Search Results - "Ragozzino, D."

Microglial diversity along the hippocampal longitudinal axis impacts synaptic plasticity in adult male mice under homeostatic conditions by De Felice, E, Gonçalves de Andrade, E, Golia, M T, González Ibáñez, F, Khakpour, M, Di Castro, M A, Garofalo, S, Di Pietro, E, Benatti, C, Brunello, N, Tascedda, F, Kaminska, B, Limatola, C, Ragozzino, D, Tremblay, M E, Alboni, S, Maggi, L

“…The hippocampus is a plastic brain area that shows functional segregation along its longitudinal axis, reflected by a higher level of long-term potentiation…”
Get full text

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages by Grimaldi, A, D'Alessandro, G, Golia, M T, Grössinger, E M, Di Angelantonio, S, Ragozzino, D, Santoro, A, Esposito, V, Wulff, H, Catalano, M, Limatola, C

“…Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by…”
Get full text

Anomalous Levels of Cl⁻ Transporters in the Hippocampal Subiculum from Temporal Lobe Epilepsy Patients Make GABA Excitatory by Palma, E., Amici, M., Sobrero, F., Spinelli, G., Di Angelantonio, S., Ragozzino, D., Mascia, A., Scoppetta, C., Esposito, V., Miledi, R., Eusebi, F.

“…The mRNA levels of NKCC1, an inwardly directed Na⁺, K⁺-2Cl⁻ cotransporter that facilitates the accumulation of intracellular Cl⁻, and of KCC2, an outwardly…”
Get full text

ATP release during cell swelling activates a Ca2+-dependent Cl− current by autocrine mechanism in mouse hippocampal microglia by Murana, E., Pagani, F., Basilico, B., Sundukova, M., Batti, L., Di Angelantonio, S., Cortese, B., Grimaldi, A., Francioso, A., Heppenstall, P., Bregestovski, P., Limatola, C., Ragozzino, D.

“…Microglia cells, resident immune cells of the brain, survey brain parenchyma by dynamically extending and retracting their processes. Cl − channels, activated…”
Get full text

CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes by Piccinin, S, Di Angelantonio, S, Piccioni, A, Volpini, R, Cristalli, G, Fredholm, B B, Limatola, C, Eusebi, F, Ragozzino, D

“…We characterized the role of adenosine receptor (AR) subtypes in the modulation of glutamatergic neurotransmission by the chemokine fractalkine (CX3CL1) in…”
Get full text

CXC Chemokine Receptors in the Central Nervous System: Role in Cerebellar Neuromodulation and Development by Ragozzino, Davide

“…Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells. Much evidence suggests…”
Get full text

A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium by Di Angelantonio, S, Murana, E, Cocco, S, Scala, F, Bertollini, C, Molinari, M G, Lauro, C, Bregestovski, P, Limatola, C, Ragozzino, D

“…Glioma patients commonly suffer from epileptic seizures. However, the mechanisms of glioma-associated epilepsy are far to be completely understood. Using…”
Get full text

Rundown of GABA Type A Receptors Is a Dysfunction Associated with Human Drug-Resistant Mesial Temporal Lobe Epilepsy by D. Ragozzino, Palma, E., Di Angelantonio, S., M. Amici, A. Mascia, Arcella, A., F. Giangaspero, Cantore, G., Di Gennaro, G., Manfredi, M., Esposito, V., Quarato, P. P., Miledi, R., Eusebi, F.

“…Pharmacotherapeutic strategies have been difficult to develop for several forms of temporal lobe epilepsy, which are consequently treated by surgical…”
Get full text

Phosphatase Inhibitors Remove the Run-Down of γ-Aminobutyric Acid Type A Receptors in the Human Epileptic Brain by Palma, E., Ragozzino, D. A., Di Angelantonio, S., Spinelli, G., Trettel, F., Martinez-Torres, A., Torchia, G., Arcella, A., Di Gennaro, G., Quarato, P. P., Esposito, V., Cantore, G., Miledi, R., Eusebi, F.

