Search Results - "Rahman, Thuhairah Abdul"

Prevalence and associated factors of dysglycemia among patients with chronic obstructive pulmonary disease by Zulkifli, Khairil K, Mohamed Shah, Fatimah Z, Ismail, Ahmad I, Abdul Rahman, Thuhairah H, Ghani, Rohana A

“…Objectives Dysglycemia is known to be a common comorbidity of chronic obstructive pulmonary disease (COPD). However, undiagnosed dysglycemia and the associated…”
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Natural selection and local adaptation of blood pressure regulation and their perspectives on precision medicine in hypertension by Hoh, Boon-Peng, Abdul Rahman, Thuhairah, Yusoff, Khalid

“…Prevalence of hypertension (HTN) varies substantially across different populations. HTN is not only common - affecting at least one third of the world's adult…”
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Genomic structure of the native inhabitants of Peninsular Malaysia and North Borneo suggests complex human population history in Southeast Asia by Yew, Chee-Wei, Lu, Dongsheng, Deng, Lian, Wong, Lai-Ping, Ong, Rick Twee-Hee, Lu, Yan, Wang, Xiaoji, Yunus, Yushimah, Aghakhanian, Farhang, Mokhtar, Siti Shuhada, Hoque, Mohammad Zahirul, Voo, Christopher Lok-Yung, Abdul Rahman, Thuhairah, Bhak, Jong, Phipps, Maude E., Xu, Shuhua, Teo, Yik-Ying, Kumar, Subbiah Vijay, Hoh, Boon-Peng

“…Southeast Asia (SEA) is enriched with a complex history of peopling. Malaysia, which is located at the crossroads of SEA, has been recognized as one of the…”
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High prevalence of undiagnosed impaired glucose tolerance in patients with rheumatoid arthritis by Eddy Warman, Nur ‘Aini, Baharuddin, Hazlyna, Abdul Rahman, Thuhairah Hasrah, Ismail, Nurhuda, Ch’Ng, Shereen Suyin, Rosman, Azmillah, Abdul Ghani, Rohana

“…Objectives: Although the risk of diabetes mellitus has been recognised in rheumatoid arthritis, undiagnosed dysglycaemia remained under-reported. The study…”
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Observational study of the status of coronary risk biomarkers among Negritos with metabolic syndrome in the east coast of Malaysia by Mokhsin, Atiqah, Mokhtar, Siti Shuhada, Mohd Ismail, Aletza, M Nor, Fadzilah, Shaari, Syahrul Azlin, Nawawi, Hapizah, Yusoff, Khalid, Abdul Rahman, Thuhairah, Hoh, Boon Peng

“…ObjectivesTo determine the prevalence of metabolic syndrome (MS), ascertain the status of coronary risk biomarkers and establish the independent predictors of…”
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Differential positive selection of malaria resistance genes in three indigenous populations of Peninsular Malaysia by Liu, Xuanyao, Yunus, Yushimah, Lu, Dongsheng, Aghakhanian, Farhang, Saw, Woei-Yuh, Deng, Lian, Ali, Mohammad, Wang, Xu, Ghazali, Fadzilah, Abdul Rahman, Thuhairah, Shaari, Shahrul Azlin, Salleh, Mohd Zaki, Phipps, Maude E., Ong, Rick Twee-Hee, Xu, Shuhua, Teo, Yik-Ying, Hoh, Boon-Peng

“…The indigenous populations from Peninsular Malaysia, locally known as Orang Asli , continue to adopt an agro-subsistence nomadic lifestyle, residing primarily…”
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Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data by Ang, Geik Yong, Yu, Choo Yee, Subramaniam, Vinothini, Abdul Khalid, Mohd Ikhmal Hanif, Tuan Abdu Aziz, Tuan Azlin, Johari James, Richard, Ahmad, Aminuddin, Abdul Rahman, Thuhairah, Mohd Nor, Fadzilah, Ismail, Adzrool Idzwan, Md Isa, Kamarudzaman, Salleh, Hood, Teh, Lay Kek, Salleh, Mohd Zaki

