Search Results - "Rahmati, Talat"

Presenilin Complexes with the C-Terminal Fragments of Amyloid Precursor Protein at the Sites of Amyloid β -Protein Generation by Xia, Weiming, Ray, William J., Ostaszewski, Beth L., Rahmati, Talat, Kimberly, W. Taylor, Wolfe, Michael S., Zhang, Jimin, Goate, Alison M., Selkoe, Dennis J.

“…An unusual intramembranous cleavage of the β -amyloid precursor protein (APP) by γ -secretase is the final step in the generation of amyloid β -peptide (Aβ )…”
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FAD Mutations in Presenilin-1 or Amyloid Precursor Protein Decrease the Efficacy of a γ-Secretase Inhibitor: Evidence for Direct Involvement of PS1 in the γ-Secretase Cleavage Complex by Xia, Weiming, Ostaszewski, Beth L., Kimberly, W.Taylor, Rahmati, Talat, Moore, Chad L., Wolfe, Michael S., Selkoe, Dennis J.

“…To investigate the mechanism of regulation of Aß production by familial Alzheimer's disease (FAD)-linked presenilin 1 (PS1), we used a cell-free system that…”
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Detection of toxigenic Bacillus cereus and Bacillus thuringiensis spores in U.S. rice by Ankolekar, Chandrakant, Rahmati, Talat, Labbé, Ronald G.

“…Bacillus cereus is a gram-positive, endospore forming pathogenic bacterium that is ubiquitous in the environment and is frequently associated with emetic and…”
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Growth of enterotoxigenic Bacillus cereus on salmon (Oncorhynchus nerka) by Labbé, Ronald, Rahmati, Talat

“…We previously demonstrated the widespread presence of enterotoxigenic Bacillus cereus in marine foods. In view of the widespread consumption of raw fish, we…”
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Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1 by Esler, W P, Kimberly, W T, Ostaszewski, B L, Diehl, T S, Moore, C L, Tsai, J Y, Rahmati, T, Xia, W, Selkoe, D J, Wolfe, M S

“…The beta-amyloid precursor protein (beta-APP), which is involved in the pathogenesis of Alzheimer's disease, and the Notch receptor, which is responsible for…”
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Detection of toxigenic Bacillus cereus and Bacillus thuringiensis spores in U.S. rice by ANKOLEKAR, Chandrakant, RAHMATI, Talat, LABBE, Ronald G

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The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for γ-Secretase Activity and Amyloid β-Protein Generation by Kimberly, W.Taylor, Xia, Weiming, Rahmati, Talat, Wolfe, Michael S., Selkoe, Dennis J.

“…The discovery that a deficiency of presenilin 1 (PS1) decreases the production of amyloid β-protein (Aβ) identified the presenilins as important mediators of…”
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Peptidomimetic Probes and Molecular Modeling Suggest That Alzheimer's γ-Secretase Is an Intramembrane-Cleaving Aspartyl Protease by Wolfe, Michael S, Xia, Weiming, Moore, Chad L, Leatherwood, Dartha D, Ostaszewski, Beth, Rahmati, Talat, Donkor, Isaac O, Selkoe, Dennis J

“…The amyloid β-protein (Aβ), implicated in the pathogenesis of Alzheimer's disease (AD), is a proteolytic metabolite generated by the sequential action of β-…”
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The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for γ-Secretase Activity and Amyloid β-Protein Generation by W. Taylor Kimberly, Weiming Xia, Talat Rahmati, Michael S. Wolfe, Dennis J. Selkoe

“…The discovery that a deficiency of presenilin 1 (PS1) decreases the production of amyloid β-protein (Aβ) identified the presenilins as important mediators of…”
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Localization of complexes of presenilin and the APP C-terminal fragments C83 and C99 to the subcellular sites of Aβgeneration by Xia, Weiming, Ray, William J., Ostaszewski, Beth L., Rahmati, Talat, Taylor Kimberly, W., Wolfe, Michael S., Goate, Alison M., Selkoe, Dennis J.

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Transition-state analogue inhibitors of -secretase bind directly to presenilin-1 by Wolfe, Michael S, Esler, William P, Kimberly, W. Taylor, Ostaszewski, Beth L, Diehl, Thekla S, Moore, Chad L, Tsai, Jui-Yi, Rahmati, Talat, Xia, Weiming, Selkoe, Dennis J

“…The beta-amyloid precursor protein (beta-APP), which is involved in the pathogenesis of Alzheimer's disease, and the Notch receptor, which is responsible for…”
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