Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
Published in Cell host & microbe (14-08-2019)“…Obesity and type 2 diabetes (T2D) are metabolic disorders that are linked to microbiome alterations. However, their co-occurrence poses challenges in…”
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14
Omics community detection using multi-resolution clustering
Published in Bioinformatics (Oxford, England) (25-10-2021)“…Abstract Motivation The discovery of biologically interpretable and clinically actionable communities in heterogeneous omics data is a necessary first step…”
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15
Discovery of bioactive microbial gene products in inflammatory bowel disease
Published in Nature (London) (23-06-2022)“…Microbial communities and their associated bioactive compounds 1 – 3 are often disrupted in conditions such as the inflammatory bowel diseases (IBD) 4 …”
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High-sensitivity pattern discovery in large, paired multiomic datasets
Published in Bioinformatics (24-06-2022)“…Abstract Motivation Modern biological screens yield enormous numbers of measurements, and identifying and interpreting statistically significant associations…”
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Predictors of 30-Day Unplanned Readmission After Carotid Artery Stenting Using Artificial Intelligence
Published in Advances in therapy (01-06-2021)“…Introduction This study aimed to describe the rates and causes of unplanned readmissions within 30 days following carotid artery stenting (CAS) and to use…”
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Comprehensive profile of the companion animal gut microbiome integrating reference-based and reference-free methods
Published in The ISME Journal (08-01-2024)“…The gut microbiome of companion animals is relatively underexplored, despite its relevance to animal health, pet owner health, and basic microbial community…”
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An epidemiologic introduction to human metabolomic investigations
Published in Trends in endocrinology and metabolism (17-07-2023)“…Metabolomics holds great promise for uncovering insights around biological processes impacting disease in human epidemiological studies. Metabolites can be…”
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Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2024)“…Dietary lipids play an essential role in regulating the function of the gut microbiota and gastrointestinal tract, and these luminal interactions contribute to…”
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