“…The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism…”
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Significantly higher atherosclerosis risks in patients with obstructive sleep apnea and non-alcoholic fatty liver disease by Sukahri, Samshol, Mohamed Shah, Fatimah Zaherah, Ismail, Ahmad Izuanuddin, Koshy, Marymol, Johari, Bushra, Mohd Razali, Mazuin, Abdul Rahman, Thuhairah Hasrah, Isa, Mohamad Rodi, Abdul Ghani, Rohana

“…There is limited data on the relationship between Obstructive Sleep Apnea (OSA) and Non-Alcoholic Fatty Liver Disease (NAFLD), each associated with increased…”
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A study on the genetic polymorphisms of CYP3A5 among the Orang Asli in Malaysia using a next generation sequencing platform by Ang, Geik Yong, Yu, Choo Yee, Johari James, Richard, Ahmad, Aminuddin, Abdul Rahman, Thuhairah, Mohd Nor, Fadzilah, Shaari, Syahrul Azlin, Ismail, Adzrool Idzwan, Teh, Lay Kek, Salleh, Mohd Zaki

“…CYP3A5 is the predominant sub-family of biotransformation enzymes in the liver and the genetic variations in CYP3A5 are an important determinant of…”
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Safety and efficacy of very low carbohydrate diet in patients with diabetic kidney disease—A randomized controlled trial by Zainordin, Nur Aisyah, Eddy Warman, Nur' Aini, Mohamad, Aimi Fadilah, Abu Yazid, Fatin Aqilah, Ismail, Nazrul Hadi, Chen, Xin Wee, Koshy, Marymol, Abdul Rahman, Thuhairah Hasrah, Mohd Ismail, Nafeeza, Abdul Ghani, Rohana

“…Introduction There is limited data on the effects of low carbohydrate diets on renal outcomes particularly in patients with underlying diabetic kidney disease…”
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Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis by Rahman, Thuhairah Abdul, Hassim, Noor Faezah, Zulkafli, Nurmazni, Muid, Suhaila, Kornain, Noor Kaslina, Nawawi, Hapizah

“…Atherosclerosis is the main cause of coronary artery disease -related deaths worldwide. The atheroprotective properties of pure tocotrienols (T3) in the…”
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Effects of magnesium taurate on the onset and progression of galactose-induced experimental cataract: In vivo and in vitro evaluation by Agarwal, Renu, Iezhitsa, Igor, Awaludin, Nur Adilah, Ahmad Fisol, Nur Farhana, Bakar, Nor Salmah, Agarwal, Puneet, Abdul Rahman, Thuhairah Hasrah, Spasov, Alexander, Ozerov, Alexander, Mohamed Ahmed Salama, Mohamed Salama, Mohd Ismail, Nafeeza

“…Cataract, a leading cause of blindness, is characterized by lenticular opacities resulting from denaturation of lens proteins due to activation of…”
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Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations by Deng, Lian, Lou, Haiyi, Zhang, Xiaoxi, Thiruvahindrapuram, Bhooma, Lu, Dongsheng, Marshall, Christian R, Liu, Chang, Xie, Bo, Xu, Wanxing, Wong, Lai-Ping, Yew, Chee-Wei, Farhang, Aghakhanian, Ong, Rick Twee-Hee, Hoque, Mohammad Zahirul, Thuhairah, Abdul Rahman, Jong, Bhak, Phipps, Maude E, Scherer, Stephen W, Teo, Yik-Ying, Kumar, Subbiah Vijay, Hoh, Boon-Peng, Xu, Shuhua

“…Recent advances in genomic technologies have facilitated genome-wide investigation of human genetic variations. However, most efforts have focused on the major…”
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Diagnostic performance of various familial hypercholesterolaemia diagnostic criteria compared to Dutch lipid clinic criteria in an Asian population by Abdul-Razak, Suraya, Rahmat, Radzi, Mohd Kasim, Alicezah, Rahman, Thuhairah Abdul, Muid, Suhaila, Nasir, Nadzimah Mohd, Ibrahim, Zubin, Kasim, Sazzli, Ismail, Zaliha, Abdul Ghani, Rohana, Sanusi, Abdul Rais, Rosman, Azhari, Nawawi, Hapizah