“…The properties of γ-aminobutyric acid (GABA) type A receptors ( GABA A receptors) microtransplanted from the human epileptic brain to the plasma membrane of…”
Get full text

Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells by Lax, P, Limatola, C, Fucile, S, Trettel, F, Di Bartolomeo, S, Renzi, M, Ragozzino, D, Eusebi, F

“…Experiments were conducted in both HEK cells and cerebellar neurons to investigate whether CXC chemokine receptor 2 (CXCR2) is functionally coupled to GluR1…”
Get full text

Kinetics and Mg2+ block of N-methyl-D-aspartate receptor channels during postnatal development of hippocampal CA3 pyramidal neurons by KHAZIPOV, R, RAGOZZINO, D, BREGESTOVSKI, P

“…Voltage-dependent magnesium block of N-methyl-D-aspartate-activated channels, and the N-methyl-D-aspartate component of excitatory synaptic currents were…”
Get full text

CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes by Piccinin, S., Di Angelantonio, S., Piccioni, A., Volpini, R., Cristalli, G., Fredholm, B.B., Limatola, C., Eusebi, F., Ragozzino, D.

Get full text

Functional Properties of Neuronal Nicotinic Acetylcholine Receptor Channels Expressed in Transfected Human Cells by Ragozzino, D., Fucile, S., Giovannelli, A., Grassi, F., Mileo, A. M., Ballivet, M., Alemà, S., Eusebi, F.

“…To study how subunit composition affects the functional properties of neuronal nicotinic acetylcholine receptors (nAChRs), we examined the behaviour of…”
Get full text

Fractalkine/CX3CL1 depresses central synaptic transmission in mouse hippocampal slices by BERTOLLINI, C, RAGOZZINO, D, GROSS, C, LIMATOLA, C, EUSEBI, F

Get full text

Acetylcholine-activated inward current induces cytosolic Ca2+ mobilization in mouse C2C12 myotubes by Giovannelli, A, Grassi, F, Limatola, C, Mattei, E, Ragozzino, D, Eusebi, F

“…We examined the spatiotemporal pattern of intracellular Ca2+ liberation in mouse myotubes by means of fluorescence imaging of cytosolic free Ca2+ together with…”
Get full text

Design and in vitro pharmacology of a selective gamma-aminobutyric acidC receptor antagonist by Ragozzino, D, Woodward, R M, Murata, Y, Eusebi, F, Overman, L E, Miledi, R

“…In mammals, receptors for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) are divided into three pharmacological classes, which are denoted…”
Get more information

Dual Ca2+ modulation of glycinergic synaptic currents in rodent hypoglossal motoneurones by Mukhtarov, Marat, Ragozzino, Davide, Bregestovski, Piotr

“…Glycinergic synapses are implicated in the coordination of reflex responses, sensory signal processing and pain sensation. Their activity is pre- and…”
Get full text

ATP release during cell swelling activates a Ca 2+ -dependent Cl - current by autocrine mechanism in mouse hippocampal microglia by Murana, E, Pagani, F, Basilico, B, Sundukova, M, Batti, L, Di Angelantonio, S, Cortese, B, Grimaldi, A, Francioso, A, Heppenstall, P, Bregestovski, P, Limatola, C, Ragozzino, D

“…Microglia cells, resident immune cells of the brain, survey brain parenchyma by dynamically extending and retracting their processes. Cl channels, activated in…”
Get full text

Stimulation of chemokine CXC receptor 4 induces synaptic depression of evoked parallel fibers inputs onto Purkinje neurons in mouse cerebellum by Ragozzino, Davide, Renzi, Massimiliano, Giovannelli, Aldo, Eusebi, Fabrizio

“…In the present work, we studied the effects of the stimulation of the chemokine CXC receptor 4 (CXCR4) by the stromal-derived cell growth factor-1α (SDF-1α) on…”
Get full text

CX 3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes by Piccinin, S., Di Angelantonio, S., Piccioni, A., Volpini, R., Cristalli, G., Fredholm, B.B., Limatola, C., Eusebi, F., Ragozzino, D.

“…We characterized the role of adenosine receptor (AR) subtypes in the modulation of glutamatergic neurotransmission by the chemokine fractalkine (CX 3CL1) in…”
Get full text