Search Results - "Rahman, M D Hasanur"
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Autophagy and Female Fertility: Mechanisms, Clinical Implications, and Emerging Therapies
Published in Cells (Basel, Switzerland) (01-08-2024)“…Autophagy, an evolutionarily conserved cellular mechanism essential for maintaining internal stability, plays a crucial function in female reproductive…”
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Therapeutic Aspects and Molecular Targets of Autophagy to Control Pancreatic Cancer Management
Published in Biomedicines (20-06-2022)“…Pancreatic cancer (PC) begins within the organ of the pancreas, which produces digestive enzymes, and is one of the formidable cancers for which appropriate…”
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An Update on the Study of the Molecular Mechanisms Involved in Autophagy during Bacterial Pathogenesis
Published in Biomedicines (05-08-2024)“…Autophagy is a unique catabolic process that degrades irrelevant or damaged components in eukaryotic cells to maintain homeostasis and eliminate infections…”
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Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease
Published in Biomedicines (29-04-2022)“…Alzheimer's disease (AD) is one of the most prevailing neurodegenerative diseases in the world, which is characterized by memory dysfunction and the formation…”
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Drug Target to Alleviate Mitochondrial Dysfunctions in Alzheimer's Disease: Recent Advances and Therapeutic Implications
Published in Current neuropharmacology (01-10-2024)“…Alzheimer's disease (AD) is a severe progressive neurodegenerative condition associated with neuronal damage and reduced cognitive function that primarily…”
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Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway
Published in Frontiers in pharmacology (07-05-2021)“…Bioactive plant derived compounds are important for a wide range of therapeutic applications, and some display promising anticancer properties. Further…”
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Protective effects of fucoidan against kidney diseases: Pharmacological insights and future perspectives
Published in International journal of biological macromolecules (01-06-2022)“…Chronic kidney disease (CKD) is a major public health concern that costs millions of lives worldwide. Natural products are consistently being explored for the…”
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Recent Advances in Ovarian Cancer: Therapeutic Strategies, Potential Biomarkers, and Technological Improvements
Published in Cells (Basel, Switzerland) (13-02-2022)“…Aggressive and recurrent gynecological cancers are associated with worse prognosis and a lack of effective therapeutic response. Ovarian cancer (OC) patients…”
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Candidate antiviral drugs for COVID-19 and their environmental implications: a comprehensive analysis
Published in Environmental science and pollution research international (01-11-2021)“…Emerging from Wuhan, China, SARS-CoV-2 is the new global threat that killed millions of people, and many are still suffering. This pandemic has not only…”
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Molecular Insights into the Multifunctional Role of Natural Compounds: Autophagy Modulation and Cancer Prevention
Published in Biomedicines (19-11-2020)“…Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein molecules and organelles in eukaryotic cells, which is controlled by…”
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An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1
Published in Life (Basel, Switzerland) (01-11-2022)“…Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic cytokine, namely transforming growth factor β (TGF-β) due to excessive…”
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Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer's Disease
Published in Biomedicines (24-12-2020)“…Alzheimer's disease (AD) is characterized by the formation of intracellular aggregate composed of heavily phosphorylated tau protein and extracellular deposit…”
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Potential Therapeutic Action of Autophagy in Gastric Cancer Managements: Novel Treatment Strategies and Pharmacological Interventions
Published in Frontiers in pharmacology (28-01-2022)“…Gastric cancer (GC), second most leading cause of cancer-associated mortality globally, is the cancer of gastrointestinal tract in which malignant cells form…”
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Potential Therapeutic Role of Phytochemicals to Mitigate Mitochondrial Dysfunctions in Alzheimer's Disease
Published in Antioxidants (01-01-2021)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a decline in cognitive function and neuronal damage. Although the precise…”
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Potential of Bioactive Food Components against Gastric Cancer: Insights into Molecular Mechanism and Therapeutic Targets
Published in Cancers (07-09-2021)“…Gastric cancer, also known as stomach cancer, is a cancer that develops from the lining of the stomach. Accumulated evidence and epidemiological studies have…”
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Curcumin analogs as the inhibitors of TLR4 pathway in inflammation and their drug like potentialities: a computer-based study
Published in Journal of receptors and signal transduction (03-07-2020)“…Toll-like receptor 4 (TLR4) pathway is one of the major pathways that mediate the inflammation in human body. There are different anti-inflammatory drugs…”
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Analysis of plant-derived phytochemicals as anti-cancer agents targeting cyclin dependent kinase-2, human topoisomerase IIa and vascular endothelial growth factor receptor-2
Published in Journal of receptors and signal transduction (04-05-2021)“…Cancer is caused by a variety of pathways, involving numerous types of enzymes. Among them three enzymes i.e. Cyclin-dependent kinase-2 (CDK-2), Human…”
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Analysis of SYK Gene as a Prognostic Biomarker and Suggested Potential Bioactive Phytochemicals as an Alternative Therapeutic Option for Colorectal Cancer: An In-Silico Pharmaco-Informatics Investigation
Published in Journal of personalized medicine (06-09-2021)“…SYK gene regulates the expression of SYK kinase (Spleen tyrosine kinase), an important non-receptor protein-tyrosine kinase for immunological receptor-mediated…”
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p53 Modulation of Autophagy Signaling in Cancer Therapies: Perspectives Mechanism and Therapeutic Targets
Published in Frontiers in cell and developmental biology (26-01-2022)“…The key tumor suppressor protein p53, additionally known as p53, represents an attractive target for the development and management of anti-cancer therapies…”
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Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol
Published in Phytomedicine (Stuttgart) (01-05-2022)“…Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids…”
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