Search Results - "Rahim, Awab Ghulam"
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Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial
Published in The Lancet (British edition) (14-09-2019)“…Primaquine is the only widely used drug that prevents Plasmodium vivax malaria relapses, but adherence to the standard 14-day regimen is poor. We aimed to…”
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COVID-19 and risks to the supply and quality of tests, drugs, and vaccines
Published in The Lancet global health (01-06-2020)Get full text
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Lineage-informative microhaplotypes for recurrence classification and spatio-temporal surveillance of Plasmodium vivax malaria parasites
Published in Nature communications (08-08-2024)“…Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of antimalarial efficacy and transmission. Recurrent infections may…”
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Weekly primaquine for radical cure of patients with Plasmodium vivax malaria and glucose-6-phosphate dehydrogenase deficiency
Published in PLoS neglected tropical diseases (06-09-2023)“…Background The World Health Organization recommends that primaquine should be given once weekly for 8-weeks to patients with Plasmodium vivax malaria and…”
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The heterogeneity of symptom reporting across study sites: a secondary analysis of a randomised placebo-controlled multicentre antimalarial trial
Published in BMC medical research methodology (04-09-2023)“…Introduction Symptoms reported following the administration of investigational drugs play an important role in decisions for registration and treatment…”
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Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction
Published in Malaria journal (25-02-2016)“…Combination therapy with artesunate plus sulfadoxine-pyrimethamine (SP) was adopted as recommended treatment for Plasmodium falciparum infection in Afghanistan…”
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Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial
Published in Malaria journal (21-04-2010)“…Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its…”
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A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms
Published in The New England journal of medicine (23-06-2016)“…The emergence of Plasmodium falciparum resistance to artemisinin-based therapy is a major global health challenge. In this report, investigators describe the…”
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Chloroquine-Primaquine versus Chloroquine Alone to Treat Vivax Malaria in Afghanistan: An Open Randomized Superiority Trial
Published in The American journal of tropical medicine and hygiene (01-12-2017)“…Afghanistan's national guidelines recommend primaquine (PQ) for radical treatment of malaria, but this is rarely implemented because of concerns over potential…”
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Provider and household costs of Plasmodium vivax malaria episodes: a multicountry comparative analysis of primary trial data
Published in Bulletin of the World Health Organization (01-12-2019)“…To determine household and health-care provider costs associated with infection across a range of endemic settings. We collected cost data alongside three…”
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Effect of adherence to primaquine on the risk of Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Published in Malaria journal (10-10-2023)“…Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax. This study investigated the effect of reduced adherence on the…”
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Provider and household costs of Plasmodium vivax malaria episodes: a multicountry comparative analysis of primary trial data/Cout des episodes de paludisme a Plasmodium vivax pour les menages et les prestataires: une analyse comparative multipays de donnees d'essais primaries/Costos del proveedor y del hogar de los episodios de malaria por Plasmodium vivax: un analisis comparativo multinacional de los datos del ensayo primario
Published in Bulletin of the World Health Organization (01-12-2019)“…Objective To determine household and health-care provider costs associated with Plasmodium vivax infection across a range of endemic settings. Methods We…”
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Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis
Published in Malaria journal (05-07-2019)“…Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they…”
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Improving the radical cure of vivax malaria (IMPROV): a study protocol for a multicentre randomised, placebo-controlled comparison of short and long course primaquine regimens
Published in BMC infectious diseases (07-12-2015)“…Plasmodium vivax malaria is a major cause of morbidity and recognised as an important contributor to mortality in some endemic areas. The current recommended…”
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