Search Results - "Rahmanzadeh, Ramtin"
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Development and applications of photo-triggered theranostic agents
Published in Advanced drug delivery reviews (30-08-2010)“…Theranostics, the fusion of therapy and diagnostics for optimizing efficacy and safety of therapeutic regimes, is a growing field that is paving the way…”
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2
Photochemical Internalization with Fimaporfin: Enhanced Bleomycin Treatment for Head and Neck Cancer
Published in Pharmaceutics (28-07-2023)“…Head and neck squamous cell carcinoma (HNSCC) still represents the world’s sixth most common tumor entity, with increasing incidence. The reachability of light…”
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3
Ki-67 as a Molecular Target for Therapy in an In vitro Three-Dimensional Model for Ovarian Cancer
Published in Cancer research (Chicago, Ill.) (15-11-2010)“…Targeting molecular markers and pathways implicated in cancer cell growth is a promising avenue for developing effective therapies. Although the Ki-67 protein…”
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4
Influence of laser parameters on nanoparticle-induced membrane permeabilization
Published in Journal of Biomedical Optics (01-09-2009)“…Light-absorbing nanoparticles that are heated by short laser pulses can transiently increase membrane permeability. We evaluate the membrane permeability by…”
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5
Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b
Published in Journal of cancer research and clinical oncology (01-06-2016)“…Purpose Paclitaxel is an effective chemotherapeutic agent against various human tumors inducing apoptosis via binding to β-tubulin of microtubules and…”
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Light-Induced Liposomal Drug Delivery with an Amphiphilic Porphyrin and Its Chlorin and Bacteriochlorin Analogues
Published in Molecular pharmaceutics (05-02-2024)“…The development of targeted drug delivery mechanisms in the human body is a matter of growing interest in medical science. The selective release of therapeutic…”
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Chlorin-Based Photoactivable Galectin-3-Inhibitor Nanoliposome for Enhanced Photodynamic Therapy and NK Cell-Related Immunity in Melanoma
Published in ACS applied materials & interfaces (13-11-2019)“…Photodynamic therapy (PDT) is an encouraging alternative therapy for melanoma treatment and Ce6-mediated PDT has shown some exciting results in clinical…”
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Optically Controlled Drug Release from Light-Sensitive Liposomes with the New Photosensitizer 5,10-DiOH
Published in Molecular pharmaceutics (03-08-2020)“…The delivery of therapeutic drugs to a specific cellular site is a challenge in the treatment of different diseases. Liposomes have been widely studied as…”
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Light-Induced Permeabilization of Liposomes with a new Porphyrin and its Chlorin and Bacteriochlorin
Published in Photodiagnosis and photodynamic therapy (01-03-2023)“…The intracellular delivery of therapeutic agents is a central challenge in the treatment of different diseases. Light sensitive liposomes can release their…”
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10
Cancer cell‐specific protein delivery by optoporation with laser‐irradiated gold nanorods
Published in Journal of biophotonics (01-07-2020)“…ABSTRACT The delivery of macromolecules into living cells is challenging since in most cases molecules are endocytosed and remain in the endo‐lysosomal pathway…”
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Porphyrin-based sensor films for monitoring food spoilage
Published in Food packaging and shelf life (01-09-2023)“…To increase food safety and to minimize food waste, it is interesting for the food industry and consumers to be able to determine food spoilage continuously…”
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12
Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67
Published in Molecular pharmaceutics (08-09-2015)“…The selective inhibition of intracellular and nuclear molecules such as Ki-67 holds great promise for the treatment of cancer and other diseases. However, the…”
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13
Two ways to inactivate the Ki‐67 protein—Fragmentation by nanoparticles, crosslinking with fluorescent dyes
Published in Journal of biophotonics (01-09-2019)“…Light can manipulate molecular biological processes with high spatial and temporal precision and optical manipulation has become increasingly popular during…”
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14
A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67
Published in Scientific reports (01-06-2016)“…Using nanotechnology for optical manipulation of molecular processes in cells with high spatial and temporal precision promises new therapeutic options…”
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15
Indocyanine green as effective antibody conjugate for intracellular molecular targeted photodynamic therapy
Published in Journal of biomedical optics (01-07-2016)“…The fluorescent dye indocyanine green (ICG) is clinically approved and has been applied for ophthalmic and intraoperative angiography, measurement of cardiac…”
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Characterization of Micro‐ and Nanoscale LuPO4:Pr3+,Nd3+ with Strong UV‐C Emission to Reduce X‐Ray Doses in Radiation Therapy
Published in Particle & particle systems characterization (01-10-2019)“…UV‐C emitting nanoscale scintillators can be used to sensitize cancer cells selectively against X‐rays during radiation therapy, due to the lethal DNA lesions…”
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Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation
Published in International journal of nanomedicine (01-01-2017)“…Purpose: Pulsed-laser irradiation of light-absorbing gold nanoparticles (AuNPs) attached to cells transiently increases cell membrane permeability for targeted…”
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Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation
Published in International journal of nanomedicine (01-01-2017)“…Pulsed-laser irradiation of light-absorbing gold nanoparticles (AuNPs) attached to cells transiently increases cell membrane permeability for targeted molecule…”
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19
siRNA release from gold nanoparticles by nanosecond pulsed laser irradiation and analysis of the involved temperature increase
Published in Journal of biophotonics (01-09-2018)“…Nanosecond pulsed laser irradiation can trigger a release of nucleic acids from gold nanoparticles, but the involved nanoeffects are not fully understood yet…”
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Characterization of Micro‐ and Nanoscale LuPO 4 :Pr 3+ ,Nd 3+ with Strong UV‐C Emission to Reduce X‐Ray Doses in Radiation Therapy
Published in Particle & particle systems characterization (01-10-2019)“…UV‐C emitting nanoscale scintillators can be used to sensitize cancer cells selectively against X‐rays during radiation therapy, due to the lethal DNA lesions…”
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