Search Results - "Rahman Archie, Sabrina"
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Intraperitoneal Route of Drug Administration: Should it Be Used in Experimental Animal Studies?
Published in Pharmaceutical research (01-01-2020)“…Intraperitoneal (IP) route of drug administration in laboratory animals is a common practice in many in vivo studies of disease models. While this route is an…”
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Blood-Brain Barrier Dysfunction in CNS Disorders and Putative Therapeutic Targets: An Overview
Published in Pharmaceutics (26-10-2021)“…The blood-brain barrier (BBB) is a fundamental component of the central nervous system (CNS). Its functional and structural integrity is vital to maintain the…”
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Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping?
Published in International journal of molecular sciences (30-05-2020)“…The recently discovered novel coronavirus, SARS-CoV-2 (COVID-19 virus), has brought the whole world to standstill with critical challenges, affecting both…”
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Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective
Published in Frontiers in pharmacology (06-12-2019)“…Apart from being used as a medicine, cannabis or marijuana is the most widely abused recreational drug all over the world. The legalization and…”
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In vitro modeling of the neurovascular unit: advances in the field
Published in Fluids and barriers of the CNS (16-03-2020)“…The blood-brain barrier (BBB) is a fundamental component of the central nervous system. Its functional and structural integrity is vital in maintaining the…”
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Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes
Published in International journal of molecular sciences (31-07-2022)“…Proper regulation of energy metabolism in the brain is crucial for maintaining brain activity in physiological and different pathophysiological conditions…”
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Permeability of Metformin across an In Vitro Blood-Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)
Published in Pharmaceutics (28-04-2023)“…Our lab previously established that metformin, a first-line type two diabetes treatment, activates the Nrf2 pathway and improves post-stroke recovery…”
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Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age
Published in Fluids and barriers of the CNS (10-03-2023)“…Electronic nicotine delivery systems (ENDS), also commonly known as electronic cigarettes (e-cigs) are considered in most cases as a safer alternative to…”
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Recent Approaches for Solid Dose Vaccine Delivery
Published in Scientia pharmaceutica (01-12-2019)“…Recent studies on vaccine delivery systems are exploring the possibility of replacing liquid vaccines with solid dose vaccines due to the many advantages that…”
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Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping
Published in Fluids and barriers of the CNS (07-06-2022)“…Knowledge of the entry receptors responsible for SARS-CoV-2 is key to understand the neural transmission and pathogenesis of COVID-19 characterized by a…”
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Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function
Published in Frontiers in pharmacology (24-08-2023)“…Introduction: Despite the prevalence of the perception that electronic cigarettes (e-cig) are a safer alternative to tobacco smoke, growing concern about their…”
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Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
Published in Fluids and barriers of the CNS (09-09-2022)“…The short and long-term health effects of JUUL electronic cigarette (e-Cig) are largely unknown and warrant extensive research. We hypothesized that JUUL…”
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SYNTHESIS AND ANTIOXIDANT ACTIVITY OF 2-SUBSTITUTED-5-NITRO BENZIMIDAZOLE DERIVATIVES
Published in International journal of pharmacy and pharmaceutical sciences (31-12-2016)“…Objective: This study was conducted to synthesise some 2-substituted-5-nitro benzimidazole derivatives to evaluate their antioxidant activity.Methods: The…”
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Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective
Published in Neurotoxicology (Park Forest South) (01-03-2022)“…Accumulating evidence suggests that the detrimental effect of nicotine and tobacco smoke on the central nervous system (CNS) is caused by the neurotoxic role…”
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Public Health Policies on E-Cigarettes
Published in Current cardiology reports (01-10-2019)“…Tobacco continues to kill about 0.48 million Americans per year and there are currently 34.3 million smokers in the USA. As a consequence of the First Surgeon…”
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Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: a pharmacokinetic and pharmacodynamic perspective
Published in Neurotoxicology (Park Forest South) (09-02-2022)“…Accumulating evidence suggests that the detrimental effect of nicotine and tobacco smoke on the central nervous system (CNS) is caused by the neurotoxic role…”
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Prenatal E‐Cigarette Use Disrupts Blood‐Brain Barrier (BBB) Integrity and Induces Pro‐Inflammatory Cytokines in Postnatal Brain
Published in The FASEB journal (01-05-2022)“…Purpose Electronic cigarette (e‐Cig) is often considered as a safer alternative to smoking for pregnant women however, its potential toxic effect on neonatal…”
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The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice
Published in Pharmaceutical research (01-08-2024)“…Purpose We investigated whether short term infusion of propofol, a highly lipophilic agonist at GABA A receptors, which is in widespread clinical use as…”
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Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals
Published in Pharmaceutical research (01-11-2023)“…Purpose There is growing interest in seeking pharmacological activation of neurolysin (Nln) for stroke treatment. Discovery of central nervous system drugs…”
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