Search Results - "Raguema, Nozha"
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Immune and Apoptosis Mechanisms Regulating Placental Development and Vascularization in Preeclampsia
Published in Frontiers in physiology (11-02-2020)“…Preeclampsia is the most severe type of hypertensive disorder of pregnancy, affecting one in 10 pregnancies worldwide and increasing significantly maternal and…”
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Selective Enrichment of Angiomirs in Extracellular Vesicles Released from Ischemic Skeletal Muscles: Potential Role in Angiogenesis and Neovascularization
Published in Cells (Basel, Switzerland) (01-08-2024)“…MicroRNAs (miRs) regulate physiological and pathological processes, including ischemia-induced angiogenesis and neovascularization. They can be transferred…”
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Contribution of angiotensinogen M235T and T174M gene variants and haplotypes to preeclampsia and its severity in (North African) Tunisians
Published in Journal of the renin-angiotensin-aldosterone system (01-01-2018)“…Background: Preeclampsia (PE) is a pregnancy-associated hypertensive disorder and a leading cause of maternal and neonatal morbidity and mortality. While its…”
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Stimulation of soluble guanylate cyclase activity with riociguat promotes angiogenesis and improves neovascularization after limb ischemia
Published in Atherosclerosis (01-05-2023)“…The NO-cGMP pathway is essential for angiogenesis, vasculogenesis and post-natal neovascularization. The key enzyme responsible for the synthesis of cGMP…”
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Abstract 14936: Profiling of Microrna Expression in Extracellular Vesicles Released From Ischemic Skeletal Muscles in Hypercholesterolemic Conditions
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionHypercholesterolemia (HC) is an important cardiovascular risk factor associated with impaired neovascularization in response to ischemia. We found…”
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Abstract 15061: Role of Exosomal Microrna-21a-5p in the Modulation of Ischemia-Induced Angiogenesis in Hypercholesterolemic Conditions
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionExtracellular vesicles (EVs) and their MicroRNA (miR) content are involved in several physiological processes, including the response to ischemia…”
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Abstract P104: Activation of Endoplasmic Reticulum Stress and Thrombospondin-1 Anti-Angiogenic Mechanisms in Placentas of Hypertensive Mice
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Background: Thrombospondin-1 (Thbs1) is an anti-angiogenic focal adhesion glycoprotein. It binds to receptors CD36, LRP1 and CD47 activating…”
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Abstract 148: Sex-Differences in Fetal Programming of Cardiomyopathy Induced by Hypertensive Disorders of Pregnancy in Mice
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Background: Hypertensive disorders reach one in ten pregnancies worldwide, significantly increasing rates of maternal and neonatal morbidity and…”
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Contribution of -1031T/C and -376G/A tumor necrosis factor alpha polymorphisms and haplotypes to preeclampsia risk in Tunisia (North Africa)
Published in Journal of reproductive immunology (01-02-2022)“…•The minor allele TNF-α -1031C polymorphism is associated with preeclampsia.•-1031C and -376A (CA) haplotype was associated with a higher incidence of…”
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Preeclampsia is associated with reduced renin, aldosterone, and PlGF levels, and increased sFlt-1/PlGF ratio, and specific angiotensin-converting enzyme Ins-Del gene variants
Published in Journal of reproductive immunology (01-06-2023)“…We investigated the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism with preeclampsia (PE) in Tunisian women. ACE I/D…”
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Relation of rs846910, rs4844880 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1) polymorphisms with the risk of preeclampsia: A case-control study
Published in Gene reports (01-12-2024)“…The 11β-hydroxysteroid-dehydrogenase 1 (11β-HSD1) enzyme catalyzes the interconversion of cortisone and cortisol, with mainly oxoreductive activity in intact…”
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Vascular endothelial growth factor single nucleotide polymorphisms and haplotypes in pre-eclampsia: A case-control study
Published in Cytokine (Philadelphia, Pa.) (01-09-2017)“…•We genotyped ten genetic markers in the VEGF-A gene with preeclampsia (PE).•Lack of association of the genotypes of VEGFA SNPs with PE.•Positive association…”
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MMP-2 and MMP-9 Polymorphisms and Preeclampsia Risk in Tunisian Arabs: A Case-Control Study
Published in Journal of clinical medicine (16-06-2021)“…The abnormal production of matrix metalloproteinases (MMPs), especially MMP-9 and MMP-2, plays a pivotal role in hypertensive disorders of pregnancy, and as…”
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Increased physical activity is correlated with improved pregnancy outcomes in women with preeclampsia: A retrospective study
Published in Pregnancy hypertension (01-07-2020)“…•Women with preeclampsia engage in more sedentary activities than controls.•Physical activity is positively correlated with the duration of pregnancy.•Physical…”
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Association of common eNOS/NOS3 polymorphisms with preeclampsia in Tunisian Arabs
Published in Gene (15-09-2015)“…We investigated the association of endothelial nitric oxide synthase (NOS3) polymorphisms −786T>C, 27-bp repeat 4b/4a, and Glu298Asp with preeclampsia (PE)…”
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Placental growth factor and vascular endothelial growth factor serum levels in Tunisian Arab women with suspected preeclampsia
Published in Cytokine (Philadelphia, Pa.) (01-03-2016)“…•We quantitated the PIGF and VEGF plasma levels in Tunisian Arab women.•We established the range of VEGF and PIGF in normal healthy pregnancies.•Reduced PIGF…”
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FGF1 and FGF2 mutations in preeclampsia and related features
Published in Placenta (Eastbourne) (01-07-2016)“…Abstract Background Fibroblast growth factor ( FGF ) 1 and FGF 2 were previously linked with preeclampsia (PE), possibly through altering decidual and…”
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Association of common eNOS/NOS sub(3) polymorphisms with preeclampsia in Tunisian Arabs
Published in Gene (01-09-2015)“…We investigated the association of endothelial nitric oxide synthase (NOS sub(3)) polymorphisms -786T>C, 27-bp repeat 4b/4a, and Glu298Asp with preeclampsia…”
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