Stenotrophomonas maltophilia pneumonia in critical COVID-19 patients

Stenotrophomonas maltophilia pneumonia in critical COVID-19 patients

Stenotrophomonas maltophilia , an environmental aerobic non-fermentative Gram-negative bacilli, has gained attention in many nosocomial outbreaks. COVID-19 patients in intensive care unit have extended hospital stay and are severely immunosuppressed. This study aimed to determine the prevalence and...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports Vol. 13; no. 1; p. 3392
Main Authors: Raad, Marc, Abou Haidar, Marc, Ibrahim, Racha, Rahal, Rouba, Abou Jaoude, Jocelyne, Harmouche, Carine, Habr, Bassem, Ayoub, Eliane, Saliba, Gebrayel, Sleilaty, Ghassan, Mounzer, Karam, Saliba, Rindala, Riachy, Moussa
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 28-02-2023
Nature Publishing Group
Nature Portfolio
Subjects:
631/326
692/420/254
Aged
APACHE
Catheters
Coronaviruses
COVID-19
COVID-19 - epidemiology
Female
Gram-negative bacilli
Healthcare-Associated Pneumonia
Hospitals
Humanities and Social Sciences
Humans
Male
Medical instruments
Meropenem
Middle Aged
multidisciplinary
Nosocomial infection
Patients
Pneumonia
Risk factors
Science
Science (multidisciplinary)
Stenotrophomonas maltophilia
Thrombocytopenia
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Stenotrophomonas maltophilia , an environmental aerobic non-fermentative Gram-negative bacilli, has gained attention in many nosocomial outbreaks. COVID-19 patients in intensive care unit have extended hospital stay and are severely immunosuppressed. This study aimed to determine the prevalence and risk factors of S. maltophilia pneumonia in critical COVID-19 patients. A total of 123 COVID-19 patients in ICU admitted between March 2020 and March 2021 were identified from the authors’ institutional database and assessed for nosocomial pneumonia. Demographic data and factors predisposing to S. maltophilia pneumonia were collected and analyzed. The mean age was 66 ± 13 years and 74% were males. Median APACHE and SOFA scores were 13 (IQR = 8–19) and 4 (3–6), respectively. The Median NEWS2 score was 6 (Q1 = 5; Q3 = 8). The Median ICU stay was 12 (Q1 = 7; Q3 = 22) days. S.   maltophilia was found in 16.3% of pneumonia patients, leading to a lengthier hospital stay (34 vs. 20 days; p  < 0.001). Risk factors for S.   maltophilia pneumonia included previous treatment with meropenem ( p  < 0.01), thrombopenia ( p  = 0.034), endotracheal intubation ( p  < 0.001), foley catheter ( p  = 0.009) and central venous catheter insertion ( p  = 0.016). S. maltophilia nosocomial pneumonia is frequent in critical COVID-19 patients. Many significant risk factors should be addressed to reduce its prevalence and negative impact on outcomes.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-28438-x