“…Familial hypercholesterolaemia (FH) is a genetic disorder with a high risk of developing premature coronary artery disease that should be diagnosed as early as…”
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Relationships between severity of steatosis with glycemic control and carotid intima-media thickness among diabetic patients with ischemic heart disease by Omar, Nurazam, Koshy, Marymol, Hanafiah, Mohammad, Hatta, Sharifah, Shah, Fatimah, Johari, Bushra, Zamhuri, Idris, Kasim, Sazzli, Rahman, Thuhairah, Ghani, Rohana

“…Background: Nonalcoholic fatty liver disease (NAFLD) has become one of the major diseases plaguing worldwide. Several studies reported its association with…”
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Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data by Yu, Choo Yee, Ang, Geik Yong, Subramaniam, Vinothini, Johari James, Richard, Ahmad, Aminuddin, Abdul Rahman, Thuhairah, Mohd Nor, Fadzilah, Shaari, Syahrul Azlin, Teh, Lay Kek, Salleh, Mohd Zaki

“…CYP2D6 is one of the major enzymes in the cytochrome P450 monooxygenase system. It metabolizes ∼25% of prescribed drugs and hence, the genetic diversity of a…”
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Differential expression of AMPK subunit isoforms in subcutaneous adipose tissue of post-mortem subjects with BMI>25kg/m2 by Aznam, Norainfarahin Zainal, Rahman, Thuhairah Hasrah Abdul, Razali, Ruzi Hamimi, Ismail, Zaliha, Ismail, Aletza Mohd, Feng, Siew Sheue, Singh, Mansharan Kaur Chainchel

“…AMP-activated protein kinase (AMPK) is a heterotrimeric complex that is made up of α-, β- and γ- subunits isoforms making up various isomers. AMPK has been…”
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Prevalence and risk factors of metabolic syndrome among an endangered tribal population in Malaysia using harmonized IDF criteria by Ashari, Lydiatul Shima, Mitra, Amal K., Rahman, Thuhairah Abdul, Mitra, Amlan, Teh, Lay Kek, Salleh, Mohd Zaki, Mohamed, Hamid Jan B. Jan

“…The prevalence and risk factors associated with metabolic syndrome (MetS) of endangered subtribes are scantly reported. The purpose of this study was to assess…”
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Systematic characterization and comparison of the CYP2C9 variability of the Orang Asli in Malaysia with 12 populations by Teh, Lay Kek, Subramaniam, Vinothini, Tuan Abdu Aziz, Tuan Azlin, Lee, Lian Shien, Ismail, Mohamed Izwan, Yu, Choo Yee, Ang, Geik Yong, James Johari, Richard, Ismet, Rose Iszati, Sahak, Noor Saadah, Ahmad, Aminuddin, Rahman, Thuhairah Abdul, Nor @ Ghazali, Fadzilah Mohd, Shaari, SyahrulAzlin, Omar, Mustaffa, Ismail, Adzrool Idzwan, Md. Isa, Kamarudzaman, Salleh, Hood, Salleh, Mohd Zaki

“…We conducted a systematic characterization of CYP2C9 variants in 61 Orang Asli and 96 Singaporean Malays using the whole genome sequences data and compared the…”
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Study protocol of EMPOWER participatory action research (EMPOWER-PAR): a pragmatic cluster randomised controlled trial of multifaceted chronic disease management strategies to improve diabetes and hypertension outcomes in primary care by Ramli, Anis S, Lakshmanan, Sharmila, Haniff, Jamaiyah, Selvarajah, Sharmini, Tong, Seng F, Bujang, Mohamad-Adam, Abdul-Razak, Suraya, Shafie, Asrul A, Lee, Verna K M, Abdul-Rahman, Thuhairah H, Daud, Maryam H, Ng, Kien K, Ariffin, Farnaza, Abdul-Hamid, Hasidah, Mazapuspavina, Md-Yasin, Mat-Nasir, Nafiza, Miskan, Maizatullifah, Stanley-Ponniah, Jaya P, Ismail, Mastura, Chan, Chun W, Abdul-Rahman, Yong R, Chew, Boon-How, Low, Wilson H H

“…Chronic disease management presents enormous challenges to the primary care workforce because of the rising epidemic of cardiovascular risk factors. The…”
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